Photodynamic Therapy (PDT)
Extended Pleurectomy-Decortication-Based Treatment for Advanced Stage Epithelial Mesothelioma Yielding a Median Survival of Nearly Three Years
The Annals of Thoracic Surgery 2016 November 5 [Epub ahead of print] Link] Friedberg JS, Simone CB 2nd, Culligan MJ, Barsky AR, Doucette A, McNulty S, Hahn SM, Alley E, Sterman DH, Glatstein E, Cengel KA Abstract BACKGROUND: The purpose of this study was to assess survival for patients with malignant pleural mesothelioma (MPM), epithelial…
Read MoreIllumination profile characterization of a light device for the dosimetry of intra-pleural photodynamic therapy for mesothelioma
Photodiagnosis and photodynamic therapy 2016 September 1 [Epub ahead of print] [Link] Munck C, Mordon S, Betrouni N Abstract BACKGROUND: Complete and homogeneous illumination of the pleural cavity is essential to the success of photodynamic therapy (PDT) for mesothelioma, but remains a challenge. Knowing the repartition and propagation of light around the light applicator could…
Read MoreAn IR Navigation System for Pleural PDT
Frontiers in Physics 2015 March [Link] Zhu TC, Liang X, Kim MM, Finlay JC, Dimofte A, Rodriguez C, Simone CB, Friedberg JS, Cengel KA. Abstract Pleural photodynamic therapy (PDT) has been used as an adjuvant treatment with lung-sparing surgical treatment for malignant pleural mesothelioma (MPM). In the current pleural PDT protocol, a moving fiber-based point…
Read MoreFluence plays a critical role on the subsequent distribution of chemotherapy and tumor growth delay in murine mesothelioma xenografts pre-treated by photodynamic therapy
Lasers in Surgery and Medicine 2015 January 12 [Epub ahead of print] [Link] Wang Y, Wang X, Le Bitoux MA, Wagnieres G, Vandenbergh H, Gonzalez M, Ris HB, Perentes JY, Krueger T. Abstract Background The pre-conditioning of tumor vessels by low-dose photodynamic therapy (L-PDT) was shown to enhance the distribution of chemotherapy in different tumor…
Read MoreA case of advanced malignant pleural mesothelioma treatment with chemotherapy and photodynamic therapy
Tuberculosis and Respiratory Diseases 2015 January [Link] Ryu JW, Kim YS. Abstract Malignant pleural mesothelioma (MPM) is an aggressive, treatment-resistant, and generally fatal disease. A 68-year-old male who was diagnosed with MPM at another hospital came to our hospital with dyspnea. We advised him to take combination chemotherapy but he refused to take the treatment.…
Read MorePhotodynamic therapy for lung cancer and malignant pleural mesothelioma
Seminars in Oncology 2014 December [Link] Simone CB 2nd, Cengel KA. Abstract Photodynamic therapy (PDT) is a form of non-ionizing radiation therapy that uses a drug, called a photosensitizer, combined with light to produce singlet oxygen ((1)O2) that can exert anti-cancer activity through apoptotic, necrotic, or autophagic tumor cell death. PDT is increasingly being used…
Read MoreCombination effect of photodynamic therapy using NPe6 with pemetrexed for human malignant pleural mesothelioma cells
International Journal of Oncology 2014 November 10 [Epub ahead of print] [Link] Maehara S, Usuda J, Ishizumi T, Ichinose S, Ohtani K, Inoue T, Imai K, Furumoto H, Kudo Y, Kajiwara N, Ohira T, Ikeda N. Abstract To identify a possible new treatment modality for malignant pleural mesothelioma (MPM), we examined whether combination treatment consisting…
Read MoreMultimodal therapy of malignant pleural mesothelioma: is the replacement of radical surgery imminent?
Interactive CardioVasic and Thoracic Surgery. 2012 Nov 21. [Epub ahead of print] [Link] Lindenmann J, Matzi V, Neuboeck N, Anegg U, Maier A, Smolle J, Smolle-Juettner FM. Division of Thoracic and Hyperbaric Surgery, Department of Surgery, Medical University of Graz, Austria. Abstract Aims: The accurate diagnosis of malignant pleural mesothelioma (MPM) is essential for therapeutic…
Read MoreMalignant mesothelioma 2008
Current Opinion in Pulmonary Medicine. 14(4):303-309, July 2008. [Link] Zervos MD, Bizekis C, Pass HI. Department of Cardiothoracic Surgery, Division of Thoracic Surgery, New York University School of Medicine, New York, USA. zervom01@med.nyu.edu Abstract Purpose of review: Mesothelioma is an aggressive malignancy of the pleura with poor survival. There will be approximately 3000 cases of…
Read MorePolyhematoporphyrin-mediated photodynamic therapy and decortication in palliation of malignant pleural mesothelioma: a clinical pilot study
Interactive Cardiovascular and Thoracic Surgery. 3:52-56(2004) [Link] Matzi V, Maier A, Woltsche M, Smolle-Jüttner FM. Department of Surgery, Division of Thoracic and Hyperbaric Surgery, University Medical School, Auenbruggerplatz 29, A-8036 Graz, Austria. Abstract The aim of this study was to evaluate the additional effect of intraoperative photodynamic therapy (PDT) under hyperbaric oxygenation (HBO) when compared…
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