Peritoneal (Abdominal Mesothelioma)
Drug sensitivity tumor cell clusters in malignant peritoneal mesothelioma
Journal of Surgical Oncology 2024 August 25 [Link] Yan-Dong Su, Ru Ma, Yu-Bin Fu, He-Liang Wu, Xin-Li Liang, Yi-Tong Liu, Yang Yu, Zhi-Ran Yang, Yan Li Abstract Background: To explore the most effective adjuvant chemotherapy regimen for malignant peritoneal mesothelioma (MPM) through patient derived tumor-like cell clusters (PTC) drug sensitivity test. Methods: PTC were cultured…
Read MoreThe Effect of Cuproptosis-Related Proteins on Macrophage Polarization in Mesothelioma is Revealed by scRNA-seq
Biological Trace Element Research 2024 August 23 [Link] Jia-Xin Xu, Li-Jing Ma, Li-Ying Tu, Qi-Sheng Tang, Bian Wu 3 4, Li-Hong Jiang Abstract High invasiveness mesothelioma is a malignant tumor of the peritoneum or pleura. The effect of cuproptosis on mesothelioma (MESO) is still unknown, though. The Cancer Genome Atlas (TCGA) and the Gene Expression…
Read MoreThe Effect of Cuproptosis-Related Proteins on Macrophage Polarization in Mesothelioma is Revealed by scRNA-seq
Biological Trace Element Research 2024 August 23 [Link] Jia-Xin Xu, Li-Jing Ma, Li-Ying Tu, Qi-Sheng Tang, Bian Wu, Li-Hong Jiang Abstract High invasiveness mesothelioma is a malignant tumor of the peritoneum or pleura. The effect of cuproptosis on mesothelioma (MESO) is still unknown, though. The Cancer Genome Atlas (TCGA) and the Gene Expression Omnibus (GEO)…
Read MoreClinical Characteristics and Outcomes of Patients with Well-Differentiated Papillary Peritoneal Mesothelial Tumors
Annals of Surgical Oncology 2024 November [Link] Michael Offin, Nicole Aguirre, Soo Ryum Yang, Jennifer L Sauter, Georgios Karagkounis, Mostafa Mohamed, Andrea Cercek, Ritika Kundra, Yanming Zhang, Hui Mei Wang, Marty P Morris, Marc Ladanyi, Garrett M Nash, Marjorie G Zauderer Abstract Purpose: Well-differentiated papillary peritoneal mesothelial tumors (WDPMTs) are understudied and discrete from peritoneal…
Read MoreA gut microbiota rheostat forecasts responsiveness to PD-L1 and VEGF blockade in mesothelioma
Nature Communications 2024 August 21 [Link] Min Zhang, Aleksandra Bzura, Essa Y Baitei, Zisen Zhou, Jake B Spicer, Charlotte Poile, Jan Rogel, Amy Branson, Amy King, Shaun Barber, Tamihiro Kamata, Joanna Dzialo, James Harber, Alastair Greystoke, Nada Nusrat, Daniel Faulkner, Qianqian Sun, Luke Nolan, Jens C Hahne, Molly Scotland, Harriet Walter, Liz Darlison, Bruno Morgan,…
Read MoreSTK11 (LKB1) immunohistochemistry is a sensitive and specific marker for STK11 adnexal tumours
Histopathology 2024 November [Link] Amir Dehghani, Aarti E Sharma, Stephanie E Siegmund, Chrystalle K Carreon, Colin J R Stewart, Fabiola Medeiros, Jelena Mirkovic, Marisa R Nucci, Christopher P Crum, Jason L Hornick, Brooke E Howitt, W Glenn McCluggage, David L Kolin Abstract Aims: STK11 adnexal tumour is a rare, recently described malignant neoplasm that is…
Read MoreA gut microbiota rheostat forecasts responsiveness to PD-L1 and VEGF blockade in mesothelioma
Nature Communications 2024 August 21 [Link] Min Zhang, Aleksandra Bzura, Essa Y Baitei, Zisen Zhou, Jake B Spicer, Charlotte Poile, Jan Rogel, Amy Branson, Amy King, Shaun Barber, Tamihiro Kamata, Joanna Dzialo, James Harber, Alastair Greystoke, Nada Nusrat, Daniel Faulkner, Qianqian Sun, Luke Nolan, Jens C Hahne, Molly Scotland, Harriet Walter, Liz Darlison, Bruno Morgan,…
Read MoreCase report: ATM A1159T mutation in malignant peritoneal mesothelioma may be associated with tumor recurrence
SAGE Open Medical Case Reports 2024 August 16 [Link] Ying Li, Jintao Yang, Bei Zheng, Na Yan, Wenjuan Yang, Xinling Xie, Guoshu Xu, Meiling Zhang Abstract Malignant peritoneal mesothelioma is an exceedingly rare malignant tumor. Herein, we present a case of malignant peritoneal mesothelioma in a 59-year-old Chinese female patient who was stable after treatment…
Read MoreStemness and hybrid epithelial-mesenchymal profiles guide peritoneal dissemination of malignant mesothelioma and pseudomyxoma peritonei
International Journal of Cancer 2024 August 15 [Link] Nayana Lazzari, Giulia Rigotto, Barbara Montini, Paola Del Bianco, Elena Moretto, Federica Palladino, Rocco Cappellesso, Marco Tonello, Carola Cenzi, Antonio Scapinello Maria Assunta Piano, Carlo Riccardo Rossi, Piero Dalerba, Pierluigi Pilati, Antonio Sommariva, Maria Luisa Calabrò Abstract Intrabdominal dissemination of malignant mesothelioma (MM) and pseudomyxoma peritonei (PMP)…
Read MoreMajor response of a peritoneal mesothelioma to nivolumab and ipilimumab: a case report, molecular analysis and review of literature
Frontiers in Oncology 2024 July 18 [Link] Marie-Florence Reveneau, Julien Masliah-Planchon, Manuel Fernandez, Abdenour Ouikene, Bernard Dron, Innocenti Dadamessi, Charles Dayen, Lisa Golmard, Bruno Chauffert Abstract Malignant peritoneal mesothelioma (MPM) is a rare tumor associated with a poor prognosis and a lack of consensus regarding treatment strategies. While the Checkmate 743 trial demonstrated the superiority…
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