Pleural
Patients with mesothelioma and their carer’s experience of diet and appetite: A qualitative insight from the Help-Meso Study
Journal of Human Nutrition and Dietetics 2024 April 7 [Link] Lorelle L Dismore, Leah L Taylor, Avinash Aujayeb, Christopher Hurst, Katherine Swainston Abstract Background: People living with mesothelioma have a high symptom burden that can affect dietary intake and the development of malnutrition, subsequently impacting on patient-related and treatment outcomes. The present study aimed to…
Read MoreEstablishing mesothelioma patient-derived organoid models from malignant pleural effusions
Lung Cancer 2024 March 28 [Link] Ashleigh J Hocking, Lauren A Mortimer, Alexandra L Farrall, Prudence A Russell, Sonja Klebe Abstract Objectives: Pleural mesothelioma is a cancer arising in the cells that line the lungs and chest wall with poor survival and poor response to first-line therapy. Organoid models of cancer can faithfully recapitulate the…
Read MorePleural mesothelioma in situ: a comprehensive review
European Journal of Cancer Prevention 2024 March 11 [Link] Federica Danuzzo, Federico Raveglia, Francesca Spinelli, Chiara Maria Sibilia, Enrico Cassina, Lidia Libretti, Emanuele Pirondini, Antonio Tuoro, Francesca Bono, Maria Emilia Paladino, Diego Cortinovis, Francesco Petrella Abstract Pleural mesothelioma is a rare and aggressive cancer that affects the pleura. In recent years, there has been increasing…
Read MoreKinetically Controlled Polyelectrolyte Complex Assembly of microRNA-Peptide Nanoparticles toward Treating Mesothelioma
Advanced Materials 2024 March 26 [Link] Caleb F Anderson, Anand Singh, Tyler Stephens, Chuong D Hoang, Joel P Schneider Abstract Broad size distributions and poor long-term colloidal stability of microRNA-carrying nanoparticles, especially those formed by polyelectrolyte complexation, represent major hurdles in realizing their clinical translation. Herein, peptide design is used alongside optimized flash nanocomplexation (FNC)…
Read MoreCharacterization of pleural mesothelioma by hierarchical clustering analyses using immune cells within tumor microenvironment
Pathobiology 2024 March 25 [Link] Shingo Inaguma, Chengbo Wang, Sunao Ito, Akane Ueki, Jerzy Lasota, Piotr Czapiewski, Renata Langfort, Janusz Rys, Joanna Szpor, Piotr Waloszczyk, Krzysztof Okoń, Wojciech Biernat, Shuji Takiguchi, David S Schrump, Markku Miettinen, Satoru Takahashi Abstract Introduction: Over the past decade, classifications using immune cell infiltration have been applied to many types…
Read MoreThe mental health and well-being implications of a mesothelioma diagnosis: A mixed methods study
European Journal of Oncology Nursing 2024 March 15 [Link] Virginia Sherborne, Emily Wood, Catriona R Mayland, Clare Gardiner, Caitlin Lusted, Anna Bibby, Angela Tod, Bethany Taylor, Stephanie Ejegi-Memeh Abstract Purpose: Mesothelioma is an incurable, asbestos-related cancer with a poor prognosis. There is scant evidence about the mental health and well-being impacts on patients and carers…
Read MoreCombination of EZH2 and ATM inhibition in BAP1-deficient mesothelioma
British Journal of Cancer 2024 March 22 [Link] Nick Landman, Danielle Hulsman, Jitendra Badhai, Jawahar Kopparam, Julian Puppe, Gaurav Kumar Pandey, Maarten van Lohuizen Abstract Background: More than half of mesothelioma tumours show alterations in the tumour suppressor gene BAP1. BAP1-deficient mesothelioma is shown to be sensitive to EZH2 inhibition in preclinical settings but only…
Read MoreThe IASLC Mesothelioma Staging Project: Proposals for Revisions of the ‘T’ Descriptors in the Forthcoming 9th Edition of the TNM Classification for Pleural Mesothelioma
Journal of Thoracic Oncology 2024 March 21 [Link] Ritu R Gill, Anna K Nowak, Dorothy J Giroux, Megan Eisele, Adam Rosenthal, Hedy Kindler, Andrea Wolf, Robert T Ripley, Andre Billé, David Rice, Isabelle Opitz, Andreas Rimner, Marc dePerrot, Harvey I Pass, Valerie W Rusch; IASLC Staging and Prognostic Factors Committee; Advisory Boards and Participating Institution…
Read MoreReliably making the primary diagnosis of mesothelioma utilizing serous fluid cytology specimens: an institutional experience
Journal of the American Society of Cytopathology 2024 March 2 [Link] Terri E Jones, Daniel L Geisler, Swikrity Upadhyay Baskota, N Paul Ohori, Jacqueline Cuda, Samer N Khader Abstract Introduction: The diagnosis of mesothelioma has historically been challenging, especially on serous fluid cytology (SFC). Distinguishing between reactive and neoplastic mesothelial cells can be difficult on…
Read MoreInvestigation of the appropriate viscosity of fibrinogen in repairing pleural defects using ventilation and anchoring in an ex vivo pig model
Journal of Cardiothoracic Surgery 2024 March 21 [Link] Akihiro Fukuda, Masaki Hashimoto, Yoshitaka Takegawa, Nobuyuki Kondo, Seiki Hasegawa Abstract Objective: Our previous study revealed that the viscosity of fibrinogen could influence the effectiveness of ventilation and anchoring (V/A) methods for controlling air leakages. Here, we examined the association between the viscosity of fibrinogen and effectiveness…
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