Angiogenesis
Epidemiology, molecular biology, diagnostic and therapeutic strategy of malignant pleural mesothelioma in 2007 – an update
Revue des Maladies Respiratoires. 2007 Oct;24(8 Pt 2):6S157-64. [Link] Porret E, Madelaine J, Galateau-Sallé F, Bergot E, Zalcman G. Service de Pneumologie, Pôle Coeur-Poumons-Vaisseaux, Université Basse-Normandie, CHU de Caen, France. Abstract Malignant pleural mesothelioma (MPM) is a rare tumour due to occupational asbestos exposure. The incidence of MPM will continue to increase until 2020-2030. The…
Read MoreNicotinic acetylcholine receptors in cancer: multiple roles in proliferation and inhibition of apoptosis
Trends in Pharmacological Sciences. 2008 Mar;29(3):151-8. Epub 2008 Feb 11. [Link] Egleton RD, Brown KC, Dasgupta P. Department of Pharmacology, Physiology and Toxicology, Joan C. Edwards School of Medicine, 1 John Marshall Drive, Huntington, WV 25755, USA. Abstract Nicotinic acetylcholine receptors (nAChRs) constitute a heterogeneous family of ion channels that mediate fast synaptic transmission in…
Read MoreEGFR And PDGFR Differentially Promote Growth In Malignant Epitheloid Mesothelioma Of Short- And Long-term Survivors
Thorax. 2007 Dec 17 [Epub ahead of print] [Link] Kothmaier H, Quehenberger F, Halbwedl I, Morbini P, Demirag F, Zeren H, Comin CE, Murer B, Cagle PT, Attanoos R, Gibbs AR, Gallateau-Salle F, Popper HH. Institute of Pathology, Medical University of Graz, Austria. Abstract Malignant pleural mesothelioma (MPM) is an asbestos-related tumour difficult to detect…
Read MoreImmunohistochemical expression and distribution of VEGFR-3 in malignant mesothelioma
Diagnostic Cytopathology. 2007 Dec;35(12):786-91. [Link] Filho AL, Baltazar F, Bedrossian C, Michael C, Schmitt FC. Life and Health Sciences Research Institute, Health Sciences School, University of Minho, Braga, Portugal. Abstract Homogeneity of mesothelial and lymphatic endothelial cells, express some markers that are presumed to be exclusive of the endothelium was recently reported. This similarity is…
Read MoreMorphologic and functional imaging of malignant pleural mesothelioma
European Journal of Radiology. 2007 Dec;64(3):356-66. Epub 2007 Oct 22. [Link] Yamamuro M, Gerbaudo VH, Gill RR, Jacobson FL, Sugarbaker DJ, Hatabu H. Department of Radiology and Surgery, Brigham and Women’s Hospital and Harvard Medical School, 75 Francis Street, Boston, MA 02115, United States. Abstract Malignant pleural mesothelioma (MPM) is an aggressive tumor that arises…
Read MoreExpression of Activated and Latent Signal Transducer and Activator of Transcription 3 in 303 Non–Small Cell Lung Carcinomas and 44 Malignant Mesotheliomas: Possible Role for Chemotherapeutic Intervention
Archives of Pathology and Laboratory Medicine: Vol. 131, No. 9, pp. 1350–1360. [Link] Achcar Rde O, Cagle PT, Jagirdar J. Department of Pathology, University of Texas Health Sciences Center, San Antonio, USA. Abstract Context: Signal transducer and activator of transcription 3 (STAT3) is constitutively activated in diverse human cancers and plays a critical role in…
Read MorePhase II testing of sunitinib: the National Cancer Institute of Canada Clinical Trials Group IND Program Trials IND.182-185
Current Oncology. 2007 Aug;14(4):154-61. [Link] Buckstein R, Meyer RM, Seymour L, Biagi J, Mackay H, Laurie S, Eisenhauer E. Division of Hematology, Odette Cancer Center, Toronto, Ontario. Abstract Sunitinib (SU11248) is an orally bioavailable inhibitor that affects the receptor tyrosine kinases involved in tumour proliferation and angiogenesis, including vascular endothelial growth factor (vegf) receptors 1,…
Read MoreInhibition of c-Src expression and activation in malignant pleural mesothelioma tissues leads to apoptosis, cell cycle arrest, and decreased migration and invasion
Molecular Cancer Therapeutics. 2007 Jul;6(7):1962-72. [Link] Tsao AS, He D, Saigal B, Liu S, Lee JJ, Bakkannagari S, Ordonez NG, Hong WK, Wistuba I, Johnson FM. Department of Thoracic/Head and Neck Medical Oncology, M. D. Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 432, Houston, TX 77030, USA. astsao@mdanderson.org Abstract Malignant pleural mesothelioma (MPM) is a…
Read MoreTreatment of malignant pleural mesothelioma
Gan To Kagaku Ryoho. 2007 Apr;34(4):520-6. [Link] Yusa T. Chiba Pleural Tumor Study Group. Abstract In Japan, it is predicted that mesothelioma will rapidly increase in the future. Malignant pleural mesothelioma that accounts for approximately 90% of mesothelioma as a whole has a median survival time of approximately nine months which is considered a poor…
Read MoreIdentification and characterization of putative tumor suppressor NGB, a GTP-binding protein that interacts with the neurofibromatosis 2 protein
Molecular and Cellular Biology. 2007 Mar;27(6):2103-19. Epub 2007 Jan 8. [Link] Lee H, Kim D, Dan HC, Wu EL, Gritsko TM, Cao C, Nicosia SV, Golemis EA, Liu W, Coppola D, Brem SS, Testa JR, Cheng JQ. Department of Pathology, H. Lee Moffitt Cancer Center, University of South Florida, Tampa, FL 33612, USA. Abstract Mutations…
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