Flex-rigid pleuroscopic biopsy with the SB knife Jr is a novel technique for diagnosis of malignant or benign fibrothorax

Journal of Thoracic Disease 2016 November [Link] Wang XB, Yin Y, Miao Y, Eberhardt R, Hou G, Herth FJ, Kang J Abstract Diagnosing pleural effusion is challenging, especially in patients with malignant or benign fibrothorax, which is difficult to sample using standard flexible forceps (SFF) via flex-rigid pleuroscopy. An adequate sample is crucial for the…

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Turning back the Wheel: Inducing Mesenchymal to Epithelial Transition via Wilms Tumor 1 Knockdown in Human Mesothelioma Cell Lines to Influence Proliferation, Invasiveness, and Chemotaxis

Pathology Oncology Research 2017 January 4 [Epub ahead of print] [Link] Plönes T, Fischer M, Höhne K, Sato H, Müller-Quernheim J, Zissel G Abstract Malignant pleural mesothelioma (MPM) is a highly aggressive tumor that arises from the surface of the pleura and is associated with a history of asbestos exposure. The tumor is characterized by…

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Metachronous Uterine Endometrioid Adenocarcinoma and Peritoneal Mesothelioma in Lynch Syndrome: A Case Report

International Journal of Surgical Pathology 2016 November [Epub ahead of print] [Link] Lu Y, Milchgrub S, Khatri G, Gopal P Abstract Lynch syndrome is a hereditary disease with germline mutation in a DNA mismatch repair gene, most often presenting with colorectal and/or endometrial carcinomas; however, the spectrum of Lynch syndrome-associated tumors is expanding. In this…

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The role of surgical intervention in lung cancer with carcinomatous pleuritis

Journal of Thoracic Disease 2016 November [Link] Fukui T, Yokoi K Abstract Patients with non-small cell lung cancer (NSCLC) associated with carcinomatous pleuritis are currently classified as having stage IV disease per the 7th edition of the tumor-node-metastasis (TNM) system, which means that the disease is deemed incurable. In fact, the 5-year survival rate of…

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Malignant pleural mesothelioma with lacrimal gland metastasis

Acta Ophthalmologica 2016 December 9 [Epub 2016 July 16] [Link] Hanafi H, Verdijk RM, Paridaens D Abstract PURPOSE: To describe a rare clinical case of biopsy-proven metastatic mesothelioma of the lacrimal gland which responded well to chemo and radiation therapy. METHODS: Interventional case report. RESULTS: A 55-year-old woman with an untreated malignant biopsy-proven pleural mesothelioma…

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Chest wall resection for mesothelioma recurrence after surgery

Asian Cardiovascular & Thoracic Annals 2016 November [Epub 2016 October 9] [Link] Bertoglio P, Fanucchi O, Ricciardi S, Chella A, Lucchi M, Mussi A Abstract Malignant pleural mesothelioma is an aggressive and usually fatal disease, and its optimal management is still under debate. Surgery for recurrent malignant mesothelioma has been reported rarely in highly selected…

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