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Mesothelioma-Line

Curated Journal Articles on Mesothelioma

Category Archives: Lung Cancer

Cancer incidence in a cohort of asbestos-exposed workers undergoing health surveillance.

International Archives of Occupational and Environmental Health 2018 June 5 [Link] Barbiero F, Zanin T, Pisa FE, Casetta A, Rosolen V, Giangreco M, Negro C, Bovenzi M, Barbone F Abstract OBJECTIVES: To compare a local cohort of 2488 men occupationally exposed to asbestos and enrolled in a public health surveillance program with the 1995-2009 cancer […]

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The current aetiology of malignant pleural effusion in the Western Cape Province, South Africa

South African Medical Journal 2018 March 28 [Link] Koegelenberg CFN1, Bennji SM, Boer E, Schubert PT, Shaw JA, Allwood BW, Irusen EM Abstract BACKGROUND: Malignant pleural effusion (MPE) represents a very common cause of pleural exudates, and is one of the most challenging pleural disorders to manage. This could be attributed to the paucity of […]

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Survivin is a negative prognostic factor in malignant pleural effusion

European Journal of Clinical Investigation 2018 January 23 [Epub ahead of print] [Link] Arellano-Orden E et. al. Abstract SURVIVIN: is a well-known member of the inhibitor of apoptosis family, and has been related with increased tumour aggressivity, both in tissue and in pleural fluid. OBJECTIVES: In patients with malignant pleural effusion, we sought to investigate […]

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Content validity and electronic PRO (ePRO) usability of the Lung Cancer Symptom Scale-Mesothelioma (LCSS-Meso) in mesothelioma patients

Supportive Care In Cancer 2018 February [Epub ahead of print] [Link] Gelhorn H et. al. Abstract PURPOSE: Obtaining qualitative data directly from the patient perspective enhances the content validity of patient-reported outcome (PRO) instruments. The objective of this qualitative study was to evaluate the content validity of the Lung Cancer Symptom Scale for Mesothelioma (LCSS-Meso) […]

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Progress in the Management of Advanced Thoracic Malignancies in 2017

Journal of Thoracic Oncology 2018 January 10 [Epub ahead of print] [Link] Ferrara R, Mezquita L, Besse B Abstract The treatment paradigm of non-small cell lung cancer (NSCLC) underwent a major revolution during the course of 2017. Immune checkpoint inhibitors (ICIs) brought remarkable improvements in response and overall survival (OS) both in unselected pretreated patients […]

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Chimeric antigen receptor (CAR) T-cell therapy for thoracic malignancies

Journal of Thoracic Oncology 2017 October [Epub ahead of print] [Link] Kiesgen S, Chicaybam L, Chintala NK, Adusumilli PS Abstract Chimeric antigen receptor (CAR) T cells are patient T cells that are transduced with genetically engineered synthetic receptors to target a cancer cell surface antigen. The remarkable clinical response rates achieved by adoptive transfer of […]

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Multicentric initial experience with the use of the pressurized intraperitoneal aerosol chemotherapy (PIPAC) in the management of unresectable peritoneal carcinomatosis

European Journal of Surgical Oncology 2017 September [Epub ahead of print] [Link] Alyami M, Gagniere J, Sgarbura O, Cabelguenne D, Villeneuve L, Pezet D, Quenet F, Glehen O, Bakrin N, Passot G Abstract BACKGROUND: PIPAC is a recent approach for intraperitoneal chemotherapy with promising results for patients with peritoneal carcinomatosis (PC). We aimed to evaluate […]

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The PD-L1/PD-1 pathway promotes dysfunction, but not “exhaustion”, in tumor-responding T cells from pleural effusions in lung cancer patients

Cancer Immunology, immunotherapy [Epub 2017 March 13] [Link] Prado-Garcia H, Romero-Garcia S, Puerto-Aquino A, Rumbo-Nava U Abstract Malignant pleural effusions are frequent in patients with advanced stages of lung cancer and are commonly infiltrated by lymphocytes and tumor cells. CD8+ T cells from these effusions have reduced effector functions. The programmed death receptor 1(PD-1)/programmed death […]

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Italian pool of asbestos workers cohorts: mortality trends of asbestos-related neoplasms after long time since first exposure

Occupational and Environmental Medicine 2017 August [Epub ahead of print] [Link] Ferrante D, et.al. Abstract OBJECTIVE: Asbestos is a known human carcinogen, with evidence for malignant mesothelioma (MM), cancers of lung, ovary, larynx and possibly other organs. MM rates are predicted to increase with a power of time since first exposure (TSFE), but the possible […]

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Diagnostic value of medical thoracoscopy in malignant pleural effusion

BMC Pulmonary Medicine 2017 August [Link] Wu YB, Xu LL, Wang XJ, Wang Z, Zhang J, Tong ZH, Shi HZ Abstract BACKGROUND: Medical thoracoscopy has been shown to be an efficacious procedure in diagnosing unexplained exudative pleural effusions with excellent safety. This study aimed to assess the diagnostic significance of thoracoscopy in the management of […]

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