Gemcitabine (Gemzar)
Multicenter trial of neo-adjuvant chemotherapy followed by extrapleural pneumonectomy in malignant pleural mesothelioma
Annals of Oncology. 2007 18(7):1196-1202. [Link] Weder W, Stahel R, Bernhard J, Bodis S, Vogt P, Ballabeni P, Lardinois D, Betticher D, Schmid R, Stupp R, Ris H, Jermann M, Mingrone W, Roth A, Spiliopoulos A; On behalf of the Swiss Group for Clinical Cancer Research. Department of Thoracic Surgery. Abstract Background: The aim of…
Read MoreInduction chemotherapy, extrapleural pneumonectomy, and postoperative high-dose radiotherapy for locally advanced malignant pleural mesothelioma: a phase II trial
Journal of Thoracic Oncology. 2006 May;1(4):289-95. [Link] Flores RM, Krug LM, Rosenzweig KE, Venkatraman E, Vincent A, Heelan R, Akhurst T, Rusch VW. Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA. floresr@mskcc.org Abstract Introduction: Extrapleural pneumonectomy (EPP) and adjuvant high-dose radiation therapy (RT) are associated with a median survival of…
Read MoreFour-Modality Therapy in Malignant Pleural Mesothelioma: A Phase II Study
Journal of Thoracic Oncology. 2(3):237-242, March 2007 [Link] Lucchi M, Chella A, Melfi F, Dini P, Tibaldi C, Fontanini G, Mussi A. Division of Thoracic Surgery, Cardiac and Thoracic Department, University of Pisa, Italy. m.lucchi@med.unipi.it Abstract Background: Treatment approaches in malignant pleural mesothelioma (MPM) patients range from mere palliation to aggressive anticancer therapy, and there…
Read MoreInduction chemotherapy, extrapleural pneumonectomy (EPP) and adjuvant hemi-thoracic radiation in malignant pleural mesothelioma (MPM): Feasibility and results
Lung Cancer. 2007 Jul;57(1):89-95. Epub 2007 Apr 2. [Link] Rea F, Marulli G, Bortolotti L, Breda C, Favaretto AG, Loreggian L, Sartori F. Division of Thoracic Surgery, University of Padua, Policlinico di Padova, Italy. federico.rea@unipd.it Abstract Background: Trimodality therapy seems to be the best treatment for malignant pleural mesothelioma (MPM). A large experience served to…
Read MorePreliminary Data Suggestive Of A Novel Translational Approach To Mesothelioma Therapy: Imatinib Mesylate With Gemcitabine Or Pemetrexed
Thorax. Published Online First: 20 February 2007. doi:10.1136/thx.2006.069872 [Link] Pietro Bertino 1, Camillo Porta 2, Dario Barbone 1, Serena Germano 1, Sara Busacca 1, Sabrina Pinato 1, Giancarlo Tassi 3, Roberto Favoni 4, Giovanni Gaudino 1* and Luciano Mutti 5 1 DISCAFF Department and DFB Center, University of Piemonte Orientale "A. Avogadro", Novar, Italy 2…
Read MoreA phase II study of intrapleural immuno-chemotherapy, pleurectomy/decortication, radiotherapy, systemic chemotherapy and long-term sub-cutaneous IL-2 in stage II-III malignant pleural mesothelioma
European Journal of Cardiothoracic Surgery. 2007 Mar;31(3):529-34. Epub 2006 Dec 26. [Link] Lucchi M, Chella A, Melfi F, Dini P, Ambrogi M, Fino L, Fontanini G, Mussi A. Division of Thoracic Surgery, Cardiac and Thoracic Department, University of Pisa, Pisa, Italy. Abstract Objective: From therapeutic nihilism to extremely aggressive management, there is a wide range…
Read MoreA retrospective analysis of malignant pleural mesothelioma patients treated either with chemotherapy or best supportive care between 1990 and 2005; A single institution experience
Lung Cancer. 2006 Dec 14; [Epub ahead of print] [Link] Muzaffer Metintasa, Guntulu Aka, Sinan Erginela, Fusun Alatasa, Huseyin Yildirima, Emel Kurta and Selma Metintasb aDepartment of Chest Diseases, Osmangazi University Medical Faculty, Turkey bDepartment of Public Health, Osmangazi University Medical Faculty, Eskişehir, Turkey Abstract The aim of this study was to investigate the efficacy…
Read MoreA case of malignant mesothelioma presenting with recurrent pneumothorax
Nihon Kokyuki Gakkai Zasshi. 2006 Nov;44(11):807-11. [Link] Katayam N, Tokuda A, Nakatsumi Y, Oribe Y, Fujimura M. Department of Respiratory Medicine, Kanazawa Municipal Hospital. Abstract A 71-year-old man was found to have right hydropneumothorax by chest X-ray film on a regular checkup. Thoracic drainage and bullectomy by thoracoscopy did not improve the pneumothorax, so pleurodesis…
Read MoreMalignant pleural mesothelioma in a 14-year-old boy with right aortic arch
The Japanese Journal of Thoracic Cardiovascular Surgery. 2006 Oct;54(10):458-61. [Link] Hosaka M, Ohde Y, Nakagawa K, Okumura T, Kameya T, Kondo H. Division of Thoracic Surgery, Shizuoka Cancer Center, 1007 Shimonagakubo, Nagaizumi-cho, Sunto-gun, Shizuoka 411-8777, Japan. Abstact We report successful surgery for malignant pleural mesothelioma (MPM) in a 14-year-old boy with right aortic arch. Pleural…
Read MoreChemotherapy in malignant pleural mesothelioma
Revista Portuguesa de Pneumologia. 2005 Nov;11(6 Suppl 1):14-5. [Link] Barata F, Cortesao N, Marques A, Figueiredo A. Servico Pneumologia Centro Hospitalar de Coimbra. Abstract Rational and objective: During the last few years a variety of new chemotherapy agents have been used (mostly in combination) in the treatment of malignant pleural mesothelioma (MPM). Combination therapy with…
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