SV40 oncoproteins enhance asbestos-induced DNA double-strand breaks and abrogate senescence in murine mesothelial cells

Cancer Research. 67, 3637-3645, April 15, 2007. [Link] Jodie R. Pietruska and Agnes B. Kane Brown University, Department of Pathology and Laboratory Medicine, Providence, Rhode Island Requests for reprints: Agnes B. Kane, Department of Pathology and Laboratory Medicine, Brown University, Box G-E534, Providence, RI 02912. Phone: 401-863-1110; Fax: 401-863-9008; E-mail: Agnes_Kane@brown.edu. Abstract SV40 virus has…

Read More

Erionite and asbestos differently cause transformation of human mesothelial cells

International Journal of Cancer. 2007 Jul 1;121(1):12-20. [Link] Bertino P, Marconi A, Palumbo L, Bruni BM, Barbone D, Germano S, Dogan AU, Tassi GF, Porta C, Mutti L, Gaudino G. Department of DISCAFF and DFB Center, University of Piemonte Orientale A. Avogadro, Novara, Italy. Abstract Malignant mesothelioma (MM) is an aggressive tumor associated with environmental…

Read More

Relationship between the malignant mesothelioma and simian virus 40 in China: a study of 17 cases

Zhonghua Bing Li Xue Za Zhi. 2006 Oct;35(10):602-5. [Link] Jin ML, Li X, Luo J, Zhao HY, Liu Y. Department of Pathology, Beijing Chao Yang Hospital of Capital Medical University, Beijing 100020, China. kinmokuran@163.com Abstract Objective: To investigate whether simian virus 40 (SV40) was related to patients of malignant mesothelioma in China. Methods: Paraffin-embeded samples…

Read More

SV40 and human cancer: A review of recent data

International Journal of Cancer. 2007 Jan 15;120(2):215-23. [Link] Shah KV. Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD. Abstract An unknown proportion of formalin-inactivated poliovirus vaccine lots administered to millions of US residents between 1955 and 1963 was contaminated with small amounts of infectious simian virus 40 (SV40),…

Read More

A novel SV40 TAg transgenic model of asbestos-induced mesothelioma: malignant transformation is dose dependent

Cancer Research. 2006 Nov 15;66(22):10786-94.Click here to read [Link] Cleo Robinson1, Ivonne van Bruggen1, Amanda Segal2, Melissa Dunham1, Amanda Sherwood1, Frank Koentgen3, Bruce W.S. Robinson1 and Richard A. Lake1 1 School of Medicine and Pharmacology and Western Australian Institute for Medical Research, University of Western Australia; 2 Path Centre, Sir Charles Gairdner Hospital; and 3…

Read More

Mesothelioma mortality in Europe: impact of asbestos consumption and simian virus 40

Orphanet Journal of Rare Diseases.. 2006 Nov 7;1:44 [Link] Katharina Leithner1, Andreas Leithner2, Heimo Clar2 , Andreas Weinhaeusel3 , Roman Radl2 , Peter Krippl4 , Peter Rehak5 , Reinhard Windhager2 , Oskar A Haas6 and Horst Olschewski1 1Department of Pulmonology, University Clinic of Internal Medicine, Medical University Graz, Graz, Austria 2Department of Orthopedic Surgery, Medical…

Read More

The pathogenesis of mesothelioma

Seminars in Diagnostic Pathology. 2006 Feb;23(1):56-60. [Link] Carbone M, Bedrossian CW. Thoracic Oncology Program, Cancer Research Center of Hawaii, University of Hawaii, Honolulu, Hawaii 96813, USA. mcarbone@crch.hawaii.edu Abstract Widespread asbestos exposure during the past century has been linked to the dramatic increased incidence of malignant mesothelioma (MM), a malignancy that was so rare until 1950-1960…

Read More

Epidemiology of peritoneal mesothelioma: a review

Annals of Oncology. 2006 Oct 9; [Epub ahead of print] [Link] P. Boffetta 1 * 1 International Agency for Research on Cancer, Lyon, France * To whom correspondence should be addressed: P. Boffetta, E-mail: boffetta@iarc.fr Abstract The epidemiology of peritoneal mesothelioma is complicated by possible geographic and temporal variations in diagnostic practices. The incidence rates…

Read More

Crocidolite asbestos and SV40 are cocarcinogens in human mesothelial cells and in causing mesothelioma in hamsters

Proceedings of the National Academy of Sciences of the United States of America. 2006 Sep 11; [Epub ahead of print] [Link] Kroczynska B, Cutrone R, Bocchetta M, Yang H, Elmishad AG, Vacek P, Ramos-Nino M, Mossman BT, Pass HI, Carbone M. Thoracic Oncology Program, Cardinal Bernardin Cancer Center, Loyola University Chicago, Maywood, IL 60153; Abstract…

Read More