Type of Mesothelioma:
Kinetically Controlled Polyelectrolyte Complex Assembly of microRNA-Peptide Nanoparticles toward Treating Mesothelioma
Advanced Materials 2024 March 26 [Link] Caleb F Anderson, Anand Singh, Tyler Stephens, Chuong D Hoang, Joel P Schneider Abstract Broad size distributions and poor long-term colloidal stability of microRNA-carrying nanoparticles, especially those formed by polyelectrolyte complexation, represent major hurdles in realizing their clinical translation. Herein, peptide design is used alongside optimized flash nanocomplexation (FNC)…
Read MoreCharacterization of pleural mesothelioma by hierarchical clustering analyses using immune cells within tumor microenvironment
Pathobiology 2024 March 25 [Link] Shingo Inaguma, Chengbo Wang, Sunao Ito, Akane Ueki, Jerzy Lasota, Piotr Czapiewski, Renata Langfort, Janusz Rys, Joanna Szpor, Piotr Waloszczyk, Krzysztof Okoń, Wojciech Biernat, Shuji Takiguchi, David S Schrump, Markku Miettinen, Satoru Takahashi Abstract Introduction: Over the past decade, classifications using immune cell infiltration have been applied to many types…
Read MoreThe mental health and well-being implications of a mesothelioma diagnosis: A mixed methods study
European Journal of Oncology Nursing 2024 March 15 [Link] Virginia Sherborne, Emily Wood, Catriona R Mayland, Clare Gardiner, Caitlin Lusted, Anna Bibby, Angela Tod, Bethany Taylor, Stephanie Ejegi-Memeh Abstract Purpose: Mesothelioma is an incurable, asbestos-related cancer with a poor prognosis. There is scant evidence about the mental health and well-being impacts on patients and carers…
Read MoreCombination of EZH2 and ATM inhibition in BAP1-deficient mesothelioma
British Journal of Cancer 2024 March 22 [Link] Nick Landman, Danielle Hulsman, Jitendra Badhai, Jawahar Kopparam, Julian Puppe, Gaurav Kumar Pandey, Maarten van Lohuizen Abstract Background: More than half of mesothelioma tumours show alterations in the tumour suppressor gene BAP1. BAP1-deficient mesothelioma is shown to be sensitive to EZH2 inhibition in preclinical settings but only…
Read MoreThe IASLC Mesothelioma Staging Project: Proposals for Revisions of the ‘T’ Descriptors in the Forthcoming 9th Edition of the TNM Classification for Pleural Mesothelioma
Journal of Thoracic Oncology 2024 March 21 [Link] Ritu R Gill, Anna K Nowak, Dorothy J Giroux, Megan Eisele, Adam Rosenthal, Hedy Kindler, Andrea Wolf, Robert T Ripley, Andre Billé, David Rice, Isabelle Opitz, Andreas Rimner, Marc dePerrot, Harvey I Pass, Valerie W Rusch; IASLC Staging and Prognostic Factors Committee; Advisory Boards and Participating Institution…
Read MoreReliably making the primary diagnosis of mesothelioma utilizing serous fluid cytology specimens: an institutional experience
Journal of the American Society of Cytopathology 2024 March 2 [Link] Terri E Jones, Daniel L Geisler, Swikrity Upadhyay Baskota, N Paul Ohori, Jacqueline Cuda, Samer N Khader Abstract Introduction: The diagnosis of mesothelioma has historically been challenging, especially on serous fluid cytology (SFC). Distinguishing between reactive and neoplastic mesothelial cells can be difficult on…
Read MoreInvestigation of the appropriate viscosity of fibrinogen in repairing pleural defects using ventilation and anchoring in an ex vivo pig model
Journal of Cardiothoracic Surgery 2024 March 21 [Link] Akihiro Fukuda, Masaki Hashimoto, Yoshitaka Takegawa, Nobuyuki Kondo, Seiki Hasegawa Abstract Objective: Our previous study revealed that the viscosity of fibrinogen could influence the effectiveness of ventilation and anchoring (V/A) methods for controlling air leakages. Here, we examined the association between the viscosity of fibrinogen and effectiveness…
Read MoreCharacterization of KLHL14 anti-oncogenic action in malignant mesothelioma
Heliyon 2024 March 9 [Link] Angelo Canciello, Reyes Benot Domínguez, Barbara Barboni, Antonio Giordano, Andrea Morrione Abstract Malignant mesothelioma (MM) is a very aggressive neoplasia with a short life expectancy and limited therapeutic options. Thus, the identification of novel molecular targets is a matter of great urgency. Kelch-like (KLHL) proteins play an important role in…
Read MorePeritoneal Malignant Mesothelioma Metastasizing to Lymph Node in Young Male-a Case Report
Indian Journal of Surgical Oncology 2024 March [Link] Amanpreet Singh, Cherry Bansal, Disha Singla, Sarika More, Shivani Chabhra, Shazia Bashir Abstract Peritoneal malignant mesothelioma is an uncommon neoplasm with a poor prognosis. We hereby report a case of a 20-year-old male, first diagnosed on biopsy with axillary lymph node metastasis. He presented with abdominal pain…
Read MoreComplex Genomic Rearrangement Patterns in Malignant Pleural Mesothelioma due to Environmental Asbestos Exposure
Journal of Environmental Pathology, Toxicology, and Oncology 2024 [Link] Tunç Tuncel, Güntülü Ak, Hasan Veysi Güneş, Muzaffer Metintaş Abstract Malignant pleural mesothelioma (MPM) is a rare type of cancer, and its main risk factor is exposure to asbestos. Accordingly, our knowledge of the genomic structure of an MPM tumor is limited when compared to other…
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