Thrombocytopenia as an Immune-Related Adverse Event in Malignant Pleural Mesothelioma: A Case Report

JTO Clinical and Research Reports 2022 June 9 [Link] Takaaki Tanaka, Shoji Asakura, Kazuya Hisamatsu, Nobukazu Fujimoto Abstract A 69-year-old man presented with a pulmonary opacity at a regular medical check-up. He had been exposed to asbestos in a chemical fiber manufacturing setting. Result of positron emission tomography with computed tomography (CT) revealed fluorodeoxyglucose accumulations…

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Primary malignant pericardial mesothelioma with a survival of 2.5 years: a case report

Translational Cancer Research 2022 May [Link] Yan Yan, Wenli Lv, Yinghao Luo, Jianlin Hu, Jie Yang Abstract Background: Primary malignant pericardial mesothelioma (PMPM) is a highly malignant tumor originating in the pericardium serosum with clinical manifestations presenting as constrictive pericarditis, with pericardial tamponade and heart failure. Malignant pericardial mesothelioma is rare and has a poor…

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Histology of the pleural rind at [ 18 F]FDG PET/CT hot and cold spots in mesothelioma patients after talc pleurodesis and neoadjuvant chemotherapy

Pathology, Research and Practice 2021 December [Link] Alex Soltermann, Isabelle Opitz, Irene A Burger Abstract The role of 2-deoxy-2-[18F]fluoro-D-glucose positron emission tomography/computed tomography ([18F]FDG PET/CT) in evaluating induction chemotherapy in pleural mesothelioma (PM) patients is debated. We compared histology at tumor sites with high versus low [18F]FDG uptake in order to define a morphologic correlate…

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When cardiac surgery comes to its limits: a case report of pericardial mesothelioma invading the myocardium

European Heart Journal Case Reports 2021 July 7 [Link] Leo Pölzl, Jakob Hirsch, Agnes Mayr, Christian Uprimny, Georg Oberhuber, Hansjörg J Zwick, Ludwig Müller, Gerhard Pölzl Abstract Background: Primary pericardial mesothelioma (PPM) is a rare form of highly aggressive cancer. Many patients are diagnosed only at an advanced stage. Therefore, the overall survival rate is…

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Deep learning with deep convolutional neural network using FDG-PET/CT for malignant pleural mesothelioma diagnosis

Oncotarget 2021 June 18 [Link] Kazuhiro Kitajima, Hidetoshi Matsuo, Atsushi Kono, Kozo Kuribayashi, Takashi Kijima, Masaki Hashimoto, Seiki Hasegawa, Takamichi Murakami, Koichiro Yamakado Abstract Objectives: This study analyzed an artificial intelligence (AI) deep learning method with a three-dimensional deep convolutional neural network (3D DCNN) in regard to diagnostic accuracy to differentiate malignant pleural mesothelioma (MPM)…

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Response to Immune Checkpoint Inhibitor Therapy in Patients with Unresectable Recurrent Malignant Pleural Mesothelioma Shown by FDG-PET and CT

Cancers 2021 March 4 [Link] Kazuhiro Kitajima, Mitsunari Maruyama, Hiroyuki Yokoyama, Toshiyuki Minami, Takashi Yokoi, Akifumi Nakamura, Masaki Hashimoto, Nobuyuki Kondo, Kozo Kuribayashi, Takashi Kijima, Seiki Hasegawa, Koichiro Yamakado Abstract Background: To compare three FDG-PET criteria (EORTC, PERCIST, imPERCIST) with CT criteria (combined modified RECIST and RECIST 1.1) for response evaluation and prognosis prediction in…

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The prognostic value of 18F-fluorodeoxyglucose positron emission tomography/ computed tomography parameters in patients with malignant pleural mesothelioma

Turk Gogus Kalp Damar Cerrahisi Derg 2021 January 13 [Link] Bülent Mustafa Yenigün, Yusuf Kahya, Çiğdem Soydal, Nihal Ata Tutkun, Gökhan Kocaman, Emre Muhammed Koçak, Elgin Özkan, Serpil Dizbay Sak, Ayten Kayı Cangır Abstract Background: In this study, we aimed to investigate the prognostic value of metabolic 18F-fluorodeoxyglucose positron emission tomography/computed tomography parameters in malignant…

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Metastasis of Sarcomatoid Malignant Mesothelioma With p16/CDKN2A Deletion Manifested as a Subcutaneous Mass in the Back: A Case Report and Review of Literature

International Journal of Surgical Pathology 2021 March 17 [Link] Kai-Bo Chen, Ya-Jing Huang, Yi Huang, Zhi-Wei Wu, Xiao-Li Jin, Hang Zhang, Xue-Ping Xiang, Lin Chen, Li Chen Abstract Sarcomatoid malignant mesothelioma (MM) is a rare and aggressive disease, and its diagnosis is challenging. A 60-year-old man presented with a recurrent subcutaneous mass in his right…

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Diagnostic Laparoscopy Improves Staging of Malignant Pleural Mesothelioma with Routine PET Imaging

Annals of Thoracic Surgery 2020 December 1 [Link] R Taylor Ripley, Nihanth Palivela, Shawn S Groth, Eugene A Choi, Lorraine D Cornwell, Phillip W Carrott, George Van Buren, Taylor G Splawn, David J Sugarbaker, Bryan M Burt Abstract Background: With a multimodal treatment strategy, cytoreductive surgery extends survival in malignant pleural mesothelioma. Improving the accuracy…

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Widespread pulmonary invasion by malignant pleural mesothelioma: an important diagnostic consideration

Respirology Case Reports 2020 October 26 [Link] Mia MacMillan, Bapti Roy, Sally McLaren, Anna K Nowak, Rajesh Thomas, Y C Gary Lee Abstract We report a rare case of early and extensive pulmonary invasion of malignant pleural mesothelioma (MPM) in a 70-year-old woman. She first presented with a hydropneumothorax and subsequent workup, including video-assisted thoracoscopy…

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