Malignant mesothelioma

Orphanet Journal of Rare Diseases. 2008 Dec 19;3:34. [Link] Moore AJ, Parker RJ, Wiggins J. Department of Respiratory Medicine, Wexham Park Hospital, Wexham, Slough, Berkshire, UK. a.moore@ic.ac.uk Abstract Malignant mesothelioma is a fatal asbestos-associated malignancy originating from the lining cells (mesothelium) of the pleural and peritoneal cavities, as well as the pericardium and the tunica…

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Peritoneal Mesothelioma

Current Treatment Options in Oncology. 2008 Jun;9(2-3):180-90. Epub 2008 Oct 8. [Link] Hesdorffer ME, Chabot J, DeRosa C, Taub R. Mesothelioma Applied Research Foundation, Santa Barbara, CA, USA. mhesdorer@curemeso.org Abstract Opinion statement: Malignant peritoneal mesothelioma (MPM) is an aggressive neoplasm that rapidly spreads within the confines of the abdominal cavity to involve most accessible peritoneal…

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Diagnosis, Staging, and Surgical Treatment of Malignant Pleural Mesothelioma

Current Treatment Options in Oncology. 2008 Jun;9(2-3):158-70. Epub 2008 Aug 29. [Link] Kent M, Rice D, Flores R. Thoracic Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA. Abstract Opinion statement: The clinical presentation of malignant pleural mesothelioma (MPM) is nonspecific. The process to obtain the correct diagnosis can be challenging…

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Open lung-sparing surgery for malignant pleural mesothelioma: the benefits of a radical approach within multimodality therapy

European Journal of Cardio-Thoracic Surgery. 2008 Jul 23. [Epub ahead of print] [Link] Nakas A, Trousse DS, Martin-Ucar AE, Waller DA. Department of Thoracic Surgery, Glenfield Hospital, Groby Road, Leicester LE3 9QA, United Kingdom. Abstract Objective: To identify the optimal debulking procedure in patients with malignant pleural mesothelioma who are not suitable for extrapleural pneumonectomy…

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Malignant mesothelioma: current status and perspective in Japan and the world

General Thoracic and Cardiovascular Surgery. 2008 Jul;56(7):317-23. Epub 2008 Jul 8. [Link] Hasegawa S, Tanaka F. Department of Thoracic Surgery, Hyogo College of Medicine, 1-1 Mukogawa-cho, Nishinomiya, 663-8501, Japan, hasegawa@hyo-med.ac.jp. Abstract Malignant pleural mesothelioma (MPM) is associated with a poor prognosis; and to make things worse, its incidence is increasing throughout the world. Surgical management…

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Multimodal Therapy for Malignant Pleural Mesothelioma Including Extrapleural Pneumonectomy

Zentralblatt fur Chirurgie. 2008 Jun;133(3):231-237. [Link] Sienel W, Kirschbaum A, Passlick B. Abteilung Thoraxchirurgie, Chirurgische Universitätsklinik, Universitätsklinikum Freiburg. Abstract Multimodal therapy including neoadjuvant chemotherapy with subsequent extrapleural pneumonectomy and postoperative radiotherapy has been shown to improve the survival of patients with malignant pleural mesothelioma (MPM) if they are selected carefully. Careful patient selection is required…

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Trimodality Treatment of Malignant Pleural Mesothelioma

Journal of Thoracic Oncology. 3(5):499-504, May 2008. [Link] Batirel HF, Metintas M, Caglar HB, Yildizeli B, Lacin T, Bostanci K, Akgul AG, Evman S, Yuksel M. Marmara University Hospital, Department of Thoracic Surgery, Istanbul, Turkey. hbatirel@marmara.edu.tr Abstract Introduction: Multimodality treatment has achieved significant success in local control and treatment of early-stage malignant pleural mesothelioma patients.…

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Individual versus standard quality of life assessment in a phase II clinical trial in mesothelioma patients: Feasibility and responsiveness to clinical changes

Lung Cancer. 2008 Apr 21 [Epub ahead of print] [Link] Ribi K, Bernhard J, Schuller JC, Weder W, Bodis S, Jörger M, Betticher D, Schmid RA, Stupp R, Ris HB, Stahel RA; for the Swiss Group for Clinical Cancer Research (SAKK). Swiss Group for Clinical Cancer Research (SAKK) Coordinating Center, Effingerstr. 40, CH-3008 Bern, Switzerland.…

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Outcome after extrapleural pneumonectomy for malignant pleural mesothelioma

European Journal of Cardio-Thoracic Surgery. 2008 Apr 11 [Epub ahead of print] [Link] Aigner C, Hoda MA, Lang G, Taghavi S, Marta G, Klepetko W. Department of Cardio-Thoracic Surgery, Medical University of Vienna, Waehringer Guertel 18–20, 1090 Vienna, Austria. Abstract Background: Malignant pleural mesothelioma is a mainly asbestos-related neoplasm that occurs with increasing frequency and…

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Combined resection, intraperitoneal chemotherapy, and whole abdominal radiation for the treatment of malignant peritoneal mesothelioma

American Journal of Clinical Oncology. 2008 Feb;31(1):49-54 [Link] Hesdorffer ME, Chabot JA, Keohan ML, Fountain K, Talbot S, Gabay M, Valentin C, Lee SM, Taub RN. Division of Oncology, Columbia University New York, New York, USA. mhesdorffer@curemeso.org Abstract Objective: We report a single-institution Phase I or II trial of surgical debulking, intraperitoneal chemotherapy, and immunotherapy…

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