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Curated Journal Articles on Mesothelioma

Category Archives: Pleural

Malignant pleural mesothelioma; mesothelioma of the lining of the lungs, or pleura.

Epithelioid Malignant Mesothelioma Metastatic to the Skin: A Case Report and Review of the Literature

Journal of Cutaneous Pathology 2017 August [Epub ahead of print] [Link] Ward RE, Ali SA, Kuhar M Abstract Mesothelioma is a rare form of cancer arising from a monolayer of mesothelial cells that form the lining of the internal body cavities and organs, with the vast majority of cases arising from the pleura (65-80%), less […]

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Malignant Pleural Mesothelioma: State of the art and advanced cell therapy

European Journal of Medicinal Chemistry 2017 August [Epub ahead of print] [Link] Facchetti G, Petrella F, Spaggiari L, Rimoldi I Abstract Malignant Pleural Mesothelioma (MPM) is an aggressive malignancy highly resistant to chemotherapy, with a response rate of 20% of patients and for this reason an efficient treatment is still a challenge. Platinum-based chemotherapy in […]

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Isolated thoracic perfusion with chemofiltration for progressive malignant pleural mesothelioma

OncoTargets and Therapy 2017 June [Link] Aigner KR, Selak E, Gailhofer S Abstract INTRODUCTION: Therapy of malignant pleural mesothelioma and especially the adequate role of surgery in this context remain the subject of controversial discussions. Radical surgery in particular, which is associated with substantial morbidity, failed to translate into a definite survival advantage. We report […]

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Malignant pleural mesothelioma segmentation for photodynamic therapy planning

Computerized Medical Imaging Society 2017 July [Epub ahead of print] [Link] Brahim W, Mestiri M, Betrouni N, Hamrouni K Abstract Medical imaging modalities such as computed tomography (CT) combined with computer-aided diagnostic processing have already become important part of clinical routine specially for pleural diseases. The segmentation of the thoracic cavity represents an extremely important […]

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Italian pool of asbestos workers cohorts: mortality trends of asbestos-related neoplasms after long time since first exposure

Occupational and Environmental Medicine 2017 August [Epub ahead of print] [Link] Ferrante D, et.al. Abstract OBJECTIVE: Asbestos is a known human carcinogen, with evidence for malignant mesothelioma (MM), cancers of lung, ovary, larynx and possibly other organs. MM rates are predicted to increase with a power of time since first exposure (TSFE), but the possible […]

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The differential diagnosis between pleural sarcomatoid mesothelioma and spindle cell/pleomorphic (sarcomatoid) carcinomas of the lung: Evidence-Based guidelines from the International Mesothelioma Panel and the MESOPATH National Reference Center.

Human Pathology 2017 August 4 [Epub ahead of print] [Link] Marchevsky AM, et. al. Abstract Immunohistochemistry is used to distinguish sarcomatoid malignant mesotheliomas (SMM) from spindle cell and pleomorphic carcinomas (SPC) but there are no guidelines on how to interpret cases that show overlapping or equivocal immunohistochemical findings. A systematic literature review of the immunophenotype […]

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Functional image guided radiation therapy planning in volumetric modulated arc therapy for patients with malignant pleural mesothelioma

Advances in Radiation Oncology [2017 February] [Link] Doi Y, Kimura T, Nakashima T, Takeuchi Y, Takahashi I, Nishibuchi I, Murakami Y, Nagata Y Abstract PURPOSE: To investigate the incorporation of functional lung image-derived low-attenuation area (LAA) based on 4-dimensional computed tomography (4D-CT) in volumetric modulated arc therapy (VMAT) planning for patients with malignant pleural mesothelioma […]

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Diagnostic application of BAP1 immunohistochemistry to differentiate pleural mesothelioma from metastatic pleural tumors

Histopathology 2017 July 26 [Epub ahead of print] [Link] Yoshimura M, Kinoshita Y, Hamasaki M, Matsumoto S, Hida T, Oda Y, Nabeshima K Abstract Malignant pleural mesothelioma (MPM) is the most common primary pleural tumor and an aggressive neoplasm that arises from mesothelium of the pleura. The prognosis is poor with the overall median survival […]

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Intraoperative adjuncts for malignant pleural mesothelioma

Translational Lung Cancer Research 2017 June [Link] Chan WH, Sugarbaker DJ, Burt BM Abstract Malignant pleural mesothelioma (MPM) is a rapidly fatal disease. Multimodality surgically based therapies may extend survival in select patients, however, local relapse after resection is common. Novel intraoperative adjunctive therapies including heated intraoperative chemotherapy (HIOC), heated intraoperative povidone-iodine (PVP-I), and photodynamic […]

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Tremelimumab as second-line or third-line treatment in relapsed malignant mesothelioma (DETERMINE): a multicentre, international, randomised, double-blind, placebo-controlled phase 2b trial

The Lancet.Oncology 2017 July 17 [Epub ahead of print] [Link] Maio M, Scherpereel A, Calabr├▓ L, Aerts J, Perez SC, Bearz A, Nackaerts K, Fennell DA, Kowalski D, Tsao AS, Taylor P, Grosso F, Antonia SJ, Nowak AK, Taboada M, Puglisi M, Stockman PK, Kindler HL Abstract BACKGROUND: New therapeutic strategies for malignant mesothelioma are […]

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