MesotheliomaCenter's

Mesothelioma-Line

Curated Journal Articles on Mesothelioma

Category Archives: Lung Cancer

A prospective observational study of on-treatment plasma homocysteine levels as a biomarker of toxicity, depression and vitamin supplementation lead-in time pre pemetrexed, in patients with non-small cell lung cancer and malignant mesothelioma.

PloS One 2019 November 25 [Link] Minchom A, Mak D, Gunapala R, Walder D, Kumar R, Yousaf N, Hodgkiss A, Bhosle J, Popat S, O’Brien MER Abstract OBJECTIVES: Vitamin supplementation reduces pemetrexed toxicity. Raised plasma homocysteine reflects deficiency in vitamin B12 and folate, and is suppressed by supplementation. This observational study of 112 patients receiving […]

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Pleural mesothelioma and lung cancer: the role of asbestos exposure and genetic variants in selected iron metabolism and inflammation genes.

Journal of Toxicology and Environmental Health 2019 November 22 [Link] Celsi F, Crovella S, Moura RR, Schneider M, Vita F, Finotto L, Zabucchi G, Zacchi P, Borelli V Abstract Two of the major cancerous diseases associated with asbestos exposure are malignant pleural mesothelioma (MPM) and lung cancer (LC). In addition to asbestos exposure, genetic factors […]

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Secretome of pleural effusions associated with non-small cell lung cancer (NSCLC) and malignant mesothelioma: therapeutic implications.

Oncotarget 2019 November 5 [Link] Donnenberg AD, Luketich JD, Donnenberg VS Abstract INTRODUCTION: We compared the secretome of metastatic (non-small cell lung cancer (NSCLC)) and primary (mesothelioma) malignant pleural effusions, benign effusions and the published plasma profile of patients receiving chimeric antigen receptor T cells (CAR-T), to determine factors unique to neoplasia in pleural effusion […]

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Elevated Circulating Activin A Levels in Patients With Malignant Pleural Mesothelioma Are Related to Cancer Cachexia and Reduced Response to Platinum-based Chemotherapy.

Clinical Lung Cancer 2019 October 25 [Link] Paajanen J, Ilonen I, Lauri H, Järvinen T, Sutinen E, Ollila H, Rouvinen E, Lemström K, Räsänen J, Ritvos O, Koli K, Myllärniemi M Abstract BACKGROUND: Previous preclinical studies have shown that activin A is overexpressed in malignant pleural mesothelioma (MPM), associates with cancer cachexia, and is observed […]

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Why Be One Protein When You Can Affect Many? The Multiple Roles of YB-1 in Lung Cancer and Mesothelioma.

Frontiers in Cell and Developmental Biology 2019 October 1 [Link] Johnson TG, Schelch K, Mehta S, Burgess A, Reid G Abstract Lung cancers and malignant pleural mesothelioma (MPM) have some of the worst 5-year survival rates of all cancer types, primarily due to a lack of effective treatment options for most patients. Targeted therapies have […]

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Survival in patients with malignant pleural effusion undergoing talc pleurodesis.

Lung Cancer 2019 September 4 [Link] Hassan M1, Mercer RM2, Maskell NA3, Asciak R2, McCracken DJ, Bedawi EO, Shaarawy H, El-Ganady A, Psallidas I, Miller RF, Rahman NM Abstract OBJECTIVES: Recent observations indicate a potential survival benefit in patients with malignant pleural effusion (MPE) who achieve successful pleurodesis in comparison to patients who experience effusion […]

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Analyzing biological and molecular characteristics and genomic damage induced by exposure to asbestos.

Cancer Management and Research 2019 May 30 [Link] Ospina D, Villegas VE, Rodríguez-Leguizamón G, Rondón-Lagos M Abstract Asbestos is one of the most important occupational carcinogens. Currently, about 125 million people worldwide are exposed to asbestos in the workplace. According to global estimates, at least 107,000 people die each year from lung cancer, mesothelioma, and […]

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An asbestos contaminated town in the vicinity of an asbestos-cement facility: The case study of Sibaté, Colombia.

Environmental Research 2019 May 6 [Link] Ramos-Bonilla JP, Cely-García MF, Giraldo M, Comba P, Terracini B, Pasetto R, Marsili D, Ascoli V, Lysaniuk B, Rodríguez MC, Mazzeo A, Panqueva RDPL, Baldión M, Cañón D, García-Herreros LG, Pinzón B, Hernández LJ, Silva YA Abstract INTRODUCTION: The asbestos industry began operations in Colombia in 1942, with an […]

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Risk of mesothelioma after cessation of asbestos exposure: a systematic review and meta-regression.

International Archives of Occupational and Environmental Health 2019 April 15 [Link] Boffetta P, Donato F, Pira E, Luu HN, La Vecchia C Abstract PURPOSE: A ‘risk reversal’ has been observed for several human carcinogens following cessation of exposure, but it is unclear whether it also exists for asbestos-related mesothelioma. METHODS: We conducted a systematic review […]

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Asbestosis and silicosis hospitalizations in Italy (2001-2015): results from the National Hospital Discharge Registry.

European Journal of Public Health 2019 February 7 [Link] Ferrante P Abstract BACKGROUND: This work is aimed at evaluating the quality of Italian hospitalizations data about asbestosis and silicosis, assessing the impact of these diseases on the national health system and providing advice related to public health. METHODS: Italian hospital discharge data (2001-15) with diagnosis […]

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