Pleural Mesothelioma Diagnosis for the Pulmonologist: Steps Along the Way

Cancers 2025 December 1 [Link] Alberto Fantin, Nadia Castaldo, Ernesto Crisafulli, Giulia Sartori, Filippo Patrucco, Horiana B Grosu, Paolo Vailati, Giuseppe Morana, Vincenzo Patruno, Stefano Kette, Avinash Aujayeb, Aleš Rozman Abstract Background/Objectives: Malignant pleural mesothelioma (MPM) is a rare, aggressive tumor with a poor prognosis and complex diagnostic pathways. Pulmonologists often play a central role…

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Mesothelioma Contrast Pharmacokinetics: A Feasibility Trial of the Use of Pharmacokinetic Analysis in Small-Volume Pleural Malignancy

Radiology. Cardiothoracic Imaging 2026 February [Link] Gordon W Cowell, Selina Tsim, David B Stobo, Colin Noble, Catherine A Humphreys, Rosie Woodward, John E Foster, Craig Dick, Kevin G Blyth Abstract Purpose To assess the feasibility of dynamic contrast-enhanced (DCE) MRI-derived pharmacokinetic factor acquisition and performance in patients with suspected small-volume pleural malignancy. Materials and Methods…

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Manganese-doped nanotheranostic system for MRI-guided photothermal therapy of malignant pleural mesothelioma: in vivo study

Frontiers in Chemistry 2025 September 11 [Link] Lichang Lei, Hongjiao Zi, ShaoLei Kang, Hui Duan, Zhenghua Zhang, Chao Gao, Ruoyun Xu, Dan Han Abstract Introduction: Magnetic Resonance Imaging (MRI)-guided photothermal therapy (PTT) holds significant promise for the treatment of solid tumors, however, its diagnostic and therapeutic efficacy in malignant pleural mesothelioma (MPM) remains underexplored. To…

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Potential advantage of magnetic resonance imaging in detecting thoracic wall infiltration in pleural mesothelioma: A retrospective single-center analysis

JTCVS Open 2024 October 22 [Link] Isabel Barreto, Sabine Franckenberg, Thomas Frauenfelder, Isabelle Opitz, Olivia Lauk Abstract Objectives: Thoracic wall infiltration in pleural mesothelioma determines the extent of resection and can be an important prognostic factor. Currently, standardized imaging for restaging after neoadjuvant systemic therapy comprises contrast-enhanced computed tomography or positron emission tomography. Additional thoracic…

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Case report: Radiological features of a case of desmoplastic malignant mesothelioma of peritoneum

Frontiers in Oncology 2024 December 11 [Link] Jingchao Wang, Heping Deng Abstract Desmoplastic malignant peritoneal mesothelioma (DMPM) is an extremely rare and aggressive subtype of sarcomatoid malignant mesothelioma, originating from the mesothelial lining of body cavities. It is characterized by significant local invasiveness and poor prognosis. The nonspecific symptoms of DMPM often result in delayed…

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Predictive potential of MRI in differentiating the predominant component in biphasic pleural mesothelioma

European Journal of Radiology 2024 May 26 [Link] Ritu R Gill, William G Richards, Hillary Heiling, Emanuele Mazzola, Yin P Hung, Ravi T Seethamraju, Lucian R Chirieac, Raphael Bueno Abstract Purpose: To assess the potential of apparent diffusion coefficient (ADC) values derived from diffusion weighted (DW) MRI preoperatively to predict the predominant histologic component among…

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Implementation of a high-resolution, high-contrast magnetic resonance imaging protocol with extended delayed phases for peritoneal mesothelioma

Quantitative Imaging in Medicine and Surgery 2024 March 15 [Link] Milica Medved, Hunter D D Witmer, Ankit Dhiman, Yaniv Berger, Scott K Sherman, Enal S Hindi, Samuel G Armato 3rd, Ingrid S Reiser, Aytekin Oto, Roger M Engelmann, Hedy L Kindler, Nisa C Oren, Carla B Harmath, Kiran K Turaga Abstract Background: Imaging of peritoneal…

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Diagnostic value of computed tomography and magnetic resonance imaging in ovarian malignant mesothelioma

BMC Medial Imaging 2023 December 14 [Link] Hai-Tao Wang, Ai-Jing Li, Ji-Yong Gao, Liang-Jiong Wang, Yu-Tao Wang, Wen-Ying Yu, Jian Zhang Abstract Objective: To investigate the diagnostic value of computed tomography (CT) and magnetic resonance imaging (MRI) in ovarian malignant mesothelioma (OMM). Methods: The clinical and imaging data of 10 pathologically-confirmed OMM patients were analyzed…

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Surgical case report: The rare case of incidental retroperitoneal mesothelioma

International Journal of Surgery Case Reports 2023 April [Link] Yat Cheung Chung, Travis Ackermann, Yeu Sheng Ang Abstract Introduction and importance: This is a first reported case of isolated retroperitoneal mesothelioma. Most patients present with symptoms of abdominal pain, distension and weight loss. However, a minority of cases are asymptomatic and are found incidentally on…

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Cytoreductive Surgical Treatment of Pleural Mesothelioma in a Porcine Model Using Magnetic-Resonance-Guided Focused Ultrasound Surgery (MRgFUS) and Radiofrequency Ablation (RFA)

Tomography 2022 September 3 [Link] Marcia Costa, Carolina Fernandes, Matt Eames, Arik Hananel , John P Mugler 3rd, Jhosep Huaromo, Jack B Yang, Jaime Mata Abstract A combination of surgery and chemotherapy is the most effective treatment available for Malignant Pleural Mesothelioma (MPM). However, both cause significant collateral damage and cannot eliminate residual microscopic disease.…

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