Response to Immune Checkpoint Inhibitor Therapy in Patients with Unresectable Recurrent Malignant Pleural Mesothelioma Shown by FDG-PET and CT

Cancers 2021 March 4 [Link] Kazuhiro Kitajima, Mitsunari Maruyama, Hiroyuki Yokoyama, Toshiyuki Minami, Takashi Yokoi, Akifumi Nakamura, Masaki Hashimoto, Nobuyuki Kondo, Kozo Kuribayashi, Takashi Kijima, Seiki Hasegawa, Koichiro Yamakado Abstract Background: To compare three FDG-PET criteria (EORTC, PERCIST, imPERCIST) with CT criteria (combined modified RECIST and RECIST 1.1) for response evaluation and prognosis prediction in…

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The prognostic value of 18F-fluorodeoxyglucose positron emission tomography/ computed tomography parameters in patients with malignant pleural mesothelioma

Turk Gogus Kalp Damar Cerrahisi Derg 2021 January 13 [Link] Bülent Mustafa Yenigün, Yusuf Kahya, Çiğdem Soydal, Nihal Ata Tutkun, Gökhan Kocaman, Emre Muhammed Koçak, Elgin Özkan, Serpil Dizbay Sak, Ayten Kayı Cangır Abstract Background: In this study, we aimed to investigate the prognostic value of metabolic 18F-fluorodeoxyglucose positron emission tomography/computed tomography parameters in malignant…

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Metastasis of Sarcomatoid Malignant Mesothelioma With p16/CDKN2A Deletion Manifested as a Subcutaneous Mass in the Back: A Case Report and Review of Literature

International Journal of Surgical Pathology 2021 March 17 [Link] Kai-Bo Chen, Ya-Jing Huang, Yi Huang, Zhi-Wei Wu, Xiao-Li Jin, Hang Zhang, Xue-Ping Xiang, Lin Chen, Li Chen Abstract Sarcomatoid malignant mesothelioma (MM) is a rare and aggressive disease, and its diagnosis is challenging. A 60-year-old man presented with a recurrent subcutaneous mass in his right…

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Intussusception caused by small intestine metastasis of malignant pleural mesothelioma: a case report

Journal of Surgical Case Reports 2021 February 22 [Link] Michinori Hamaoka, Masataka Nakagawa, Hideki Nakahara, Rie Yamamoto, Takashi Nishisaka, Toshiyuki Itamoto Abstract Malignant pleural mesothelioma (MPM) is an aggressive form of malignant tumor that originates in the pleural mesothelioma and presents as a local disease in the affected hemithorax. Small intestine metastasis is a rare…

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Serum soluble mesothelin-related protein (SMRP) and fibulin-3 levels correlate with baseline malignant pleural mesothelioma (MPM) tumor volumes but are not useful as biomarkers of response in an immunotherapy trial

Lung Cancer 2021 January 14 [Link] Sharyn I Katz, Leonid Roshkovan, Ian Berger, Joseph S Friedberg, Evan W Alley, Charles B Simone 2nd, Andrew R Haas, Keith A Cengel, Daniel H Sterman, Steven M Albelda Abstract Objectives: Soluble mesothelin-related protein (SMRP) and fibulin-3 serum levels may serve as diagnostic and prognostic biomarkers of malignant pleural…

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Unusual radiologic presentations of malignant peritoneal mesothelioma

World Journal of Radiology 2020 December 28 [Link] Paul Hendrick Sugarbaker, James S Jelinek Abstract Background: Malignant peritoneal mesothelioma is an unusual disease process characterized radiologically by ascites and infiltration of the peritoneum by multiple small tumor nodules. Both parietal and visceral peritoneum are involved by the multiple malignant tumor nodules. Computed tomography (CT) has…

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Malignant pleural neoplasm with both differentiation of epithelioid mesothelioma and squamous-cell carcinoma, a rare phenomena

Diagnostic Cytopathology 2020 December 21 [Link] Ashley Re, David Shersher, Ashleigh Allen, Roland Schwarting, Shuyue Ren Abstract Malignant mesothelioma, a neoplasm arising within the serosal surfaces, has been linked closely to asbestos exposure. We present a case of 72-year-old male with a 27 year work-related history of asbestos exposure who presented with dyspnea. Chest computed…

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Delayed-Phase Enhancement for Evaluation of Malignant Pleural Mesothelioma on Computed Tomography: A Prospective Cohort Study

Clinical Lung Cancer 2020 June 14 [Link] Akash Patel, Leonid Roshkovan, Sally McNulty, Evan Alley, Drew A Torigian, Arun C Nachiappan, Maya Galperin-Aizenberg, Eduardo M Barbosa Jr, Joseph DiRienzi, Ian Berger, Urooj Khalid, Andrew R Haas, Sunil Singhal, E Paul Wileyto, Keith A Cengel, Sharyn I Katz Abstract Background: Radiologic assessment of malignant pleural mesothelioma…

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Secondary Renal Amyloidosis Associated With Asbestos-Related Pleuropulmonary Diseases

CEN Case Reports 2020 June 13 [Link] Ryoko Shibata, Tomomi Ozaki, Kazuhiro Tada, Takashi Aoyama, Maho Watanabe, Naoko Himuro, Koji Takahashi, Kenji Ito, Tetsuhiko Yasuno, Katsuhisa Miyake, Kosuke Masutani, Noriko Uesugi, Kazuki Nabeshima, Hitoshi Nakashima Abstract Here, we present a 67-year-old Japanese man who developed insidious-onset nephrotic syndrome. He had a history of occupational asbestos…

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Cisplatin Plus Pemetrexed Therapy and Subsequent Immune Checkpoint Inhibitor Administration for Malignant Peritoneal Mesothelioma Without Pleural Lesions: Case Report

Medicine 2020 May 29 [Link] Hiroaki Ikushima, Toshio Sakatani, Sayaka Ohara, Hideyuki Takeshima, Hajime Horiuchi, Teppei Morikawa, Kazuhiro Usui Abstract Rationale: Malignant peritoneal mesothelioma is a rare tumor with a poor prognosis and has no recommended therapy after first-line pemetrexed and platinum-based chemotherapy. Moreover, effects of immune checkpoint inhibitors on peritoneal mesothelioma remains to be…

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