Case Study
A pilot study of volumetric-modulated arc therapy for malignant pleural mesothelioma
Journal of Applied Clinical Medical Physics 2016 March [Link] Runxiao L1, Yankun C1, Lan W Abstract Malignant pleural mesothelioma (MPM) is an extremely difficult disease to treat. This pilot study investigates the feasibility of using volumetric-modulated arc therapy (VMAT) for malignant pleural mesothelioma (MPM), and compares VMAT to static field intensity-modulated radiotherapy (IMRT) for five…
Read MoreNon-Hodgkin Lymphoma and Pleural Mesothelioma in a Person Exposed to Asbestos
Turk Patologi 2017 February [Epub ahead of print] [Link] Bianchi C, Bianchi T Abstract Non-Hodgkin lymphoma and pleural mesothelioma may co-exist in the same patient. A large cell non-Hodgkin lymphoma of the inguinal lymph nodes was diagnosed in a 73-year-old woman. The patient was treated by chemotherapy. She did not receive radiotherapy. The patient had…
Read MoreAsbestos fibres detected by scanning electron microscopy in the gallbladder of patients with malignant pleural mesothelioma (MPM)
Journal of Microscopy 2017 April [Epub January 9] [Link] Grosso F, Croce A, Trincheri NF, Mariani N, Libener R, Degiovanni D, Rinaudo C Abstract Gallbladders from patients affected by both malignant pleural mesothelioma (MPM) and important gallbladder disorders were analyzed to verify the presence of asbestos fibres. Histological thin sections were analyzed by optical microscope…
Read MoreThe Immune Microenvironment, Genome -Wide Copy Number Aberrations and Survival in Mesothelioma
Journal of Thoracic Oncology 2017 February [Epub ahead of print] [Link] Thapa B, Salcedo A, Lin X, Walkiewicz M, Murone C, Ameratunga M, Asadi K, Deb S, Barnett SA, Knight S, Mitchell P, Watkins DN, Boutros PC, John T Abstract INTRODUCTION: Results of recent clinical studies of immune checkpoint inhibitors in malignant pleural mesothelioma (MPM)…
Read MoreAnti-CTLA-4 therapy for malignant mesothelioma
Immunotherapy 2017 March [a href=”https://www.ncbi.nlm.nih.gov/pubmed/28231719″>Link] Guazzelli A, Bakker E, Krstic-Demonacos M, Lisanti MP, Sotgia F, Mutti L Abstract Immunotherapy is an emerging therapeutic strategy with a promising clinical outcome in some solid tumors, particularly metastatic melanoma. One approach to immunotherapy is immune checkpoint inhibitors, such as blockage of CTLA-4 and PD-1/PD-L1. This special report aims…
Read MoreAberrant Cytokeratin 20 Reactivity in Epithelioid Malignant Mesothelioma: A Case Report
Applied Immunohistochemistry and Molecular Morphology 2017 February [Epub ahead of print] [Link] Manur R, Lamzabi I Abstract Malignant mesothelioma is an uncommon neoplasm that should be distinguished from the more common pulmonary adenocarcinomas and other metastatic lesions. Although diagnosis is based on morphologic features, immunohistochemical stains such as Calretinin, WT-1, CK-5/6, D2-40, Ber-Ep4, and MOC-31…
Read MoreLarge primary pleural synovial sarcoma with severe dyspnea: a case report
Surgical Case Reports [Epub 2017 February 15] [Link] Yamaki M, Yonehara S, Noriyuki T Abstract BACKGROUND: Synovial sarcoma is a malignant neoplasm of soft tissues. It occurs mainly in the extremities and is closely related to tendons, tendon sheaths, and bursal structures. Primary synovial sarcoma of the pleura and lungs is extremely rare. CASE PRESENTATION:…
Read MoreMalignant pericardial mesothelioma : A systematic review of current practice
Herz 2017 January 27 [Epub ahead of print] [Link] Cao S, Jin S, Cao J, Shen J, Zhang H, Meng 1, Pan B, Yu Y. Abstract BACKGROUND: Malignant mesothelioma is a rare but aggressive tumor, with a high misdiagnosis rate and overall bleak prognosis. In 0.7% of all cases, the origin is the pericardium. METHODS:…
Read MoreMalignant Pleural Mesothelioma with Excessive Inflammation and High Level of Interleukin 6 – A Case Report
Cancer & Chemotherapy 2016 November [Link] Miura T, Iida , Igaki , Shiobara H, Matsumoto R, Mitachi K, Miyakawa T, Ohata Y, Saitou K, Irie T, Yamazaki S Abstract Malignant mesothelioma is a rare aggressive solid tumor that is invariably incurable. A 23-year-old female patient with ascites, anemia, and high levels of ferritin and CRP…
Read MorePeritoneal Deciduoid Mesothelioma
International Journal of Surgical Pathology 2017 January [Epub ahead of print] [Link] Dominiak N, Graybill W, Gunning W, Richardson MS, Spruill LS Abstract This report highlights a diagnostically challenging case of diffuse deciduoid mesothelioma occurring in the peritoneum of a 25-year-old woman, 8 months postpartum. Optimally debulked tumor consisted of sheets of polygonal cells arranged…
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