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Mesothelioma-Line

Curated Journal Articles on Mesothelioma

Category Archives: Pleural

Malignant pleural mesothelioma; mesothelioma of the lining of the lungs, or pleura.

Mesothelin promotes epithelial-to-mesenchymal transition and tumorigenicity of human lung cancer and mesothelioma cells

Molecular Cancer 2017 March [a href=”https://www.ncbi.nlm.nih.gov/pubmed/28288645″>Link] He X, Wang L, Riedel H, Wang K, Yang Y, Dinu CZ, Rojanasakul Y Abstract BACKGROUND: Lung cancer and pleural mesothelioma are two of the most deadly forms of cancer. The prognosis of lung cancer and mesothelioma is extremely poor due to limited treatment modalities and lack of understanding […]

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Clinical safety and activity of pembrolizumab in patients with malignant pleural mesothelioma (KEYNOTE-028): preliminary results from a non-randomised, open-label, phase 1b trial

The Lancelot: Oncology 2017 March [Epub ahead of print] [Link] Alley EW, Lopez J, Santoro A, Morosky A, Saraf S, Piperdi B, van Brummelen E Abstract BACKGROUND: Malignant pleural mesothelioma is a highly aggressive cancer with poor prognosis and few treatment options following progression on platinum-containing chemotherapy. We assessed the safety and efficacy of pembrolizumab […]

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Physical function and health-related quality of life in patients undergoing surgical treatment for malignant pleural mesothelioma

Multinational Association of Supportive Care in Cancer 2017 March [Epub ahead of print] [Link] Tanaka T, Morishita S, Hashimoto M, Itani Y, Mabuchi S, Kodama N, Hasegawa S, Domen K Abstract Malignant pleural mesothelioma (MPM) is a rare cancer that affects the thin cell wall lining of internal organs and structures. Studies have shown that […]

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A pilot study of volumetric-modulated arc therapy for malignant pleural mesothelioma

Journal of Applied Clinical Medical Physics 2016 March [Link] Runxiao L1, Yankun C1, Lan W Abstract Malignant pleural mesothelioma (MPM) is an extremely difficult disease to treat. This pilot study investigates the feasibility of using volumetric-modulated arc therapy (VMAT) for malignant pleural mesothelioma (MPM), and compares VMAT to static field intensity-modulated radiotherapy (IMRT) for five […]

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Impact of tumour thickness on survival after radical radiation and surgery in malignant pleural mesothelioma

The European Respiratory Journal 2017 March 15 [Print 2017] [Link] de Perrot M, Dong Z, Bradbury P, Patsios D, Keshavjee S, Leighl NB, Hope A, Feld R, Cho J Abstract Tumour thickness was assessed to determine if this parameter could refine patients’ selection for multimodality therapy in malignant pleural mesothelioma.We reviewed 65 consecutive treatment-na├»ve malignant […]

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Mesothelioid reaction following talc pleurodesis: a case report.

General Thoracic and Cardiovascular Surgery 2017 March [Epub ahead of print] [Link] Faynberg T, Patel N, Nayar AP, Shienbaum AJ Abstract INTRODUCTION: Talc pleurodesis is a well-established procedure performed to obliterate the pleural space to prevent recurrent pleural effusion and/or recurrent pneumothorax. Pleurodesis is commonly accomplished by draining the pleural fluid, if present, followed by […]

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Amount of Epithelioid Differentiation Is a Predictor of Survival in Malignant Pleural Mesothelioma

The Annals of Thoracic Surgery 2017 March [Epub 2016 October] [Link] Vigneswaran WT, Kircheva DY, Ananthanarayanan V, Watson S, Arif Q, Celauro AD, Kindler HL, Husain AN Abstract BACKGROUND: Macroscopic complete surgical resection with adjuvant chemotherapy can provide a survival advantage in patients with malignant pleural mesothelioma (MPM). Patients with nonepithelioid histology are largely excluded […]

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Extended Pleurectomy-Decortication-Based Treatment for Advanced Stage Epithelial Mesothelioma Yielding a Median Survival of Nearly Three Years

The Annals of Thoracic Surgery 2017 March [Epub November 5] [Link] Friedberg JS, Simone CB 2nd, Culligan MJ, Barsky AR, Doucette A, McNulty S, Hahn SM, Alley E, Sterman DH, Glatstein E, Cengel KA Abstract BACKGROUND: The purpose of this study was to assess survival for patients with malignant pleural mesothelioma (MPM), epithelial subtype, utilizing […]

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Aberrant Cytokeratin 20 Reactivity in Epithelioid Malignant Mesothelioma: A Case Report

Applied Immunohistochemistry and Molecular Morphology 2017 February [Epub ahead of print] [Link] Manur R, Lamzabi I Abstract Malignant mesothelioma is an uncommon neoplasm that should be distinguished from the more common pulmonary adenocarcinomas and other metastatic lesions. Although diagnosis is based on morphologic features, immunohistochemical stains such as Calretinin, WT-1, CK-5/6, D2-40, Ber-Ep4, and MOC-31 […]

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Radiation therapy for malignant pleural mesothelioma

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