Pleural
Artificial Intelligence in Pleural Diseases: Current Applications and Next Steps
Thoracic Research and Practice 2026 January 30 [Link] Ferhan Karataş, Öner Dikensoy Abstract Pleural diseases pose a significant burden on healthcare systems due to diagnostic challenges and high costs. Artificial intelligence (AI) has the potential to provide faster, more accurate, and more reliable results in the diagnosis of these diseases. This review evaluates the current…
Read MoreReal-world outcomes of first-line immunotherapy and subsequent systemic therapies in pleural mesothelioma: a multicenter study in China
Translational Lung Cancer Research 2025 December 31 [Link] Binhe Tian, Boyu Sun, Zixiang Zhou, Shuman Kuang, Jiongyuan Li, Weixuan Pan, Zhe Zhu, Xiaoyan Si, Li Zhang, Jun Liu, Juhong Shi, Fang Wu, Haitao Zhao, Hanping Wang Abstract Background: Pleural mesothelioma (PM) has a poor prognosis, and immune checkpoint inhibitors (ICIs) have reshaped first-line therapy. However,…
Read MoreMulti-omic screening for pleural mesothelioma in Asbestos-Exposed Populations: A literature review and Recommendations
Lung Cancer 2026 February [Link] Kathleen Zwijsen, Ellen Heirwegh, Eline Schillebeeckx, Elly Marcq, Adrian Covaci, Ken Op de Beeck, Jan P van Meerbeeck, Jo Raskin, Annelies Janssens, Annemiek Snoeckx, Kevin Lamote Abstract Objectives: Pleural mesothelioma (PM) is an aggressive thoracic cancer related to historical exposure to asbestos fibres. Symptoms often appear at an advanced stage,…
Read MoreThe Accuracy of Video-Assisted Thoracic Surgery Pleural Biopsy in Patients with Suspected Diffuse Pleural Mesothelioma: A Real-Life Study
Journal of Clinical Medicine 2025 December 20 [Link] Ludovica Balsamo, Enrica Migliore, Eleonora Della Beffa, Luisa Delsedime, Paolo Olivo Lausi, Daniela Di Cuonzo, Filippo Lococo, Paraskevas Lyberis, Dario Mirabelli, Mauro Giulio Papotti, Enrico Ruffini, Francesco Guerrera Abstract Background: The heritage of occupational and environmental asbestos exposure in Piedmont, Italy, has resulted in an enduring diffuse…
Read MorePrognostic Value of Fibroblast Activation Protein-Directed PET Imaging in Pleural Mesothelioma
Journal of Nuclear Medicine 2026 January 22 [Link] Lukas Kessler, Felix Schwaning, Martin Metzenmacher, Kim M Pabst, Marcel Opitz, Marcel Wiesweg, Clemens Aigner, Till Ploenes, Servet Bölükbas, Fabian Doerr, Martin Stuschke, Lale Umutlu, Michael Nader, Dirk Theegarten, Wilfried E Eberhardt, Martin Schuler, Ken Herrmann, Wolfgang P Fendler, David Kersting, Hubertus Hautzel Abstract High expression of…
Read MoreReal-world outcomes of first-line immunotherapy and subsequent systemic therapies in pleural mesothelioma: a multicenter study in China
Translational Lung Cancer Research 2025 December 31 [Link] Binhe Tian, Boyu Sun, Zixiang Zhou, Shuman Kuang, Jiongyuan Li, Weixuan Pan, Zhe Zhu, Xiaoyan Si, Li Zhang, Jun Liu, Juhong Shi, Fang Wu, Haitao Zhao, Hanping Wang Abstract Background: Pleural mesothelioma (PM) has a poor prognosis, and immune checkpoint inhibitors (ICIs) have reshaped first-line therapy. However,…
Read MoreBAP1-loss in mesothelioma: molecular mechanisms and clinical opportunities
Oncogene 2026 February [Link] Jasper H L T van Genugten, Dean A Fennell, Paul Baas Abstract Mesothelioma is an aggressive cancer that is often characterized by loss of the BRCA1-associated protein 1 (BAP1) tumor suppressor gene. This alteration typically occurs as an early clonal event in mesothelioma development, making it a promising candidate for both…
Read MoreBAP1-loss in mesothelioma: molecular mechanisms and clinical opportunities
Oncogene 2026 February [Link] Jasper H L T van Genugten, Dean A Fennell, Paul Baas Abstract Mesothelioma is an aggressive cancer that is often characterized by loss of the BRCA1-associated protein 1 (BAP1) tumor suppressor gene. This alteration typically occurs as an early clonal event in mesothelioma development, making it a promising candidate for both…
Read MoreTargeting key proteins of pleural mesothelioma using plumbagin-indole-3-propionic acid ester: Insights from network pharmacology, molecular dynamics simulation and machine learning-based analysis
Computational Biology and Chemistry 2026 April [Link] Binjawhar Dalal Nasser, Chitra Loganathan, Revathi Ramalingam, Ancy Iruthayaraj Abstract This study explores the network pharmacology (NP) and molecular dynamics (MD) simulation analysis of pleural mesothelioma (PM) related enzymes. Through the investigation of 1253 associated genes, culminating in a protein-protein interaction (PPI) network constructed using the STRING database.…
Read MoreIntegrating polygenic and methylation risk scores for pleural mesothelioma risk stratification
International Journal of Cancer 2025 December 30 [Link] Khadija Sana Hafeez, Carla Debernardi, Alessandra Allione, Elton Jalis Herman, Simonetta Guarrera, Daniela Ferrante, Anna Aspesi, Marika Sculco, Marta La Vecchia, Carlotta Sacerdote, Federica Grosso, Christina M Lill, Giovanna Masala, Marcela Guevara, Matthias B Schulze, Salvatore Panico, Yaszan Asgari, Seehyun Park, Giovanna Tagliabue, Anne Tjønneland, Antonio Agudo,…
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