A secretomics analysis reveals major differences in the macrophage responses towards different types of carbon nanotubes

Nanotoxicology 2014 October 17 [Epub ahead of print] [Link] Palomaki J, Sund J, Vippola M, Kinaret P, Greco D, Savolainen K, Puustinen A, Alenius H. Abstract Certain types of carbon nanotubes (CNT) can evoke inflammation, fibrosis and mesothelioma in vivo, raising concerns about their potential health effects. It has been recently postulated that NLRP3 inflammasome…

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Size- and shape-dependent pleural translocation, deposition, fibrogenesis and mesothelial proliferation by multi-walled carbon nanotubes

Cancer Science. 2014 May 11. [Epub ahead of print] [Link] Alexander DB, Fukamachi K, Futakuchi M, Hirose A, Kanno J, Numano T, Omori T, Suzui M, Tsuda H, Xu J. Abstract Multi-walled carbon nanotubes (MWCNT) have a fibrous structure similar to asbestos, raising concern that MWCNT exposure may lead to asbestos-like diseases. Previously we showed…

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Occupational Nanosafety Considerations for Carbon Nanotubes and Carbon Nanofibers

Acc Chem Res. Dec 5. [Epub ahead of print] [Link] Castranova V, Schulte PA, Zumwalde RD. National Institute for Occupational Safety and Health , Morgantown, West Virginia, United States Abstract Carbon nanotubes (CNTs) are carbon atoms arranged in a crystalline graphene lattice with a tubular morphology. CNTs exhibit high tensile strength, possess unique electrical properties,…

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