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Curated Journal Articles on Mesothelioma

Category Archives: Pleural

Malignant pleural mesothelioma; mesothelioma of the lining of the lungs, or pleura.

Mesothelioma continues to increase even 40 years after exposure – Evidence from long-term epidemiological observation

Lung Cancer (Amsterdam, Netherlands) 2017 June [Epub 2017 March 27] [Link] Świątkowska B, Szeszenia-Dąbrowska N Abstract BACKGROUND: Because asbestos dust is considered one of the most dangerous types of dust for people’s health, issues related to the effects of asbestos exposure still remain questions about the role of cessation of exposure. OBJECTIVES: The aim of […]

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Induction chemotherapy vs post-operative adjuvant therapy for malignant pleural mesothelioma

Expert review of respiratory medicine 2017 June [Epub ahead of print] [Link] Marulli G, Faccioli E, Bellini A, Mammana M, Rea F Abstract INTRODUCTION: Malignant pleural mesothelioma (MPM) is an aggressive neoplasia. Multidisciplinary treatments, including the association of induction and/or adjuvant therapeutic regimens with surgery, have been reported to give encouraging results. Current therapeutic options […]

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Biomarkers for early diagnosis of malignant mesothelioma: Do we need another moonshot?

Oncotarget 2017 May 17 [Epub ahead of print] [Link] Lagniau S, Lamote K, van Meerbeeck JP2, Vermaelen KY Abstract Early diagnosis of malignant pleural mesothelioma (MPM) is a challenge for clinicians. The disease is usually detected in an advanced stage which precludes curative treatment. We assume that only new and non-invasive biomarkers allowing earlier detection […]

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Deregulation of miRNAs in malignant pleural mesothelioma is associated with prognosis and suggests an alteration of cell metabolism

Scientific Reports 2017 June [

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Targeting CXCR4 with [68Ga]Pentixafor: a suitable theranostic approach in pleural mesothelioma?

Oncotarget 2017 May [Epub ahead of print] [Link] Lapa C, Kircher S, Schirbel A, Rosenwald A, Kropf S, Pelzer T, Walles T, Buck AK, Weber WA, Wester HJ, Herrmann K, Lückerath K Abstract C-X-C motif chemokine receptor 4 (CXCR4) is a key factor for tumor growth and metastasis in several types of human cancer. This […]

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Unusual Contiguous Soft Tissue Spread of Advanced Malignant Mesothelioma Detected by FDG PET/CT

Nuclear Medicine and Molecular Imaging 2017 June [Epub 2016 June] [Link] Zhang Y, Edwards J, Williams H, Hao Z, Khleif S, Pucar D Abstract Malignant pleural mesothelioma (MPM) is a tumor of mesodermal origin that arises from the serosa of the pleura, peritoneum, pericardium or tunica vaginalis. MPM is well known to have a poor […]

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Improved diagnosis and prognostication of patients with pleural malignant mesothelioma using biomarkers in pleural effusions and peripheral blood samples – a short report

Cell Oncology 2017 June 2 [Epub ahead of print] [Link] Beije N, Kraan J, den Bakker MA, Maat APWM, van der Leest C, Cornelissen R, Van NM, Martens JWM, Aerts JGJV, Sleijfer S Abstract PURPOSE: There is a lack of robust and clinically utilizable markers for the diagnosis and prognostication of malignant pleural mesothelioma (MPM). […]

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Whole exome sequencing of an asbestos-induced wild-type murine model of malignant mesothelioma

BMC Cancer 2017 June 2 [Link] Sneddon S, Patch AM, Dick IM, Kazakoff S, Pearson JV, Waddell N, Allcock RJN, Holt RA, Robinson BWS, Creaney J Abstract BACKGROUND: Malignant mesothelioma (MM) is an aggressive cancer of the pleural and peritoneal cavities caused by exposure to asbestos. Asbestos-induced mesotheliomas in wild-type mice have been used extensively […]

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Induction of IL-17 production from human peripheral blood CD4+ cells by asbestos exposure

International Journal of Oncology 2017 June [Epub May 9] [Link] Maeda M, Chen Y, Lee S, Kumagai-Takei N, Yoshitome K, Matsuzaki H, Yamamoto S, Hatayama T, Ikeda M, Nishimura Y, Otsuki T Abstract We have previously reported that chronic, recurrent and low-dose exposure to asbestos fibers causes a reduction in antitumor immunity. Investigation of natural […]

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Dose-time-response association between occupational asbestos exposure and pleural mesothelioma

Occupational and Environmental Medicine 2017 May [Epub ahead of print] [Link] Lacourt A, Lévêque E, Guichard E, Gilg Soit Ilg A, Sylvestre MP, Leffondré K Abstract OBJECTIVES: Early occupational exposure to asbestos has been shown to be associated with an increased risk of pleural mesothelioma (PM), which suggests that the timing of exposure might play […]

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