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Curated Journal Articles on Mesothelioma

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Loaction of the turmors and cell characteristics are among the differientiating factors in mesothelioma.

SMARCB1/INI1/BAF47- deficient pleural malignant mesothelioma with rhabdoid features

Pathology International 2018 January 5 [Epub ahead of print] [Link] Kimura N, Hasegawa M, Hiroshima K Abstract Malignant mesothelioma (MM) with rhabdoid features is an MM variant. Fifteen cases have been reported previously, all of which were combined with other types of MM. Herein, we report an autopsy case of pleural MM with monomorphic rhabdoid […]

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Germline and somatic variant identification using BGISEQ-500 and HiSeq X Ten whole genome sequencing

PloS one 2018 January [Link] Patch AM et. al. Abstract Technological innovation and increased affordability have contributed to the widespread adoption of genome sequencing technologies in biomedical research. In particular large cancer research consortia have embraced next generation sequencing, and have used the technology to define the somatic mutation landscape of multiple cancer types. These […]

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Nuclear grade and necrosis predict prognosis in malignant epithelioid pleural mesothelioma: a multi-institutional study

Modern Pathology 2018 January 12 [Epub ahead of print] [Link] Rosen LE et.al. Abstract A recently described nuclear grading system predicted survival in patients with epithelioid malignant pleural mesothelioma. The current study was undertaken to validate the grading system and to identify additional prognostic factors. We analyzed cases of epithelioid malignant pleural mesothelioma from 17 […]

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A Nomogram to Predict Prognosis in Malignant Pleural Mesothelioma

World Journal of Surgery 2017 December 28 [Epub ahead of print] [Link] Wang S, Ma K, Chen Z, Yang X, Sun F, Jin Y, Shi Y, Jiang W, Wang Q, Zhan C Abstract BACKGROUND: Malignant pleural mesothelioma (MPM) is a rare malignancy with heterogeneous outcomes. This study was aimed to develop a nomogram to precisely […]

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A genetic variant of NLRP1 gene is associated with asbestos body burden in patients with malignant pleural mesothelioma

Journal of Toxicology 2017 December [Epub ahead of print] [Link] Crovella S. et.al. Abstract The presence of asbestos bodies (ABs) in lung parenchyma is considered a histopathologic hallmark of past exposure to asbestos fibers, of which there was a population of longer fibers. The mechanisms underlying AB formation are complex, involving inflammatory responses and iron […]

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Asbestos fibre burden in gallbladder: A case study

Micron 2017 Dec 8 [Epub ahead of print] [Link] Croce A, Capella S, Belluso E, Grosso F, Mariani N, Libener R, Rinaudo C Abstract The methods conventionally used to determine the burden of asbestos fibres inhaled/incorporated in lung require chemical digestion of the biological matrix before counting/characterising the inorganic fibrous phases under scanning electron microscopy […]

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Difficulty in positive diagnosis of ascites and in differential diagnosis of a pulmonary tumor

Roman Journal of Morphology and Embryology 2017 [Link] ForĊ˘ofoiu MC Abstract Ascites is the most frequent complication of cirrhosis and occurs only when the portal hypertension has already installed but ascites is caused by neoplasms, heart failure, tuberculosis, pancreatic illnesses, as well as other kind of affections. We describe the case of a 67-year-old patient, […]

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Endoscopic ultrasound-guided fine-needle aspiration from ascites and peritoneal nodules: A scoping review

Endoscopic Ultrasound 2017 November-December [Link] Sharma V, Rana SS, Ahmed SU, Guleria S, Sharma R, Gupta R Abstract The peritoneum is involved in many diseases such as primary malignancy (mesothelioma), infectious disease (tuberculosis), and disseminated malignancy (peritoneal carcinomatosis). The peritoneal disease may manifest as ascites and/or peritoneal masses or nodules. Endoscopic ultrasound (EUS), due to […]

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Complement Protein C1q Binds to Hyaluronic Acid in the Malignant Pleural Mesothelioma Microenvironment and Promotes Tumor Growth

Frontiers in Immunology 2017 November [Link] Agostinis C et. al. Abstract C1q is the first recognition subcomponent of the complement classical pathway, which acts toward the clearance of pathogens and apoptotic cells. C1q is also known to modulate a range of functions of immune and non-immune cells, and has been shown to be involved in […]

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Breath analysis by gas chromatography-mass spectrometry and electronic nose to screen for pleural mesothelioma: a cross-sectional case-control study

Oncotarget 2017 September [Link] Lamote K, et. al Abstract RATIONALE: Malignant pleural mesothelioma (MPM) is mainly caused by previous exposure to asbestos fibers and has a poor prognosis. Due to a long latency period between exposure and diagnosis, MPM incidence is expected to peak between 2020-2025. Screening of asbestos-exposed individuals is believed to improve early […]

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