The diagnostic value of Ki-67 and repp86 in distinguishing between benign and malignant mesothelial proliferations

Archives of Pathology and Laboratory Medicine. 2008 Apr;132(4):694-7. [Link] Taheri ZM, Mehrafza M, Mohammadi F, Khoddami M, Bahadori M, Masjedi MR. National Research Institute of Tuberculosis and Lung Disease, Department of Pathology, Shahid Beheshti University of Medical Sciences, Tehran, Iran. mtaheri@nritld.ac.ir Abstract Context: The differentiation of benign mesothelial proliferations from malignant mesotheliomas may be difficult,…

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MESOMARK kit detects C-ERC/mesothelin, but not SMRP with C-terminus

Biochemical and Biophysical Research Communications. 2008 May 9;369(3):915-8. Epub 2008 Mar 5. [Link] Segawa T, Hagiwara Y, Ishikawa K, Aoki N, Maeda M, Shiomi K, Hino O. Immuno-Biological Laboratories Co. Ltd., 5-1 Aramachi, Takasaki, Gunma 370-0831, Japan. Abstract ERC/mesothelin is expressed on the normal mesothelium and some cancers such as mesothelioma or ovarian carcinoma. A…

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Improved identification of malignant cells in serous effusions using a small, robust panel of antibodies on paraffin-embedded cell suspensions

Acta Cytologica. 2008 Jan-Feb;52(1):35-44. [Link] Grefte JM, de Wilde PC, Salet-van de Pol MR, Tomassen M, Raaymakers-van Geloof WL, Bulten J. Department of Pathology, University Medical Center Nijmegen, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands. a.grefte@pathol.umcn.nl Abstract Objective: To evaluate the expression of these markers individually and to find out which markers would be…

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tive and Specific New Enzyme-Linked Immunosorbent Assay for N-ERC/Mesothelin Increases its Potential as a Useful Serum Tumor Marker for Mesothelioma

Clinical Cancer Research. 2008 Mar 1;14(5):1431-7. [Link] Shiomi K, Hagiwara Y, Sonoue K, Segawa T, Miyashita K, Maeda M, Izumi H, Masuda K, Hirabayashi M, Moroboshi T, Yoshiyama T, Ishida A, Natori Y, Inoue A, Kobayashi M, Sakao Y, Miyamoto H, Takahashi K, Hino O. Authors’ Affiliations: Department of General Thoracic Surgery, Respiratory Medicine, Human…

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New diagnostic markers for malignant pleural mesothelioma

Bulletin du Cancer. 2008 Feb;95(2):177-84. [Link] Grigoriu BD, Grégoire M, Chahine B, Scherpereel A. Inserm U774, Institut Pasteur, Lille, France. Abstract The increasing number of malignant pleural mesothelioma (MPM) is a serious public health problem. The prognosis of this tumor is poor and most of the patients are diagnosed late in the disease’s course when…

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Establishment of a novel specific ELISA system for rat N- and C-ERC/mesothelin. Rat ERC/mesothelin in the body fluids of mice bearing mesothelioma

Cancer Science. 2008 Feb 24 [Epub ahead of print] [Link] Hagiwara Y, Hamada Y, Kuwahara M, Maeda M, Segawa T, Ishikawa K, Hino O. Immuno-Biological Laboratories, 5-1 Aramachi, Takasaki-Shi, Gunma 370-0831, Japan. Abstract Mesothelioma is a type of malignant tumor that most commonly arises from the pleural or peritoneal membrane and is usually associated with…

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Mesothelin-related predictive and prognostic factors in malignant mesothelioma: A nested case–control study

Lung Cancer. 2008 Feb 15 [Epub ahead of print] [Link] Roe OD, Creaney J, Lundgren S, Larsson E, Sandeck H, Boffetta P, Nilsen TI, Robinson B, Kjaerheim K. Department of Oncology, St. Olavs Hospital, Trondheim University Hospital, Norway; Norwegian University of Science and Technology (NTNU), Department of Cancer Research and Molecular Medicine, Trondheim, Norway. Abstract…

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PTEN expression is a strong predictor of survival in mesothelioma patients

European Journal of Cardiothoracic Surgery. 2008 Mar;33(3):502-6. Epub 2008 Jan 8. [Link] Opitz I, Soltermann A, Abaecherli M, Hinterberger M, Probst-Hensch N, Stahel R, Moch H, Weder W. Division of Thoracic Surgery, University Hospital Zurich, Rämistrasse 100, 8091 Zurich, Switzerland. Abstract Background: Malignant pleural mesothelioma (MPM) is a highly aggressive tumour with poor prognosis and…

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Profiling tumor-associated markers for early detection of malignant mesothelioma: an epidemiologic study

Cancer Epidemiology Biomarkers & Prevention. 2008 Jan;17(1):163-70. [Link] Amati M, Tomasetti M, Scartozzi M, Mariotti L, Alleva R, Pignotti E, Borghi B, Valentino M, Governa M, Neuzil J, Santarelli L. Department of Molecular Pathology and Innovative Therapies, Polytechnic University of Marche, via Tronto 10/A, Torrette di Ancona, 60020 Ancona, Italy. m.tomasetti@univpm.it. Abstract Improved detection methods…

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