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Curated Journal Articles on Mesothelioma

Category Archives: Epithelioid

Epitheliod mesothelioma makes up between 50% and 70% of all diagnosed cases of mesothelioma; it also tends to have the best prognosis.

Kdm6a and Kdm6b: Altered expression in malignant pleural mesothelioma

International Journal of Oncology 2017 February 9 [Epub ahead of print] [Link] Cregan S, Breslin M, Roche G, Wennstedt S, MacDonagh L, Albadri C, Gao Y, O’Byrne KJ, Cuffe S, Finn SP, Gray SG Abstract Malignant pleural mesothelioma (MPM) is a rare aggressive cancer of the pleura primarily associated with prior exposure to asbestos. The […]

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Tissue transglutaminase (TG2) enables survival of human malignant pleural mesothelioma cells in hypoxia

Cell Death & Disease 2017 February [Link Zonca S, Pinton G, Wang Z, Soluri MF, Tavian D, Griffin M, Sblattero D, Moro L Abstract Malignant pleural mesothelioma (MPM) is an aggressive tumor linked to environmental/occupational exposure to asbestos, characterized by the presence of significant areas of hypoxia. In this study, we firstly explored the expression […]

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Blockage of epithelial to mesenchymal transition and upregulation of let 7b are critically involved in ursolic acid induced apoptosis in malignant mesothelioma cell

International Journal of Biological Sciences 2016 October [Link] Sohn EJ, Won G, Lee J, Yoon SW, Lee I, Kim HJ, Kim SH Abstract Malignant pleural mesothelioma (MPN), which is caused by asbestos exposure, is one of aggressive lung tumors. In the present study, we elucidated the anti-tumor mechanism of ursolic acid in malignant mesotheliomas. Ursolic […]

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Usefulness of p16/CDKN2A fluorescence in situ hybridization and BAP1 immunohistochemistry for the diagnosis of biphasic mesothelioma

Annals of diagnostic pathology 2017 Feb [Epub 2016 October 22] [Link] Wu D, Hiroshima K, Yusa T, Ozaki D, Koh E, Sekine Y, Matsumoto S, Nabeshima K, Sato A, Tsujimura T, Yamakawa H, Tada Y, Shimada H, Tagawa M Abstract Malignant mesothelioma is a highly aggressive neoplasm, and the histologic subtype is one of the […]

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Deciduoid mesothelioma of the thorax: A comprehensive review of the scientific literature

The Clinical Respiratory Journal 2016 December 27 [Epub ahead of print] [Link] Paliogiannis P, Putzu C, Ginesu GC, Cossu ML, Feo CF, Attene F, Scognamillo F1, Nonnis R1, Cossu A1, Palmieri G4, Pirina P5, Fois A Abstract OBJECTIVE: Deciduoid mesothelioma is a rare variant of malignant epithelioid mesothelioma. It often involves the peritoneum, but also […]

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The importance of EZH2 and MOC-31 expression in the differential diagnosis of benign and malignant effusions

Diagnostic Cytopathology 2016 December 26 [Epub ahead of print] [Link] Sadullahoglu C, Nart D, Veral A Abstract BACKGROUND: All malignant tumors may spread throughout the pleural, peritoneal, and pericardial cavities. The presence of tumor cells in serosal fluid is a poor prognostic indicator. It may be difficult to differentiate nuclear atypia of mesothelial cells due […]

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Metachronous Uterine Endometrioid Adenocarcinoma and Peritoneal Mesothelioma in Lynch Syndrome: A Case Report

International Journal of Surgical Pathology 2016 November [Epub ahead of print] [Link] Lu Y, Milchgrub S, Khatri G, Gopal P Abstract Lynch syndrome is a hereditary disease with germline mutation in a DNA mismatch repair gene, most often presenting with colorectal and/or endometrial carcinomas; however, the spectrum of Lynch syndrome-associated tumors is expanding. In this […]

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Chest wall resection for mesothelioma recurrence after surgery

Asian Cardiovascular & Thoracic Annals 2016 November [Epub 2016 October 9] [Link] Bertoglio P, Fanucchi O, Ricciardi S, Chella A, Lucchi M, Mussi A Abstract Malignant pleural mesothelioma is an aggressive and usually fatal disease, and its optimal management is still under debate. Surgery for recurrent malignant mesothelioma has been reported rarely in highly selected […]

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Diagnostic Utility of Pleural Fluid Cell Block versus Pleural Biopsy Collected by Flex-Rigid Pleuroscopy for Malignant Pleural Disease: A Single Center Retrospective Analysis

PLoS One 2016 November 23 [Link] Miyoshi S, Sasada S, Izumo T, Matsumoto Y, Tsuchida T Abstract BACKGROUND: Some trials recently demonstrated the benefit of targeted treatment for malignant disease; therefore, adequate tissues are needed to detect the targeted gene. Pleural biopsy using flex-rigid pleuroscopy and pleural effusion cell block analysis are both useful for […]

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Malignant pleural mesothelioma and mesothelial hyperplasia: A new molecular tool for the differential diagnosis

Oncotarget 2016 November 7 [Epub ahead of print] [Link] Bruno R, Alì G, Giannini R, Proietti A, Lucchi M, Chella A, Melfi F, Mussi A, Fontanini G Abstract Malignant pleural mesothelioma (MPM) is a rare asbestos related cancer, aggressive and unresponsive to therapies. Histological examination of pleural lesions is the gold standard of MPM diagnosis, […]

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