Cytopathology 2021 May 28 [Link] Patrizia Straccia, Daniele Magnini, Rocco Trisolini, Filippo Lococo, Marco Chiappetta, Alessandra Cancellieri Abstract Objective: Malignant mesothelioma (MM) is usually diagnosed by histological examination of tissue samples; however, effusion cytology offers an opportunity to identify a strong possibility for mesothelioma diagnosis at an early stage. We conducted a retrospective analysis of…

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American Journal of Clinical Pathology 2021 May 12 [Link] Jefree J Schulte, David B Chapel, Richard Attanoos, Luka Brcic, Juliet Burn, Kelly J Butnor, Nina Chang, Heather Chen, Sanja Dacic, Marc De Perrot, Junya Fukuoka, Francoise Galateau-Salle, Theresa Godschachner, Kenzo Hiroshima, Sonja Klebe, Thomas Krausz, Leslie Litzky, Alberto M Marchevsky, Jeffrey Mueller, Kazuki Nabeshima, Andrew…

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Thoracic Cancer 2021 May 5 [Link] Bertrand Chollet, Julien Guinde, Sophie Laroumagne, HervĂ© Dutau, Philippe Astoul Abstract Background: Malignant pleural mesothelioma (MPM) is a rare, highly aggressive and deadly disease with a poor patient life expectancy. A few years ago, the main challenge was the histological diagnosis of this disease; at present, the search for…

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Journal of Biochemistry 2021 April 1 [Link] Haruhiko Fujihira, Daisuke Takakura, Atsushi Matsuda, Masaaki Abe, Michiyo Miyazaki, Tomomi Nakagawa, Kazunori Kajino, Kaori Denda-Nagai, Miki Noji, Okio Hino, Tatsuro Irimura Abstract Mesothelioma is a highly aggressive tumor associated with asbestos exposure and is histologically classified into three types: epithelioid-type, sarcomatoid-type, and biphasic-type. The prognosis of mesothelioma…

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The American Journal of Surgical Pathology 2021 March 29 [Link] Julia R Naso, Simon Cheung, Diana N Ionescu, Andrew Churg Abstract The separation of malignant mesothelioma from non-small cell lung carcinomas can be a difficult problem. Sex-determining region Y box 6 (SOX6) and disabled homolog 2 (DAB2) have recently been proposed as sensitive/specific markers of…

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International Journal of Surgical Pathology 2021 March 17 [Link] Kai-Bo Chen, Ya-Jing Huang, Yi Huang, Zhi-Wei Wu, Xiao-Li Jin, Hang Zhang, Xue-Ping Xiang, Lin Chen, Li Chen Abstract Sarcomatoid malignant mesothelioma (MM) is a rare and aggressive disease, and its diagnosis is challenging. A 60-year-old man presented with a recurrent subcutaneous mass in his right…

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Tumori 2021 March 15 [Link] Pietro Gino Barbieri, Dario Consonni, Manuela Schneider Abstract Background: Definition of histologic subtype of malignant pleural mesothelioma (MPM) is important for management of patients, because surgical treatment improves prognosis for patients with epithelioid but not biphasic or sarcomatoid MPM. In a series of necropsies performed in a hospital specialized for…

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Virchows Archiv 2021 February 11 [Link] Zheng Hua Piao, Xin Cheng Zhou, Jia Yi Chen Abstract Sarcomatoid malignant mesothelioma (SMM) tends to occur in the pleura and is morphologically similar to lung sarcomatoid carcinoma (LSC) and organizing pleuritis (OP). Because SMM often does not express mesothelial markers, it is very difficult to distinguish from LSC…

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Cancers 2020 December 20 [Link] Roberta Affatato, Paolo Mendogni, Alessandro Del Gobbo, Stefano Ferrero, Francesca Ricci, Massimo Broggini, Lorenzo Rosso Abstract Background: Malignant pleural mesothelioma (MPM) is a very aggressive tumor originating from mesothelial cells. Although several etiological factors were reported to contribute to MPM onset, environmental exposure to asbestos is certainly a major risk…

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