Screening of Pleural Mesotheliomas for DNA-damage Repair Players by Digital Gene Expression Analysis Can Enhance Clinical Management of Patients Receiving Platin-Based Chemotherapy

October 9, 2016

Journal of Cancer 2016 September 13 [Link] Walter RF, Vollbrecht C, Werner R, Mairinger T, Schmeller J, Flom E, Wohlschlaeger J, Barbetakis N, Paliouras D, Chatzinikolaou F, Adamidis V, Tsakiridis K, Zarogoulidis P, Trakada G, Christoph DC, Schmid KW, Mairinger FD Abstract BACKGROUND: Malignant pleural mesothelioma (MPM) is a rare, predominantly asbestos-related and biologically highly…

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The IASLC Mesothelioma Staging Project: Proposals for the M Descriptors and for Revision of the TNM Stage Groupings in the Forthcoming (Eighth) Edition of the TNM Classification for Mesothelioma

October 6, 2016

Journal of Thoracic Oncology 2016 September 27 [Epub ahead of print] [Link] Rusch VW, Chansky K, Kindler HL, Nowak AK, Pass HI, Rice DC, Shemanski L, Galateau-Sallé F, McCaughan BC, Nakano T, Ruffini E, van Meerbeeck JP, Yoshimura M; Staging and Prognostic Factors Committee, Advisory Boards and Participating Institutions Abstract INTRODUCTION: The metastasis (M) component…

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The IASLC Mesothelioma Staging Project: Proposals for Revisions of the T descriptors in the forthcoming Eighth edition of the TNM classification for pleural mesothelioma

October 5, 2016

Journal of Thoracic Oncology 2016 September 23 [Epub ahead of print] [Link] Nowak AK, Chansky K, Rice DC, Pass HI, Kindler HL, Shemanski L, Billé A, Rintoul R, Batirel HF, Thomas CF, Friedberg J, Cedres S, de Perrot M, Rusch VW; Staging and Prognostic Factors Committee, Advisory Boards and Participating Institutions Abstract INTRODUCTION: Current T…

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The IASLC Mesothelioma Staging Project: Proposals for Revisions of the N Descriptors in the Forthcoming Eighth Edition of the TNM Classification for Pleural Mesothelioma

October 4, 2016

Journal of Thoracic Oncology 2016 September 23 [Epub ahead of print] [Link] Rice D, Chansky K, Nowak A, Pass H, Kindler H, Shemanski L, Opitz I, Caja SC, Hasegawa S, Kernstine K, Atinkaya C, Rea F, Nafteux P, Rusch V; Staging and Prognostic Factors Committee, Advisory Boards and Participating Institutions Abstract INTRODUCTION: Nodal categories for…

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Combination of onconase and dihydroartemisinin synergistically suppresses growth and angiogenesis of non-small-cell lung carcinoma and malignant mesothelioma

September 6, 2016

Acta Biochemica et Biophysica Sinica 2016 September 2 [Epub ahead of print] [Link] Shen R, Li J, Ye D, Wang Q, Fei J Abstract Onconase (Onc) is a cytotoxic ribonuclease derived from leopard frog oocytes or early embryos, and has been applied to the treatment of malignant mesothelioma in clinics. Onc also exhibits effective growth…

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Arginine Deprivation With Pegylated Arginine Deiminase in Patients With Argininosuccinate Synthetase 1-Deficient Malignant Pleural Mesothelioma: A Randomized Clinical Trial

September 3, 2016

JAMA Oncology 2016 September 1 [Epub ahead of print] [Link] Szlosarek PW, Steele JP, Nolan L, Gilligan D, Taylor P, Spicer J, Lind M, Mitra S, Shamash J, Phillips MM, Luong P, Payne S, Hillman P, Ellis S, Szyszko T, Dancey G, Butcher L, Beck S, Avril NE, Thomson J, Johnston A, Tomsa M, Lawrence…

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Malignant pleural fluid from mesothelioma has potent biological activities

September 1, 2016

Respirology 2016 August 25 [Epub ahead of print] [Link] Cheah HM, Lansley SM, Varano Della Vergiliana JF, Tan AL, Thomas R1, Leong SL, Creaney J, Lee YC Abstract BACKGROUND AND OBJECTIVE: Malignant pleural effusion (MPE) affects >90% of mesothelioma patients. Research on MPE has focused on its physical impact on breathlessness; MPE is rich in…

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