Intrapleural Chemotherapy
A pharmacologic analysis of intraoperative intracavitary cancer chemotherapy with doxorubicin
Cancer Chemotherapy and Pharmacology. 2008 Jul 25. [Epub ahead of print] [Link] Van der Speeten K, Stuart OA, Mahteme H, Sugarbaker PH. Department of Surgical Oncology, Ziekenhuis Oost-Limburg, Schiepse Bos 6, 3600, Genk, Belgium, kurt.vanderspeeten@zol.be. Abstract Purpose: A pharmacologic analysis of intracavitary doxorubicin in the treatment of patients with intracavitary cancer dissemination was performed to…
Read MorePiroxicam and intracavitary platinum-based chemotherapy for the treatment of advanced mesothelioma in pets: preliminary observations
Journal of Experimental and Clinical Cancer Research. 2008 May 19;27(1):6. [Link] Spugnini EP, Crispi S, Scarabello A, Caruso G, Citro G, Baldi A. S,A,F,U, Department, Regina Elena Cancer Institute -, Rome -, Italy. info@enricospugnini.net. Abstract Malignant Mesothelioma is an uncommon and very aggressive tumor that accounts for 1% of all the deaths secondary to malignancy…
Read MoreInduction of apoptosis by intrapleural perfusion hyperthermo-chemotherapy for malignant pleural mesothelioma
Annals of Thoracic and Cardiovascular Surgery. 2008 Jun;14(3):161-5. [Link] Matsuzaki Y, Tomita M, Shimizu T, Hara M, Ayabe T, Onitsuka T. Department of Surgery, Cardiovascular, Thoracic and General Surgery, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan. Abstract Purpose: Despite extensive clinical research, no effective therapy for advanced malignant pleural mesothelioma has been established. In…
Read MoreSurgical Treatment in the Management of Malignant Pleural Mesothelioma: A Single Institution’s Experience
Annals of Surgical Oncology. 2008 Jun;15(6):1757-64. Epub 2008 Apr 9 [Link] van Sandick JW, Kappers I, Baas P, Haas RL, Klomp HM. Department of Surgical Oncology, The Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands. j.v.sandick@nki.nl Abstract Background: A minority of patients with malignant pleural mesothelioma (MPM) are considered for…
Read MoreAnesthetic management of patients undergoing extrapleural pneumonectomy for mesothelioma
Current Opinion in Anaesthesiology. 2008 Feb;21(1):21-27. [Link] Ng JM, Hartigan PM. Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women’s Hospital, USA; Harvard Medical School, Boston, Massachusetts, USA. Abstract Purpose of review: Extrapleural pneumonectomy is a radical and aggressive surgery that presents a great challenge to the thoracic anesthesiologist. This surgery is performed routinely…
Read MoreLaboratory and clinical basis for hyperthermia as a component of intracavitary chemotherapy
International Journal of Hyperthermia. Volume 23, Issue 5 2007 , pages 431 – 442 [Link] Sugarbaker PH. Washington Cancer Institute, Washington, DC 20010, USA. paul.sugarbaker@medstar.net Abstract Intraoperative chemotherapy with heat has been identified as a treatment option for patients with cancer spread to peritoneal surfaces. This treatment modality is viewed as a supplement to several…
Read MoreLimited cardiotoxicity after extensive thoracic surgery and intraoperative hyperthermic intrathoracic chemotherapy with doxorubicin and cisplatin
Annals of Surgical Oncology. 2007 Oct;14(10):3019-26. Epub 2007 Jul 20. [Link] Eelco de Bree1, Serge van Ruth1, Carl E. Schotborgh2, Paul Baas3 and Frans A. N. Zoetmulder1 (1) Department of Surgical Oncology, Antoni van Leeuwenhoek Hospital/The Netherlands Cancer Institute, Amsterdam, The Netherlands (2)Department of Cardiology, Slotervaart Hospital, Amsterdam, The Netherlands (3) Department of Thoracic Oncology,…
Read MoreLocal recurrence model of malignant pleural mesothelioma for investigation of intrapleural treatment
European Journal of Cardio-Thoracic Surgery . 2007 May;31(5):773-8. Epub 2007 Mar 12. [Link] Opitz I, Lardinois D, Arni S, Hillinger S, Vogt P, Odermatt B, Rousson V, Weder W. Division of Thoracic Surgery, University Hospital Zurich, Zurich, Switzerland. Abstract Objective: Local recurrence remains a major problem in the treatment of malignant pleural mesothelioma. The aim…
Read MoreDiffuse malignant pleural mesothelioma
Kyobu Geka. 2007 Jan;60(1):35-9. [Link] Katsuragi N, Shiraishi Y, Kita H, Toishi M, Miyasaka Y, Tanaka S. Section of Chest Surgery, Fukujuji Hospital, Kiyose, Japan. Abstract Malignant pleural mesothelioma is an uncommon neoplasm that caused 647 deaths in Japan in 2004. The incidence of the disease is increasing and is estimated to reach its peak…
Read MoreA phase II study of intrapleural immuno-chemotherapy, pleurectomy/decortication, radiotherapy, systemic chemotherapy and long-term sub-cutaneous IL-2 in stage II-III malignant pleural mesothelioma
European Journal of Cardiothoracic Surgery. 2007 Mar;31(3):529-34. Epub 2006 Dec 26. [Link] Lucchi M, Chella A, Melfi F, Dini P, Ambrogi M, Fino L, Fontanini G, Mussi A. Division of Thoracic Surgery, Cardiac and Thoracic Department, University of Pisa, Pisa, Italy. Abstract Objective: From therapeutic nihilism to extremely aggressive management, there is a wide range…
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