Pleural Effusion
[Primary pleural epithelioid hemangioendothelioma, an often-misdiagnosed rare tumor]
Revue des Maladies Respiratoires 2022 April [Link] P Tossan, E Pichon, F Arbion, D Sizaret, G Simionca, S Marchand-Adam Abstract Introduction: Epithelioid hemangioendothelioma (EHE) is a rare vascular tumor that develops in various organs. Primary pleural epithelioid hemangioendothelioma is an exceptional occurrence, with only forty cases reported in the literature. On account of its rarity,…
Read MoreEvaluation of DNA/RNA quality from cell block of malignant mesothelioma and lung adenocarcinoma
Diagnostic Cytopathology 2022 April 5 [Link] Shigenobu Tatsumi, Mao Takeuchi, Tomomi Fujii, Aya Sugimoto, Yoko Sekita-Hatakeyama, Takeshi Nishikawa, Tomoko Uchiyama, Kohei Morita, Hiroe Itami, Maiko Takeda, Masaharu Yamazaki, Chiho Ohbayashi Abstract Malignant mesothelioma (MM) is a rare and highly lethal tumor that arises from mesothelial tissue on the surface of the chest and abdominal cavity.…
Read MoreECM Mechanoregulation in Malignant Pleural Mesothelioma
Frontiers in Bioengineering and Biotechnology 2022 February 14 [Link] Valeria Panzetta, Ida Musella, Sabato Fusco, Paolo A Netti Abstract Malignant pleural mesothelioma is a relatively rare, but devastating tumor, because of the difficulties in providing early diagnosis and effective treatments with conventional chemo- and radiotherapies. Patients usually present pleural effusions that can be used for…
Read MorePrognostic Impact of Pleural Effusion in Patients with Malignancy: A Systematic Review and Meta-Analysis
Clinical and Translational Science 2022 February 25 [Link] Yuan Yang, Juan Du, Yi-Shan Wang, Han-YuJie Kang, Kan Zhai, Huan-Zhong Shi Abstract The exact role of pleural effusion in the prognosis of cancer patients remains unclear. We aimed to systematically review the prognostic value of pleural effusion in cancer patients. We performed a systematic review and…
Read MoreEvaluation of pleural fluid cytology for the diagnosis of malignant pleural effusion: a retrospective cohort study
Internal Medicine Journal 2022 February 21 [Link] L Pairman, Lel Beckert, M Dagger, M J Maze Abstract Background: Cytological examination of pleural fluid has a good specificity but imperfect sensitivity for the diagnosis of malignant pleural effusion (MPE). Published estimates of sensitivity vary and predictors of false negative cytology are not well established. We aimed…
Read MoreImage-guided interventional radiological delivery of chimeric antigen receptor (CAR) T cells for pleural malignancies in a phase I/II clinical trial
Lung Cancer 2022 January 6 [Link] Mario Ghosn, Waseem Cheema, Amy Zhu, Jennifer Livschitz, Majid Maybody, Franz E Boas, Ernesto Santos, DaeHee Kim, Jason A Beattie, Michael Offin, Valerie W Rusch, Marjorie G Zauderer, Prasad S Adusumilli, Stephen B Solomon Abstract Objectives: We describe techniques and results of image-guided delivery of mesothelin-targeted chimeric antigen receptor…
Read MoreDiagnostic method for malignant pleural effusion distinguishing malignant mesothelioma from lung cancer using pleural carcinoembryonic antigen and hyaluronic acid levels
Medicine 2022 January 7 [Link] Takeshi Saraya, Kosuke Ohkuma, Masachika Fujiwara, Haruyuki Ishii Abstract Malignant mesothelioma (MM) is difficult to diagnose because of the lack of parenchymal opacities, often revealing minimal or absent pleural thickening. Furthermore, pleural effusion has diverse differential diagnoses, including malignancies, infections, as well as collagen vascular and other benign diseases. In…
Read MoreThe highlights of the 15th international conference of the international mesothelioma interest group – Do molecular concepts challenge the traditional approach to pathological mesothelioma diagnosis?
Lung Cancer 2021 November 6 [Link] Sonja Klebe, Francoise Galateau Salle, Rossella Bruno, Luka Brcic, Heather I Chen-Yost, Marie-Claude Jaurand Abstract Pathology plays an important role in diagnosing mesothelioma since radiological and clinical findings alone cannot distinguish mesothelioma reliably from its many mimics. The long-held gold standard for pathological diagnosis requires a tissue biopsy that,…
Read MoreRadical extrapleural pneumonectomy with bronchial fistula by pulmonary function test evaluation technique
Annals of Medicine and Surgery 2021 November 16 [Link] Saeid Marzban-Rad, Rama Bozorgmehr, Parastesh Sattari, Ghasem Azimi, Ali Azimi Abstract Introduction: and importance: Pulmonary Function Tests (PFTS) is an important tool in the assessment of pulmonary pathologies and preoperative evaluation. Case presentation: A 54-year-old man with history of massive pleurisy in the left thorax, treated…
Read MoreCytological Diagnostic Procedures in Malignant Mesothelioma
Advances in Experimental Medicine and Biology 2021 November 18 [Link] Christian Biancosino, Lea Isabell Shari van der Linde, Guido Sauter, Florian Stellmacher, Marcus Krüger, Lutz Welker Abstract Malignant mesotheliomas (MM) are rare tumors with high mortality rates, whose incidence varies regionally and nationally, and the diagnosis is difficult. Histology-based diagnosis is considered the gold standard…
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