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Mesothelioma-Line

Curated Journal Articles on Mesothelioma

Category Archives: Pleural

Malignant pleural mesothelioma; mesothelioma of the lining of the lungs, or pleura.

Dosimetric Correlates of Pulmonary Toxicity in Patients with Malignant Pleural Mesothelioma Receiving Radiation Therapy to the Intact Lungs.

Practical Radiation Oncology 2019 January 14 [Link] Thompson MR1, Dumane VA1, Lazarev SA1, Zia Y2, Rosenzweig KE3 INTRODUCTION: We aimed to determine dose-volume constraints that correlate with severe (grade ≥3) radiation pneumonitis (RP) in patients diagnosed with malignant pleural mesothelioma (MPM), treated using volumetric modulated arc therapy (VMAT). METHODS: Data from 40 patients with MPM who underwent pleurectomy decortication (P/D) and […]

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Molecular pathways and diagnosis in malignant mesothelioma: A review of the 14th International Conference of the International Mesothelioma Interest Group.

Lung Cancer 2019 January [Link] Chapel DB, Churg A, Santoni-Rugiu , Tsujimura T4, Hiroshima K5, Husain AN Abstract The pathologist plays a central role in the diagnosis and management of malignant mesothelioma, including definitive tissue-based diagnosis in conjunction with clinical and radiographic data; diverse ancillary studies of diagnostic, prognostic, and predictive importance; and research efforts to better define the pathobiology of […]

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Computational prediction of diagnosis and feature selection on mesothelioma patient health records.

PLos One 2019 January 10 [Link] Chicco D , Rovelli C BACKGROUND: Mesothelioma is a lung cancer that kills thousands of people worldwide annually, especially those with exposure to asbestos. Diagnosis of mesothelioma in patients often requires time-consuming imaging techniques and biopsies. Machine learning can provide for a more effective, cheaper, and faster patient diagnosis and feature […]

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MicroRNAs for the Diagnosis and Management of Malignant Pleural Mesothelioma: A Literature Review.

Frontiers in Oncology 2018 December 21 [Link] Lo Russo G, Tessari A, Capece M, Galli G, de Braud F, Garassino MC, Palmieri D Abstract Malignant pleural mesothelioma (MPM) is a rare and aggressive tumor with a variable incidence among different countries. Occupational asbestos exposure is the most important etiological factor and a very long latency […]

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Correlation of patient survival with clinical tumor measurements in malignant pleural mesothelioma.

European Radiology 2019 January 7 [Link] Li F, Ahmad M, Qayyum F, Straus CM, MacMahon H, Kindler H, Armato SG Abstract OBJECTIVES: To evaluate differences in the tumor response classifications that result from clinical measurements and to compare these response classifications with overall survival for patients with malignant pleural mesothelioma (MPM). METHODS: One hundred thirty-one […]

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Factors influencing malignant mesothelioma survival: a retrospective review of the National Mesothelioma Virtual Bank cohort.

F1000Research 2018 August 3 [Link] Amin W, Linkov F, Landsittel DP, Silverstein JC, Becich MJ Abstract Background: Malignant mesothelioma (MM) is a rare but deadly malignancy with about 3,000 new cases being diagnosed each year in the US. Very few studies have been performed to analyze factors associated with mesothelioma survival, especially for peritoneal presentation. […]

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Malignant mesothelioma: A histomorphological and immunohistochemical study of 24 cases from a tertiary care hospital in Southern India.

Indian Journal of Cancer 2018 April-June [Link] Hui M, Uppin SG, Bhaskar K, Kumar NN, Paramjyothi GK Abstract BACKGROUND: Malignant mesotheliomas are histologically heterogeneous neoplasms. Definite diagnosis requires a varied panel of immunohistochemical (IHC) markers to differentiate these from histological mimics. Only a few case series have been reported in the Indian literature where mesotheliomas […]

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Immunotherapy strategies for mesothelioma – the role of tumor specific neoantigens in a new era of precision medicine.

Expert Review of Respiratory Medicine 2018 December 30 [Link] Ye L, Ma S, Robinson BW, Creaney J Abstract Immunotherapy has long been considered a potential therapy for malignant mesothelioma and is currently being pursued as such. Some of the early phase clinical trials involving immunomodulators have demonstrated encouraging results and numerous clinical trials are underway […]

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The effect of rapid infusion of cisplatin on nephrotoxicity in patients with lung carcinoma.

Journal of Clinical Pharmacy and Therapeutics 2018 December 2018 [Link] Mense ES, Smit AAJ, Crul M, Franssen EJF Abstract WHAT IS KNOWN AND OBJECTIVE: The use of cisplatin in the treatment of lung carcinoma is limited by nephrotoxicity. The aim of this study was to determine whether the incidence of nephrotoxicity in patients with lung […]

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Pleural thickness after neoadjuvant chemotherapy is a prognostic factor in malignant pleural mesothelioma.

Journal of Thoracic and Cardiovascular Surgery 2019 January [Link] Hashimoto M, Takeuchi J, Takuwa T, Kuroda A, Nakamura A, Nakamichi T, Matsumoto S, Kondo N, Nakano T, Morimoto T, Hasegawa S Abstract OBJECTIVES: Definitive diagnosis of the T-component is sometimes challenging in malignant pleural mesothelioma (MPM). Pleural thickness has been reported to be a prognostic […]

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