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Mesothelioma-Line

Curated Journal Articles on Mesothelioma

Category Archives: Pleural

Malignant pleural mesothelioma; mesothelioma of the lining of the lungs, or pleura.

Matrix Metalloproteinases Polymorphisms as Baseline Risk Predictors in Malignant Pleural Mesothelioma.

Radiology and Oncology 2018 February 7 [Link] Strbac D, Goricar K, Dolzan V, Kovac V Abstract BACKGROUND: Malignant mesothelioma (MM) is a rare disease, linked to asbestos exposure in more than 80% of the cases. Matrix metalloproteinases (MMPs) have been identified as modulators of the tumour microenvironment and carcinogenesis. Polymorphisms of selected MMPs have been […]

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Biomarkers for Predicting Malignant Pleural Mesothelioma in a Mexican Population.

International Journal of Medical Sciences 2018 June 4 [Link] Aguilar-Madrid G, Pesch B, Calderón-Aranda ES, Burek K, Jiménez-Ramírez C, Juárez-Pérez CA, Ochoa-Vázquez MD, Torre-Bouscoulet L, Acosta-Saavedra LC, Sada-Ovalle I, García-Figueroa J, Alvarado-Cabrero I, Castillo-González P, Báez-Saldaña AR, Pérez-Padilla JR, Osnaya-Juárez J, Rivera-Rosales RM, García-Bazán EM, Bautista-Aragón YL, Lazcano-Hernandez E, Munguía-Canales DA, Argote-Greene LM, Taeger D, […]

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The characteristics of asbestos-related disease claims made to the Korea Workers’ Compensation and Welfare Service (KCOMWEL) from 2011 to 2015.

Annals of Occupational and Environmental Medicine 2018 July 11 [Link] An YS, Kim HD, Kim HC, Jeong KS, Ahn YS Abstract BACKGROUND: This study aimed to enhance understanding of the epidemiologic characteristics of asbestos-related diseases, and to provide information that could inform policy-making aimed at prevention and compensation for occupational asbestos exposure, through analyzing asbestos-related […]

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Epidemiological surveillance of mesothelioma mortality in Italy.

Cancer Epidemiology 2018 July 7 [Link] Fazzo L, Minelli G, De Santis M, Bruno C, Zona A, Conti S, Comba P Abstract BACKGROUND: Malignant mesothelioma (MM) is causally linked to asbestos exposure with an estimated etiological fraction of 80% or more. METHODS: Standardized rates of all mesothelioma (C45, ICD-10) and malignant pleural mesothelioma (C45.0, ICD-10) […]

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Adenosine diphosphate regulates MMP2 and MMP9 activity in malignant mesothelioma cells.

Annals of the New York Academy of Sciences 2018 July 8 [Link] Muscella A, Cossa LG, Vetrugno C, Antonaci G, Marsigliante S Abstract Although an association between cancer progression and matrix metalloproteinase (MMP) 2 and MPP9 expression has been known, the expression, nuclear localization, and physiologically controlled activation of these two MMPs have not been […]

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Chemo-manipulation of tumor blood vessels by a metal-based anticancer complex enhances antitumor therapy.

Scientific Reports 2018 July 6 [Link] Riedel T, Cavin S, van den Bergh H, Krueger T, Liaudet L, Ris HB, Dyson PJ, Perentes JY Abstract Human pleural mesothelioma is an incurable and chemoresistant cancer. Using a nude mouse xenograft model of human pleural mesothelioma, we show that RAPTA-T, a compound undergoing preclinical evaluation, enhances tumor […]

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Dynamic contrast-enhanced CT for the assessment of tumour response in malignant pleural mesothelioma: a pilot study.

European Radiology 2018 July 2 [Link] Gudmundsson E, Labby Z, Straus CM, Sensakovic WF, Li F, Rose B, Cunliffe A, Kindler HL, Armato SG Abstract OBJECTIVES: The aim of this pilot study was to investigate the utility of haemodynamic parameters derived from dynamic contrast-enhanced computed tomography (DCE-CT) scans in the assessment of tumour response to […]

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Pirfenidone decreases mesothelioma cell proliferation and migration via inhibition of ERK and AKT and regulates mesothelioma tumor microenvironment in vivo.

Scientific Reports 2018 July 3 [Link] Li C, Rezov V, Joensuu E, Vartiainen V, Rönty M, Yin M, Myllärniemi M, Koli K Abstract Malignant mesothelioma is an aggressive cancer with poor prognosis. It is characterized by prominent extracellular matrix, mesenchymal tumor cell phenotypes and chemoresistance. In this study, the ability of pirfenidone to alter mesothelioma […]

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5T4 is associated with favorable outcome for mesothelioma and a target for antibody drug conjugates.

Journal of Thoracic Oncology 2018 June 26 [Link] Schunselaar LM, Monkhorst K, van der Noort V, Wijdeven R, Peters D, Zwart W, Neefjes J, Baas P Abstract OBJECTIVES: The prognosis for patients with mesothelioma is poor, which urges the need for the development of better treatment options. Antibody drug conjugates (ADCs) are gaining interest as […]

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The asbestos-carbon nanotube analogy: An update.

Toxicology and Applied Pharmacology 2018 June 27 [Link] Kane AB, Hurt RH, Gao H Abstract Nanotechnology is an emerging industry based on commercialization of materials with one or more dimensions of 100 nm or less. Engineered nanomaterials are currently incorporated into thin films, porous materials, liquid suspensions, or filler/matrix nanocomposites with future applications predicted in energy […]

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