Asbestos exposure and histological subtype of malignant mesothelioma

Occupational and Environmental Medicine 2016 August 19 [Epub ahead of print] [Link] Franklin P, Alfonso H, Reid A, Olsen N, Shilkin KB, Brims F, de Klerk N, Musk AW Abstract BACKGROUND: Malignant mesothelioma (MM) has distinct histological subtypes (epithelioid, sarcomatoid and biphasic) with variable behaviour and prognoses. It is well recognised that survival time varies…

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Software for Apportionment of Asbestos-Related Mesotheliomas

Canadian Respiratory Journal 2016 [Epub 2016 May 18] [Link] Ross RM Abstract Patients with an asbestos-related mesothelioma may be legally entitled to financial compensation. In this context, a physician may be called upon to apportion the contribution of an asbestos containing product or facility where there was asbestos exposure in the development of that individual’s…

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Incidence of malignant mesothelioma in Aboriginal people in Western Australia

Australian and New Zealand Journal of Public Health 2016 Jul 3 [Epub ahead of print] [Link] Franklin P, Reid A, Olsen N, Peters S, de Klerk N, Brims F, Threlfall T, Murray R, Musk AB. Abstract OBJECTIVES: To describe the incidence of malignant mesothelioma (MM) in Aboriginal people in Western Australia (WA) and determine the…

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Fluoro-edenite and carbon nanotubes: The health impact of ‘asbestos-like’ fibers

Experimental and Therapeutic Medicine 2016 January [Link] Miozzi E, Rapisarda V, Marconi A, Costa C, Polito I, Spandidos DA, Libra M, Fenga C. Abstract Several decades have passed since Wagner et al demonstrated a causal link between asbestos fibre inhalation and the development of pleural mesothelioma in 1960. It was later suggested that pleural plaques…

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Carbon Nanotube and Asbestos Exposures Induce Overlapping but Distinct Profiles of Lung Pathology in Non-Swiss Albino CF-1 Mice

Toxicology Pathology 2016 February 2 [Epub ahead of print] [Link] Frank EA, Carreira VS, Birch ME, Yadav JS. Abstract Carbon nanotubes (CNTs) are emerging as important occupational and environmental toxicants owing to their increasing prevalence and potential to be inhaled as airborne particles. CNTs are a concern because of their similarities to asbestos, which include…

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Asbestos and multi-walled carbon nanotubes generate distinct oxidative responses in inflammatory cells

Journal of Clinical Biochemistry and Nutrition 2015 March [Link] Funahashi S, Okazaki Y, Ito D, Asakawa A, Nagai H, Tajima M, Toyokuni S. Abstract Asbestos exposure is considered a social burden by causing mesothelioma. Despite the use of synthetic materials, multi-walled carbon nanotubes (MWCNTs) are similar in dimension to asbestos and produce mesothelioma in animals.…

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Potential Occupational Risks Associated with Pulmonary Toxicity of Carbon Nanotubes

Occupational Medicine & Health Affairs 2014 [Link] Manke A, Luanpitpong S, Rojanasakul Y. Abstract Given their remarkable properties, carbon nanotubes (CNTs) have made their way through various industrial and medicinal applications and the overall production of CNTs is expected to grow rapidly in the next few years, thus requiring an additional recruitment of workers. However,…

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The carcinogenic effect of various multi-walled carbon nanotubes (MWCNTs) after intraperitoneal injection in rats

Particle and Fibre Toxicology 2014 November 20 [Epub ahead of print] [Link] Rittinghausen S, Hackbarth A, Creutzenberg O, Ernst H, Heinrich U, Leonhardt A, Shaudien D. Abstract Background Biological effects of tailor-made multi-walled carbon nanotubes (MWCNTs) without functionalization were investigated in vivo in a two-year carcinogenicity study. In the past, intraperitoneal carcinogenicity studies in rats…

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