Diffuse mesothelioma
Splicing modulation as novel therapeutic strategy against diffuse malignant peritoneal mesothelioma.
EBioMedicine 2018 December 20 [Link] Sciarrillo R1, Wojtuszkiewicz A2, El Hassouni B, Funel N, Gandellini P, Lagerweij T, Buonamici S, Blijlevens M, Zeeuw van der Laan EA, Zaffaroni N, Deraco M, Kusamura S, Würdinger T, Peters GJ, Molthoff CFM, Jansen G, Kaspers GJL, Cloos J, Giovannetti E Abstract INTRODUCTION: Therapeutic options for diffuse malignant peritoneal…
Read MoreDiffuse peritoneal mesothelioma: A case series of 62 patients including paraoccupational exposures to chrysotile asbestos
American Journal of Industrial Medicine 2017 September [Epub ahead of print] [Link] Kradin RL1,2, Eng G2, Christiani DC Abstract BACKGROUND: Diffuse peritoneal malignant mesothelioma (DPM) is caused by exposure to asbestos. The medical literature has linked DPM primarily to high levels of asbestos exposure, in particular amosite. Controversy persists as to whether chrysotile is capable…
Read MoreExpression of ALCAM (CD166) and PD-L1 (CD274) independently predicts shorter survival in malignant pleural mesothelioma
Human Pathology 2017 August 12 [Epub ahead of print] [Link] Inaguma S, Lasota J, Wang Z, Czapiewski P, Langfort R, Rys J, Szpor J, Waloszczyk P, Okoń K, Biernat W, Ikeda H, Schrump DS, Hassan R, Miettinen M Abstract Diffuse malignant mesothelioma of the pleura is a highly aggressive tumor typically associated with short survival.…
Read MoreSignificant Clinical Benefit of Pemetrexed-based Chemotherapy for Advanced Diffuse Malignant Peritoneal Mesothelioma: A Case Presentation
Indian Journal of Medical and Paediatric Oncology 2017 January-March [Link] Peitl M, Seiwerth S, Bašić-Koretić M, Šantek F Abstract Diffuse malignant peritoneal mesothelioma (DMPM) is generally an understudied disease, largely because most molecular and clinical studies of mesothelioma have been conducted in patients with the more common malignant pleural mesothelioma. We present the case of…
Read MorePeritoneal Deciduoid Mesothelioma
International Journal of Surgical Pathology 2017 January [Epub ahead of print] [Link] Dominiak N, Graybill W, Gunning W, Richardson MS, Spruill LS Abstract This report highlights a diagnostically challenging case of diffuse deciduoid mesothelioma occurring in the peritoneum of a 25-year-old woman, 8 months postpartum. Optimally debulked tumor consisted of sheets of polygonal cells arranged…
Read MoreSmall bowel metastasis from pancreatic cancer in a long-term survival patient with synchronous advanced malignant pleural mesothelioma: A case report and literature review
Oncology Letters 2016 December [Epub 2016 October] [Link] Fasano M, Corte CM, Vicidomini G, Scotti V, Rambaldi PF, Fiorelli A, Accardo M, De Vita F, Santini M, Ciardiello F, Morgillo F Abstract Diffuse malignant pleural mesothelioma (MPM) is an aggressive tumor that originates from the surface of the pleura. Approximately 70% of cases are associated…
Read MoreA Histomorphologic Grading System That Predicts Overall Survival in Diffuse Malignant Peritoneal Mesothelioma With Epithelioid Subtype
The American Journal of Surgical Pathology 2016 July 19 [Epub ahead of print] [Link] Valente K, Blackham AU, Levine E, Russell G, Votanopoulos KI, Stewart JH, Shen P, Geisinger KR, Sirintrapun SJ Abstract Diffuse malignant peritoneal mesothelioma (MPeM) is rare and arises from peritoneal serosal surfaces. Although it shares similar histomorphology with its counterpart, malignant…
Read MoreThe Potential Protective Effects of Polyphenols in Asbestos-Mediated Inflammation and Carcinogenesis of Mesothelium.
Nutrients 2016 May 9 [Link] Benvenuto M, Mattera R, Taffera G, Giganti MG, Lido P, Masuelli L, Modesti A, Bei R. Abstract Malignant Mesothelioma (MM) is a tumor of the serous membranes linked to exposure to asbestos. A chronic inflammatory response orchestrated by mesothelial cells contributes to the development and progression of MM. The evidence…
Read MoreDiffuse malignant mesothelioma and synchronous lung cancer: A clinicopathological study of 18 cases.
Lung Cancer (Amsterdam, Netherlands) 2016 May 9 [Epub ahead of print] [Link] Butnor KJ, Brownlee NA, Mahar A, Pavlisko EN, Sporn TA, Roggli VL. Abstract OBJECTIVES: To examine the clinicopathologic characteristics of individuals with diffuse malignant mesothelioma (DMM) occurring concurrently with lung cancer (LC). MATERIALS AND METHODS: A database of approximately 3800 patients with DMM…
Read MoreDiffuse Malignant Peritoneal Mesothelioma Presenting with Psammomatous Calcification on a Cervical Smear
Acta Cytologica 2016 February 5 [Epub ahead of print] [Link] Tan A, Cohen P, Raoofi M, Tan J, Mesbah Ardakani N, Sterrett G. Abstract Background Psammoma bodies in cervical smears are rare but may be associated with benign and malignant diseases of the female genital tract. Case A 52-year-old nulliparous woman presented with a 2-month…
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