Survival in patients with malignant pleural effusions who developed pleural infection: a retrospective case review from 6 UK Centers

Chest 2014 November 27 [Epub ahead of print] [Link] Bibby AC, Clive AO, Slade GC, Morely AJ, Fallon J, Psallidas I, Pepperell JC, Slade MG, Stanton AE, Rahman NM, Maskell NA. Abstract Objectives Malignant pleural effusion (MPE) incidence is increasing and prognosis remains poor. In-dwelling pleural catheters (IPCs) relieve symptoms, but increase the risk of…

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Extrapleural pneumonectomy plus rib resection for malignant pleural mesothelioma: a case report

Journal of Cardiothoracic Surgery 2014 November 18 [Epub ahead of print] [Link] Yamashita Y, Harada H,Mukaida H, Kaneko M. Abstract We report a case of a 58-year-old Japanese man with epithelioid-type MPM, with a left chest wall protruding tumor, who underwent extrapleural pneumonectomy and chest wall resection. Postsurgical pathology showed that surgical margins were free…

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Scrotal Peritoneal Mesothelioma on PET/CT

Clinical Nuclear Medicine 2014 December [Link] Ozguven S, Aras M, Dede F, Ones T, Turoglu HT. Abstract Although malignant mesothelioma originating from the tunica vaginalis has been reported in the literature, direct invasion of malignant peritoneal mesothelioma to the scrotal cavity has not been described yet. Herein, we presented a diffuse malignant peritoneal mesothelioma extending…

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Acute lower limb ischemia complicating pemetrexed and carboplatin combination chemotherapy for malignant pleural mesothelioma

Annali Italiani di Chirurgia 2014 November [Link] Valerio S, Bracale UM, Giribono AM, Viviani E, Caioni F, Del Guercio L. Abstract Pemetrexed and Carboplatin are two well-known chemioterapic agents used for the treatment of many tumors, especially for lung cancer and mesothelioma. Peripheral ischemic events related to Pemetrexed and Carboplatin are rarely reported. We herein…

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Malignant mesothelioma presenting as dysphagia diagnosed by endoscopic ultrasound

Annals of Gastroenterology 2014 [Link] Al-Bawardy B, Gorospe EC, Leggett C. Abstract Malignant mesothelioma is a tumor involving the pleura or peritoneum. It characteristically presents with dyspnea, pleural effusions and pleuritic chest pain. Its diagnosis is established by pleural fluid cytology or pleural biopsy [1]. Based on our literature review, there are less than 10…

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Clinical aspects of asbestos-related diseases-what are the unresolved topics?

Journal of Occupational Environmental Medicine. 2014 October. Link Banks DE. Abstract Objective Despite awareness of the health risks associated with asbestos fiber inhalation and the decline in U.S. utilization (about 0.1% of the yearly peak amount), illnesses associated with exposure persist. Those with disease typically describe excessive exposures in the remote past, yet excessive exposures…

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Electron Microscopy Remains the Gold Standard for the Diagnosis of Epithelial Malignant Mesothelioma: A Case Study

Ultrastructural Pathology. 2014 September 30. [Epub ahead of time] Link Oczypok EA, Oury TD. Abstract This is a case of idiopathic epithelial malignant mesothelioma in a 47-year-old mechanic. The advent of a large battery of immunochemical markers has provided new tools for the diagnosis of mesothelioma in recent years; however, immunostaining can often be misleading…

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Systematic review of response rates of sarcomatoid malignant pleural mesotheliomas in clinical trials

Lung Cancer. 2014 September 1 [Epub ahead of print] [Link] Mansfield AS, Symanowski JT, Peikert T. Abstract Rationale Malignant pleural mesothelioma is an almost universally fatal malignancy primarily related to asbestos exposure. Based on the differences in immunologic markers and gene expression between histologic subtypes of mesothelioma, and our clinical impression that response rates vary…

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