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Curated Journal Articles on Mesothelioma

Category Archives: Serum Marker/Blood Test

Improved diagnosis and prognostication of patients with pleural malignant mesothelioma using biomarkers in pleural effusions and peripheral blood samples – a short report

Cell Oncology 2017 June 2 [Epub ahead of print] [Link] Beije N, Kraan J, den Bakker MA, Maat APWM, van der Leest C, Cornelissen R, Van NM, Martens JWM, Aerts JGJV, Sleijfer S Abstract PURPOSE: There is a lack of robust and clinically utilizable markers for the diagnosis and prognostication of malignant pleural mesothelioma (MPM). […]

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Glycodelin is a potential novel follow-up biomarker for malignant pleural mesothelioma

Oncotarget 2016 October 4 [Epub ahead of print] [Link] Schneider MA, Muley T, Kahn NC, Warth A, Thomas M, Herth FJ, Dienemann H, Meister M Abstract Malignant pleural mesothelioma (MPM) is a rare and aggressive tumor with a short survival time arising from the mesothelial cells of the pleura. Soluble mesothelin-related peptide (SMRP), osteopontin or […]

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Combination of onconase and dihydroartemisinin synergistically suppresses growth and angiogenesis of non-small-cell lung carcinoma and malignant mesothelioma

Acta Biochemica et Biophysica Sinica 2016 September 2 [Epub ahead of print] [Link] Shen R, Li J, Ye D, Wang Q, Fei J Abstract Onconase (Onc) is a cytotoxic ribonuclease derived from leopard frog oocytes or early embryos, and has been applied to the treatment of malignant mesothelioma in clinics. Onc also exhibits effective growth […]

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Prognostic value of several biomarkers for the patients with malignant pleural mesothelioma

Tumour Biology 2015 September11 [Epub ahead of print] [Link] Liu H, Wu L, Wang W. Abstract Malignant pleural mesothelioma (MPM) is a highly aggressive tumor of the pleura closely related to asbestos exposure. Rare as it is, the incidence of MPM is predicted to increase mainly as a result of a lengthy latency period from […]

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Mesothelin in Serum and Pleural Effusion in the Diagnosis of Malignant Pleural Mesothelioma with Non-positive Cytology

Anticancer Research 2014 December [Link] Franceschini MC, Ferro P, Canessa PA, Battolla E, Dessanti P, Valentino A, Casolari L, Fontana V, Pezzi R, Fedeli F, Pistillo MP, Roncella S. Abstract Background/Aim Mesothelin (SMRP) is regarded as a biomarker of malignant pleural mesothelioma (MPM). Herein, we analyzed the contribution of SMRP detection in pleural effusion and […]

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Combination of MiR-103a-3p and Mesothelin Improves the Biomarker Performance of Malignant Mesothelioma Diagnosis

PLoS One 2014 Dec 3 [Link] Weber DG, Casjens S, Johnen G, Bryk O, Raiko I, Pesch B, Kollmeier J, Bauer TT, Brüning T. Abstract Background For the detection of malignant mesothelioma no single biomarker with reasonable sensitivity and specificity has been described so far. Mesothelin, the most prominent blood-based biomarker, is characterized by high […]

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Expression of thrombomodulin, calretinin, cytokeratin 5/6, D2-40 and WT-1 in a series of primary carcinomas of the lung: an immunohistochemical study in comparison with epithelioid pleural mesothelioma

Tumori 2014 Sept-Oct [Link] Comin CE, Novelli L, Cavazza A, Rotellini M, Cianchi F, Messerini L. Abstract Aims and Background A number of immunohistochemical markers have been suggested as useful in the positive diagnosis of epithelioid mesothelioma. The most widely used mesothelioma markers are thrombomodulin, calretinin, cytokeratin 5/6, D2-40 and WT-1. Numerous investigations have demonstrated […]

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A serum mesothelin level is a prognostic indicator for patients with malignant mesothelioma in routine clinical practice

BMC Cancer. 2014 September 17 [Epub ahead of print] [Link] Linch M, Gennatas S, Kazikin S, Iqbal J, Gunapala R, Priest K, Severn J, Norton A, Ayite B, Bhosle J, O Brien M, Popat S. Abstract Background Malignant mesothelioma (MM) carries a poor prognosis and response rates to palliative chemotherapy remain low. Identifying patients with […]

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Comparison of fibulin-3 and mesothelin as markers in malignant mesothelioma

Thorax. 2014 July 18. [Epub ahead of print] [Link] Creaney J, Dick IM, Meniawy TM, Leong SL, Leon JS, Demelker Y, Segal A, Bill Musk AW, Lee YC, Skates SJ, Nowak AK, Robinson BW. Abstract Background Pleural malignant mesothelioma (MM) is a deadly tumour predominantly associated with asbestos exposure. A reliable diagnostic and prognostic marker […]

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The utility of serum N-ERC/mesothelin as a biomarker of ovarian carcinoma

Oncology Letters.. 2012 Oct;4(4):637-641. Epub 2012 Jul 11. [Link] Saeki H, Hashizume A, Izumi H, Suzuki F, Ishi K, Nojima M, Maeda M, Hino O. Departments of Diagnostic Pathology. Abstract Ovarian carcinoma has been difficult to diagnose at an early stage. Recently, it has been recognized that the measurement of blood N-ERC/mesothelin levels aids early […]

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