Surgical phenotype of patients with peritoneal mesothelioma and a germline mutation

Cancer 2023 April 12 [Link] Yaniv Berger, Meghana Gadiraju, Ankit Dhiman, Katie Gilliam, Buerkley Opalecky, Heather Chen, Maria Helgeson, Oliver S Eng, Aliya N Husain, Michael W Drazer, Hedy L Kindler, Jane E Churpek, Kiran K Turaga Abstract Background: This study aimed to investigate if peritoneal mesothelioma (PM) patients with germline mutations (GM) have distinct…

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Surgical case report: The rare case of incidental retroperitoneal mesothelioma

International Journal of Surgery Case Reports 2023 April [Link] Yat Cheung Chung, Travis Ackermann, Yeu Sheng Ang Abstract Introduction and importance: This is a first reported case of isolated retroperitoneal mesothelioma. Most patients present with symptoms of abdominal pain, distension and weight loss. However, a minority of cases are asymptomatic and are found incidentally on…

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The robotic future of minimally invasive cytoreduction and hyperthermic intraperitoneal chemotherapy for peritoneal surface malignancies

Chinese Clinical Oncology 2023 March 13 [Link] Joanna Ortega, Theofano Orfanelli, Edward Levine, Ioannis T Konstantinidis Abstract Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (CRS/HIPEC) has been increasingly utilized for peritoneal surface malignancies. This has been commonly utilized for a variety of neoplasms, but, especially mucinous neoplasms of the appendix, ovarian cancer, gastric cancer, colorectal cancer…

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Benign multicystic peritoneal mesothelioma mimicking mucinous ovarian neoplasm with pseudomyxoma peritonei

BMJ Case Reports 2023 March 7 [Link] Ceylan Altintas Taslicay, Maila Asadullayeva, Aziz Hakki Civriz, Gokhan Posteki Abstract Cystic mesothelioma, also known as benign multicystic peritoneal mesothelioma (BMPM), is a rare neoplasm and one of the five main histological types of peritoneal mesothelioma. Although it is usually considered benign histologically, it is increasingly accepted as…

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Mesothelioma In Situ Mimicking Well-differentiated Papillary Mesothelial Tumor

The American Journal of Surgical Pathology 2023 March 6 [Link] Francoise Galateau-Salle, Trevor Hamilton, Andrea MacNeill, Véronique Hofman, Ruth Sequeiros, Christine Sagan, Nolwenn Le Stang, Andrew Churg Abstract We have previously hypothesized that well-differentiated papillary mesothelial tumor (WDPMT) consists of 2 morphologically identical lesions, one of which is true WDPMT, while the other is a…

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Long-Term Survival in Patients Treated with Cytoreduction and Heated Intraperitoneal Chemotherapy for Peritoneal Mesothelioma at a Single High-Volume Center

Annals of Surgical Oncology 2023 February 8 [Link] Cristian D Valenzuela, Ian B Solsky, Richard A Erali, Steven D Forsythe, Christopher W Mangieri, Bigyan B Mainali, Gregory Russell, Kathleen C Perry, Konstantinos I Votanopoulos, Perry Shen, Edward A Levine Abstract Background: Malignant peritoneal mesothelioma (MPM) is a rare diagnosis with a dismal prognosis if untreated.…

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NR4A3 fusions characterize a distinctive peritoneal mesothelial neoplasm of uncertain biological potential with pure adenomatoid/microcystic morphology

Genes, Chromosomes, and Cancer 2022 December 16 [Link] Abbas Agaimy, Luka Brcic, Laurence M Briski, Yin P Hung, Michael Michal, Michal Michal, G Petur Nielsen, Robert Stoehr, Andrew E Rosenberg Abstract A focal adenomatoid-microcystic pattern is not uncommon in peritoneal mesothelioma, but tumors composed almost exclusively of this pattern are distinctly rare and have not…

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Extensive Peritonectomy is an Independent Risk Factor for Cisplatin HIPEC-Induced Acute Kidney Injury

Annals of Surgical Oncology 2022 December 10 [Link] Lukas F Liesenfeld, Eva Quiring, Mohammed Al-Saeedi, Christian Nusshag, Markus W Büchler, Martin Schneider Abstract Background: Cisplatin (CDDP)-containing hyperthermic intraperitoneal chemotherapy (HIPEC) is frequently applied in selected patients with peritoneal malignancies derived from ovarian cancer, gastric cancer, and primary peritoneal mesothelioma. HIPEC with CDDP increases perioperative morbidity,…

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Conditional Survival Following Cytoreductive Surgery with Hyperthermic Intraperitoneal Chemotherapy for Peritoneal Surface Malignancies: An Analysis from the US HIPEC Collaborative

Annals of Surgical Oncology 2022 October 30 [Link] Eliza W Beal, Shruthi Srinivas, Chengli Shen, Alex Kim, Fabian M Johnston, Jonathan Greer, Daniel E Abbott, Courtney Pokrzywa, Mustafa Raoof, Travis E Grotz, Jennifer L Leiting, Keith Fournier, Sean Dineen, Benjamin Powers, Jula Veerapong, Anai Kothari, Ugwuji Maduekew, Shishir Maithel, Gregory C Wilson, Sameer H Patel,…

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Desmoid-type fibromatosis in the setting of malignant peritoneal mesothelioma: a case report of two rare diseases

World Journal of Surgical Oncology 2022 September 28 [Link] Stephanie N Gregory, Audra A Satterwhite, H Richard Alexander, Andrew M Blakely Abstract Background: Desmoid-type fibromatosis (DTF) is a rare benign lesion that usually arises from the abdominal wall or extremities and rarely from the mesentery or intrabdominal organs. Malignant peritoneal mesothelioma is also a rare,…

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