Lung Cancer
Inhibiting crosstalk between MET signaling and mitochondrial dynamics and morphology: a novel therapeutic approach for lung cancer and mesothelioma.
Cancer Biology & Therapy 2018 October 12 [Link] Wang J, Mirzapoiazova T, Carol Tan YH, Pang KM, Pozhitkov A, Wang Y, Wang Y, Mambetsariev B, Wang E, Nasser MW, Batra SK, Raz D, Reckamp K, Kulkarni P, Zheng Abstract The receptor tyrosine kinase MET is frequently involved in malignant transformation and inhibiting its activity in…
Read MoreInhibiting crosstalk between MET signaling and mitochondrial dynamics and morphology: a novel therapeutic approach for lung cancer and mesothelioma.
Cancer Biology and Therapy 2018 October 12 [Link] Wang J, Mirzapoiazova T, Carol Tan YH, Pang KM, Pozhitkov A, Wang Y, Wang Y, Mambetsariev B, Wang E, Nasser MW, Batra SK, Raz D, Reckamp K, Kulkarni P, Zheng Y Abstract The receptor tyrosine kinase MET is frequently involved in malignant transformation and inhibiting its activity…
Read MoreFour-miRNA signature to identify asbestos-related lung malignancies.
Cancer Epidemiology, Biomarkers, & Prevention 2018 September 26 [Link] Santarelli L, Gaetani S, Monaco F, Bracci M, Valentino M, Amati M, Rubini C, Sabbatini A, Pasquini E, Zanotta N, Comar M, Neuzil J, Tomasetti M, Bovenz Abstract BACKGROUND: Altered miRNA expression is an early event upon exposure to occupational/environmental carcinogens; thus, identification of a novel…
Read MoreNovel platinum agents and mesenchymal stromal cells for thoracic malignancies: state of the art and future perspectives.
Expert Opinion on Therapeutic Patents 2018 September 24 [Link Petrella F, Rimoldi I, Facchetti G, Spaggiari L Abstract Non-small cell lung cancer and malignant pleural mesothelioma represent two of the most intriguing and scrutinized thoracic malignancies, presenting interesting perspectives of experimental development and clinical applications. Areas covered: In advanced non-small cell lung cancer, molecular targeted…
Read MoreMortality in a cohort of asbestos-exposed workers undergoing health surveillance.
La Medicina del Lavoro 2018 February 6 [Link] Barbiero F, Zanin T, Pisa FE, Casetta A, Rosolen V, Giangreco M, Negro C, Bovenzi M, Barbone F Abstract BACKGROUND: The coastal area of Friuli Venezia Giulia (FVG) region, north-eastern Italy, was characterized by work activities in which asbestos was used until the early 1990s, particularly in…
Read MoreThe hippo pathway provides novel insights into lung cancer and mesothelioma treatment.
Journal of Cancer Research and Clinical Oncology 2018 August 3 [Link] Liu XL, Zuo R, Ou WB Abstract PURPOSE: Lung cancer and mesothelioma are two types of respiratory disease that have fatal courses and poor prognoses. Although a substantial number of targeted small molecules and antibody drugs have been developed, the 5-year survival rates of…
Read MoreThe characteristics of asbestos-related disease claims made to the Korea Workers’ Compensation and Welfare Service (KCOMWEL) from 2011 to 2015.
Annals of Occupational and Environmental Medicine 2018 July 11 [Link] An YS, Kim HD, Kim HC, Jeong KS, Ahn YS Abstract BACKGROUND: This study aimed to enhance understanding of the epidemiologic characteristics of asbestos-related diseases, and to provide information that could inform policy-making aimed at prevention and compensation for occupational asbestos exposure, through analyzing asbestos-related…
Read MoreMeasuring EMPs in the lung what can be measured in the lung: Asbestiform minerals and cleavage fragments.
Toxicology and Applied Pharmacology 2018 June 27 [Link] Roggli VL Abstract Asbestos mineral fibers have been associated with the development of a variety of diseases in humans and experimental animals, including asbestosis, lung cancer, and mesothelioma. Asbestos includes several mineral types divided into two mineral groups, serpentine and amphibole forms. Chrysotile is the serpentine mineral…
Read MoreCancer incidence in a cohort of asbestos-exposed workers undergoing health surveillance.
International Archives of Occupational and Environmental Health 2018 June 5 [Link] Barbiero F, Zanin T, Pisa FE, Casetta A, Rosolen V, Giangreco M, Negro C, Bovenzi M, Barbone F Abstract OBJECTIVES: To compare a local cohort of 2488 men occupationally exposed to asbestos and enrolled in a public health surveillance program with the 1995-2009 cancer…
Read MoreThe current aetiology of malignant pleural effusion in the Western Cape Province, South Africa
South African Medical Journal 2018 March 28 [Link] Koegelenberg CFN1, Bennji SM, Boer E, Schubert PT, Shaw JA, Allwood BW, Irusen EM Abstract BACKGROUND: Malignant pleural effusion (MPE) represents a very common cause of pleural exudates, and is one of the most challenging pleural disorders to manage. This could be attributed to the paucity of…
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