MesotheliomaCenter's

Mesothelioma-Line

Curated Journal Articles on Mesothelioma

Category Archives: Epithelioid

Epitheliod mesothelioma makes up between 50% and 70% of all diagnosed cases of mesothelioma; it also tends to have the best prognosis.

Pleurectomy-decortication in malignant pleural mesothelioma: are different surgical techniques associated with different outcomes? Results from a multicentre study

European Journal of Cardio-Throacic Surgery 2017 April [Epub ahead of print] [Link] Marulli G, Breda C, Fontana P, Ratto GB, Leoncini G, Alloisio M, Infante M, Luzzi L, Paladini P, Oliaro A, Ruffini E, Benvenuti MR, Pariscenti G, Spaggiari L, Casiraghi M, Rusca M, Carbognani P, Ampollini L, Facciolo F, Leuzzi G, Mucilli F, Camplese […]

Comments Off on Pleurectomy-decortication in malignant pleural mesothelioma: are different surgical techniques associated with different outcomes? Results from a multicentre study

Malignant pleural mesothelioma: single-institution experience of 101 patients over a 15-year period.

Acta Chirugica Belgica 2017 June [Link] Domen A, De Laet C, Vanderbruggen W, Gielis J, Hendriks JM, Lauwers P, Janssens A, Hiddinga B, Van Meerbeeck JP, Van Schil PE Abstract BACKGROUND: Malignant pleural mesothelioma (MPM) is a rare but aggressive neoplasm that typically originates from the mesothelial surfaces of the pleural cavity. Exposure to asbestos […]

Comments Off on Malignant pleural mesothelioma: single-institution experience of 101 patients over a 15-year period.

Histopathologic features predict survival in diffuse pleural malignant mesothelioma on pleural biopsies

International Journal of Pathology 2017 March 27 [Epub ahead of print] [Link] Habougit C, Trombert-Paviot B, Karpathiou G, Casteillo F, Bayle-Bleuez S, Fournel P, Vergnon JM, Tiffet O, Péoc’h M, Forest F Abstract Malignant pleural mesothelioma is a rare tumor with a poor prognosis. The only universally recognized pathological prognostic factor is histopathological subtype with […]

Comments Off on Histopathologic features predict survival in diffuse pleural malignant mesothelioma on pleural biopsies

Improved Outcomes with Modern Lung-Sparing Trimodality Therapy in Patients with Malignant Pleural Mesothelioma.

Journal of Thoracic Oncology 2017 March [Epub ahead of print] [Link] Shaikh F, Zauderer MG, von Reibnitz D, Wu AJ, Yorke ED, Foster A, Shi W, Zhang Z, Adusumilli PS, Rosenzweig KE, Krug LM, Rusch VW, Rimner A Abstract INTRODUCTION: Higher target conformity and better sparing of organs at risk with modern radiotherapy (RT) may […]

Comments Off on Improved Outcomes with Modern Lung-Sparing Trimodality Therapy in Patients with Malignant Pleural Mesothelioma.

Mesothelin promotes epithelial-to-mesenchymal transition and tumorigenicity of human lung cancer and mesothelioma cells

Molecular Cancer 2017 March [a href=”https://www.ncbi.nlm.nih.gov/pubmed/28288645″>Link] He X, Wang L, Riedel H, Wang K, Yang Y, Dinu CZ, Rojanasakul Y Abstract BACKGROUND: Lung cancer and pleural mesothelioma are two of the most deadly forms of cancer. The prognosis of lung cancer and mesothelioma is extremely poor due to limited treatment modalities and lack of understanding […]

Comments Off on Mesothelin promotes epithelial-to-mesenchymal transition and tumorigenicity of human lung cancer and mesothelioma cells

Is less also better? A single-institution experience on treatment of early stage Malignant Pleural Mesothelioma.

European Journal of Surgical Oncology 2017 February [Epub ahead of print] [Link] Bertoglio P1, Ambrogi MC, Chella A, Aprile V, Dini P, Korasidis S, Fanucchi O, Mussi A Abstract OBJECTIVES: No clear evidence of which surgical procedure should be performed for early stage mesothelioma is available to date. We analyzed our 10-year experience in the […]

Comments Off on Is less also better? A single-institution experience on treatment of early stage Malignant Pleural Mesothelioma.

Amount of Epithelioid Differentiation Is a Predictor of Survival in Malignant Pleural Mesothelioma

The Annals of Thoracic Surgery 2017 March [Epub 2016 October] [Link] Vigneswaran WT, Kircheva DY, Ananthanarayanan V, Watson S, Arif Q, Celauro AD, Kindler HL, Husain AN Abstract BACKGROUND: Macroscopic complete surgical resection with adjuvant chemotherapy can provide a survival advantage in patients with malignant pleural mesothelioma (MPM). Patients with nonepithelioid histology are largely excluded […]

Comments Off on Amount of Epithelioid Differentiation Is a Predictor of Survival in Malignant Pleural Mesothelioma

Extended Pleurectomy-Decortication-Based Treatment for Advanced Stage Epithelial Mesothelioma Yielding a Median Survival of Nearly Three Years

The Annals of Thoracic Surgery 2017 March [Epub November 5] [Link] Friedberg JS, Simone CB 2nd, Culligan MJ, Barsky AR, Doucette A, McNulty S, Hahn SM, Alley E, Sterman DH, Glatstein E, Cengel KA Abstract BACKGROUND: The purpose of this study was to assess survival for patients with malignant pleural mesothelioma (MPM), epithelial subtype, utilizing […]

Comments Off on Extended Pleurectomy-Decortication-Based Treatment for Advanced Stage Epithelial Mesothelioma Yielding a Median Survival of Nearly Three Years

Serum mesothelin, osteopontin and vimentin: useful markers for clinical monitoring of malignant pleural mesothelioma

International Journal of Biological Markers 2017 March [Link] Bonotti A, Simonini S, Pantani E, Giusti L, Donadio E, Mazzoni MR, Chella A, Marconi L, Ambrosino N, Lucchi M, Mussi A, Cristaudo A, Foddis R Abstract INTRODUCTION: Malignant pleural mesothelioma (MPM) is a relatively rare tumor, with the epithelioid type occurring more frequently. Several biomarkers have […]

Comments Off on Serum mesothelin, osteopontin and vimentin: useful markers for clinical monitoring of malignant pleural mesothelioma

The Immune Microenvironment, Genome -Wide Copy Number Aberrations and Survival in Mesothelioma

Journal of Thoracic Oncology 2017 February [Epub ahead of print] [Link] Thapa B, Salcedo A, Lin X, Walkiewicz M, Murone C, Ameratunga M, Asadi K, Deb S, Barnett SA, Knight S, Mitchell P, Watkins DN, Boutros PC, John T Abstract INTRODUCTION: Results of recent clinical studies of immune checkpoint inhibitors in malignant pleural mesothelioma (MPM) […]

Comments Off on The Immune Microenvironment, Genome -Wide Copy Number Aberrations and Survival in Mesothelioma