The Cell-Adhesion and Signaling Molecule PECAM-1 is a Molecular Mediator of Resistance to Genotoxic Chemotherapy

Cancer Biology & Therapy. 2006 Dec;5(12):1699-707. Epub 2006 Dec 30. [Link] Bergom C, Goel R, Paddock C, Gao C, Newman DK, Matsuyama S, Newman PJ. Blood Research Institute, Blood Center of Wisconsin, Milwaukee, Wisconsin, USA; Department of Cell Biology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA. Abstract Defects in the regulation of apoptotic pathways have…

Read More

The biological differences between ovarian serous carcinoma and diffuse peritoneal malignant mesothelioma

Seminars in Diagnostic Pathology. 2006 Feb;23(1):35-43. [Link] Davidson B, Risberg B, Berner A, Bedrossian CW, Reich R. Department of Pathology, Norwegian Radium Hospital-National Hospital, University of Oslo, Oslo, Norway. ben.davidson@radiumhospitalet.no Abstract Recent improvements in immunohistochemistry panels used for differentiating ovarian serous carcinoma/primary peritoneal carcinoma (OC/PPC) from diffuse malignant peritoneal mesothelioma (DMPM) have resulted in improved…

Read More

Drug targets to pro-angiogenetic factors with special reference to primary peritoneal mesothelioma

Endocrine, Metabolic & Immune Disorders Drug Targets. 2006 Sep;6(3):271-7. [Link] Ranieri G, Ruggieri E, Falco G, Zizzo N, Mattioli E, Zito AF, Patruno R, Gasparini G. Department of Experimental Oncology, National Cancer Institute of Bari, Bari, Italy. giroran@tiscalinet.it Abstract Angiogenesis is necessary for growth and the spread of human tumors. Animal studies also suggest that…

Read More

Biology and management of malignant pleural mesothelioma

European Journal of Cancer. 2006 Sep 19; [Epub ahead of print] [Link] Paolo A. Zucali1, a and Giuseppe Giacconea aDepartment of Medical Oncology, VU University Medical Center, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands Received 18 July 2006;  accepted 19 July 2006.  Available online 20 September 2006. Abstract Malignant mesothelioma is an aggressive tumour,…

Read More

Novel orthotopic implantation model of human malignant pleural mesothelioma (EHMES-10 cells) highly expressing vascular endothelial growth factor and its receptor

Cancer Science. 2006 Mar;97(3):183-91. [Link] Nakataki E, Yano S, Matsumori Y, Goto H, Kakiuchi S, Muguruma H, Bando Y, Uehara H, Hamada H, Kito K, Yokoyama A, Sone S. Department of Internal Medicine and Molecular Therapeutics, University of Tokushima Graduate School, 3-18-15 Kuramoto-cho, Tokushima 770-8503, Japan. Abstract Malignant pleural mesothelioma (MPM) is closely related to…

Read More

Antiangiogenic therapies for mesothelioma

Hematology/Oncology Clinics of North America. 2005 Dec;19(6):1137-45. [Link] Dowell JE, Kindler HL. University of Texas-Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-8852, USA; Division of Hematology & Oncology, Dallas Veterans Affairs Medical Center, Dallas, TX, USA. Abstract A large body of preclinical evidence suggests that angiogenesis plays a key role in the pathogenesis…

Read More