Effect of the TAT-RasGAP(317-326) peptide on apoptosis of human malignant mesothelioma cells and fibroblasts exposed to meso-tetra-hydroxyphenyl-chlorin and light

Journal of Occupational & Environmental Medicine. 2007 Jul 27;88(1):29-35. Epub 2007 May 1. [Link] Olivier Pitteta, David Petermanna, David Michodb, Thorsten Kruegera, Cai Chenga, Hans-Beat Risa, and Christian Widmannb aDivision of Thoracic Surgery, University of Lausanne, Centre Hospitalier Universitaire Vaudois, 1011 Lausanne, Switzerland bDepartment of Physiology and Cellular Biology and Morphology, University of Lausanne, Switzerland…

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Treatment of malignant pleural mesothelioma

Gan To Kagaku Ryoho. 2007 Apr;34(4):520-6. [Link] Yusa T. Chiba Pleural Tumor Study Group. Abstract In Japan, it is predicted that mesothelioma will rapidly increase in the future. Malignant pleural mesothelioma that accounts for approximately 90% of mesothelioma as a whole has a median survival time of approximately nine months which is considered a poor…

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Preclinical Comparison of mTHPC and Verteporfin for Intracavitary Photodynamic Therapy of Malignant Pleural Mesothelioma

European Surgical Research. 2006;38(3):333-9. Epub 2006 Jun 19. [Link] Opitz I, Krueger T, Pan Y, Altermatt HJ, Wagnieres G, Ris HB. Thoracic Surgery Service, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland. Abstract Efficacy and tumour selectivity of photodynamic therapy with two clinically approved sensitizers (mTHPC, verteporfin) were assessed for focal intracavitary photodynamic therapy (PDT) in rodents…

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Management of malignant mesothelioma by decortication and adjunct phototherapy

Asian Cardiovascular and Thoracic Annals. 2006 Jun;14(3):206-9. [Link] Charles P Clarke, MBBS, Simon R Knight, MBBS, Freddy J Daniel, MBMS, Siven Seevanayagam, MBBS Austin Health, Heidelberg, Victoria, Australia For reprint information contact: CP Clarke, MBBS Tel: 61 3 9419 2477 Fax: 61 3 9417 1694 Email: clarkecp@bigpond.com.au

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Intraoperative photodynamic therapy of the chest cavity in malignant pleural mesothelioma bearing rats

Lasers in Surgery and Medicine. 2005 Oct 21;37(4):271-277 [Epub ahead of print] [Link] Krueger T, Pan Y, Tran N, Altermatt HJ, Opitz I, Ris HB. Thoracic Surgery Unit, University Hospital of Lausanne, CH-1011 Lausanne, Switzerland Abstract Background and Objective: Experimental assessment of anticancer effect, normal tissue damage, and toxicity of intrathoracic mTHPC-mediated photodynamic therapy (PDT)…

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Photodynamic therapy as an adjunct to surgery for malignant pleural mesothelioma

Lung Cancer. 2005 Jul;49 Suppl 1:S65-8. [Link] Ris HB. Division of Thoracic Surgery, Centre Hospitalier Universitaire Vaudoise (CHUV), CH 1011 Lausanne, Switzerland. Abstract Malignant pleural mesothelioma (MPM) is increasingly observed in industrial countries. Despite concerted efforts and combined treatments including surgery, chemotherapy and irradiation patients eventually succumb from relentless local progression of the disease. Recent…

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