Relapse pattern and second-line treatment following multimodality treatment for malignant pleural mesothelioma

European Journal of Cardiothoracic Surgery 2015 November 20 [Epub ahead of print] [Link] Kostron A, Friess M, Crameri O, Inci I, Schneiter D, Hillinger S, Stahel R, Weder W, Opitz I. Abstract Objectives To analyse the relapse pattern and influence of second-line treatment after recurrence of malignant pleural mesothelioma (MPM) in patients who had previously…

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Biologic therapy and gene therapy in the multimodality treatment of malignant pleural mesothelioma

Annals of Translational Medicine 2015 October [Link] Viti A, Bertolaccini L, Terzi A. Abstract The last years have witnessed an abrupt paradigm shift in cancer treatment owing to the discoveries concerning the relationships between the immune system and neoplastic cells. In the field of malignant mesothelioma, which, despite painstaking efforts, remains an incurable form of…

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Trimodality strategy for treating malignant pleural mesothelioma: results of a feasibility study of induction pemetrexed plus cisplatin followed by extrapleural pneumonectomy and postoperative hemithoracic radiation (Japan Mesothelioma Interest Group 0601 Trial)

International Journal of Clinical Oncology 2015 November 17 [Epub ahead of print] [Link] Hasegawa S, Okada M, Tanaka F, Yamanaka T, Soejima T, Kamikonya N, Tsujimura T, Fukuoka K, Yokoi K, Nakano T. Abstract Purpose We conducted a prospective multi-institutional study to determine the feasibility of trimodality therapy (TMT) comprising induction chemotherapy followed by extrapleural…

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Trimodality Treatment of Malignant Pleural Mesothelioma: An Institutional Review

American Journal of Clinical Oncology 2015 August 27 [Epub ahead of print] [Link] Kapeles M, Gensheimer MF, Mart DA, Sottero TL, Kusano AS, Truong A, Farjah F, Laramore GE, Stelzer KJ, Patel SA. Abstract Objective Malignant pleural mesothelioma (MPM) is a deadly disease with varying treatment options. This study retrospectively describes treatment practices at the…

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A new prognostic score supporting treatment allocation for multimodality therapy for malignant pleural mesothelioma- A review of 12 years’ experience

Journal of Thoracic Oncology 2015 August 27 [Epub ahead of print] [Link] Opitz I, Friess M, Kestenholz P, Schneiter D, Frauenfelder T, Nguyen-Kim DL, Seifert B, Hoda MA, Klepetko W, Stahel RA, Weder W. Abstract Introduction Treatment of malignant pleural mesothelioma (MPM) remains a clinical challenge. The aim of this study was to identify selection…

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Prognostic Coronary Surgery in a Case of Malignant Mesothelioma previously managed with Trimodality Treatment

Heart, Lung & Circulation Journal. 2014 April 18. [Epub ahead of print] [Link] Bannon PG, Bulliard C, Dhurandhar V, McCaughan BC, Robinson BM. Abstract We report a case of malignant pleural mesothelioma treated with trimodality treatment. At three years after the extrapleural pneumonectomy, coronary artery revascularisation surgery for NSTEMI was performed in view of favourable…

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Factors predicting poor survival after lung-sparing radical pleurectomy of IMIG stage III malignant pleural mesothelioma

European Journal of Cardiothoracic Surgery. 2012 Dec 13. [Epub ahead of print] [Link] Bölükbas S, Eberlein M, Kudelin N, Demes M, Stallmann S, Fisseler-Eckhoff A, Schirren J. Department of Thoracic Surgery, Dr.-Horst-Schmidt-Klinik (Teaching Hospital of Johannes Gutenberg University, Mainz), Wiesbaden, Germany. Abstract Objectives: The role of radical pleurectomy (RP) in the management of IMIG stage…

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Surgical management of malignant pleural mesothelioma

p>Thoracic Surgery Clinics.. 2013 Feb;23(1):73-87. doi: 10.1016/j.thorsurg.2012.10.002. [Link] Yanagawa J, Rusch V. Thoracic Surgery Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA. Abstract The uniquely diffuse nature of malignant pleural mesothelioma (MPM) makes it difficult to diagnose, stage, and treat. In addition, it is a relatively uncommon…

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Multimodal therapy of malignant pleural mesothelioma: is the replacement of radical surgery imminent?

Interactive CardioVasic and Thoracic Surgery. 2012 Nov 21. [Epub ahead of print] [Link] Lindenmann J, Matzi V, Neuboeck N, Anegg U, Maier A, Smolle J, Smolle-Juettner FM. Division of Thoracic and Hyperbaric Surgery, Department of Surgery, Medical University of Graz, Austria. Abstract Aims: The accurate diagnosis of malignant pleural mesothelioma (MPM) is essential for therapeutic…

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