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Curated Journal Articles on Mesothelioma

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Loaction of the turmors and cell characteristics are among the differientiating factors in mesothelioma.

Upcoming epidemic of asbestos-related malignant pleural mesothelioma in Taiwan: A prediction of incidence in the next 30 years.

Journal of the Formosan Medical Association 2018 July 30 [Link] Lin RT, Chang YY, Wang JD, Lee LJ Abstract BACKGROUND/PURPOSE: Globally, asbestos-related diseases (ARDs) keep rising over the coming decades. The epidemic of ARDs will be a burden on public health. We aimed to predict the malignant pleural mesothelioma (MPM) incidence in the next 30 […]

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A polysome-based microRNA screen identifies miR-24-3p as a novel pro-migratory miRNA in mesothelioma.

Cancer Research 2018 August 2 [Link] Oliveto S, Alfieri R, Miluzio A, Scagliola A, Seclì RS, Gasparini P, Grosso S, Cascione L, Mutti L, Biffo S Abstract The expression of miRNAs in cancer has been widely studied and has allowed the definition of oncomirs and oncosuppressors. We note that it is often underestimated that many […]

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The hippo pathway provides novel insights into lung cancer and mesothelioma treatment.

Journal of Cancer Research and Clinical Oncology 2018 August 3 [Link] Liu XL, Zuo R, Ou WB Abstract PURPOSE: Lung cancer and mesothelioma are two types of respiratory disease that have fatal courses and poor prognoses. Although a substantial number of targeted small molecules and antibody drugs have been developed, the 5-year survival rates of […]

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Differential regulation of the sphere formation and maintenance of cancer-initiating cells of malignant mesothelioma via CD44 and ALK4 signaling pathways.

Oncogene 2018 Jul 30 [Link] Ohno Y, Shingyoku S, Miyake S, Tanaka A, Fudesaka S, Shimizu Y, Yoshifuji A, Yamawaki Y, Yoshida S, Tanaka S, Sakura K, Tanaka T Abstract Malignant mesothelioma (MM) has a poor prognosis and is largely resistant to standard treatments, so it is important to seek novel therapeutic strategies for this […]

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Utility of Methylthioadenosine Phosphorylase Compared With BAP1 Immunohistochemistry, and CDKN2A and NF2 Fluorescence In Situ Hybridization in Separating Reactive Mesothelial Proliferations From Epithelioid Malignant Mesotheliomas.

Archives of Pathology and Laboratory Medicine 2018 July 30 [Link] Berg KB, Dacic S, Miller C, Cheung S, Churg A Abstract CONTEXT: – The separation of reactive from malignant mesothelial proliferations is often a difficult morphologic problem. There is contradictory information in the literature on whether methylthioadenosine phosphorylase (MTAP) immunohistochemistry can be used for this […]

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A systematic review and meta-analysis of second-line therapies for treatment of mesothelioma.

Respiratory Medicine 2018 August [Link] Petrelli F, Ardito R, Conti B, Coinu A, Cabiddu M, Ghilardi M, Borgonovo K, Barni S, Ghidini Ah3>Abstract Malignant plINTRODUCTION: Advanced malignant pleural mesothelioma (MPM) is generally treated with platinum/pemetrexed-based first-line therapy. Once the disease progresses, evidence for the efficacy of palliative treatments is lacking, and platinum re-challenge or single-agent […]

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Mismatch repair protein defects and microsatellite instability in malignant pleural mesothelioma.

Journal of Thoracic Oncology 2018 July 26 [Link] Arulananda S, Thapa B, Walkiewicz M, Zapparoli GV, Williams DS, Dobrovic A, John T Abstract INTRODUCTION: Malignant pleural mesothelioma is an aggressive malignancy with limited systemic therapy options. Promising results have been reported with use of anti-PD-1 therapy, however it appears to be confined to a subgroup […]

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Dose-Dependent Effect of Red Blood Cells Transfusion on Perioperative and Long-Term Outcomes in Peritoneal Surface Malignancies Treated with Cytoreduction and HIPEC.

Annals of Surgical Oncology 2018 July 26 [Link] Nizri E, Kusamura S, Fallabrino G, Guaglio M, Baratti D, Deraco M Abstract BACKGROUND: Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) are associated with increased red blood cell transfusion (RBT) demand. Although the deleterious effects of RBT are documented in various settings, its effect in this […]

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A Clinical Trial of TumorGlow® to Identify Residual Disease during Pleurectomy and Decortication.

The Annals of Thoracic Surgery 2018 July 17 [Link] Predina JD, Newton AD, Corbett C, Xia L, Shin M, Sulfyok LF, Okusanya OT, Cengel KA, Haas A, Litzky L, Kucharczuk JC, Singhal S Abstract BACKGROUND: Macroscopic complete resection can provide a select group of malignant pleural mesothelioma (MPM) patients improved survival. During resection, differentiating residual […]

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A BILATERAL METACHRONOUS MESOTHELIOMA OF THE TUNICA VAGINALIS.

Urology 2018 July 17 [Link] Abello A, Steinkeler J, Das AK Abstract This is a unique case of bilateral metachronous testicular mesothelioma of the tunica vaginalis. Testicular mesothelioma is a rare entity found in patients with or without asbestos occupational exposure. The tumor most commonly presents as a unilateral testicular mass. More rare presentations include […]

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