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Curated Journal Articles on Mesothelioma

Category Archives: Biphasic or Mixed

Combination of epithilioid and sarcomatoid mesothelioma types. Approximately 20-35% of cases are classified as mixed or biphasic mesothelioma.

Kdm6a and Kdm6b: Altered expression in malignant pleural mesothelioma

International Journal of Oncology 2017 February 9 [Epub ahead of print] [Link] Cregan S, Breslin M, Roche G, Wennstedt S, MacDonagh L, Albadri C, Gao Y, O’Byrne KJ, Cuffe S, Finn SP, Gray SG Abstract Malignant pleural mesothelioma (MPM) is a rare aggressive cancer of the pleura primarily associated with prior exposure to asbestos. The […]

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Tissue transglutaminase (TG2) enables survival of human malignant pleural mesothelioma cells in hypoxia

Cell Death & Disease 2017 February [Link Zonca S, Pinton G, Wang Z, Soluri MF, Tavian D, Griffin M, Sblattero D, Moro L Abstract Malignant pleural mesothelioma (MPM) is an aggressive tumor linked to environmental/occupational exposure to asbestos, characterized by the presence of significant areas of hypoxia. In this study, we firstly explored the expression […]

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Small bowel metastasis from pancreatic cancer in a long-term survival patient with synchronous advanced malignant pleural mesothelioma: A case report and literature review

Oncology Letters 2016 December [Epub 2016 October] [Link] Fasano M, Corte CM, Vicidomini G, Scotti V, Rambaldi PF, Fiorelli A, Accardo M, De Vita F, Santini M, Ciardiello F, Morgillo F Abstract Diffuse malignant pleural mesothelioma (MPM) is an aggressive tumor that originates from the surface of the pleura. Approximately 70% of cases are associated […]

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Usefulness of p16/CDKN2A fluorescence in situ hybridization and BAP1 immunohistochemistry for the diagnosis of biphasic mesothelioma

Annals of diagnostic pathology 2017 Feb [Epub 2016 October 22] [Link] Wu D, Hiroshima K, Yusa T, Ozaki D, Koh E, Sekine Y, Matsumoto S, Nabeshima K, Sato A, Tsujimura T, Yamakawa H, Tada Y, Shimada H, Tagawa M Abstract Malignant mesothelioma is a highly aggressive neoplasm, and the histologic subtype is one of the […]

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Polyanionic Biopolymers for the Delivery of Pt(II) Cationic Antiproliferative Complexes

Bioinorganic Chemistry and Applications [Epub 2016 September 28] [Link] Ravera M, Gabano E, Zanellato I, Perin E, Arrais A, Osella D Abstract Phenanthriplatin, that is, (SP-4-3)-diamminechlorido(phenanthridine)platinum(II) nitrate, an effective antitumor cationic Pt(II) complex, was loaded on negatively charged dextran sulfate (DS) as a model vector for drug delivery via electrostatic interactions. The free complex and […]

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Amount of Epithelioid Differentiation is a Predictor of Survival in Malignant Pleural Mesothelioma

The Annals of Thoracic Surgery 2016 October 17 [Epub ahead of print] [Link] Vigneswaran WT, Kircheva DY, Ananthanarayanan V, Watson S, Arif Q, Celauro AD, Kindler HL, Husain AN Abstract BACKGROUND: Macroscopic complete surgical resection with adjuvant chemotherapy can provide a survival advantage in patients with malignant pleural mesothelioma (MPM). Patients with nonepithelioid histology are […]

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Asbestos exposure and histological subtype of malignant mesothelioma

Occupational and Environmental Medicine 2016 November [Epub 2016 August 19] [Link] Franklin P, Alfonso H, Reid A, Olsen N, Shilkin KB, Brims F, de Klerk N, Musk AW Abstract BACKGROUND: Malignant mesothelioma (MM) has distinct histological subtypes (epithelioid, sarcomatoid and biphasic) with variable behaviour and prognoses. It is well recognised that survival time varies with […]

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Biphasic Malignant Pleural Mesothelioma Masquerading as a Primary Skeletal Tumor

Case Reports in Pulmonology [Epub 31 August] [Link] Gleason JB, Tashtoush B, Diacovo MJ Abstract Biphasic malignant pleural mesothelioma is a rare malignant tumor, usually presenting as a pleural-based mass in a patient with history of chronic asbestos exposure. We herein report a case of a 41-year-old man who presented with chest pain and had […]

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KDM6B histone demethylase is an epigenetic regulator of estrogen receptor β expression in human pleural mesothelioma

Epigenomics 2016 August 16 [Epub ahead of print] [Link] Manente AG, Pinton G, Zonca S, Tavian D, Habib T, Jithesh PV, Fennell D, Nilsson S5, Moro Abstract AIM: To assess the correlation between KDM6B and estrogen receptor β (ERβ) expression in malignant pleural mesothelioma (MPM). MATERIALS & METHODS: We evaluated gene expression by in silico […]

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Asbestos exposure and histological subtype of malignant mesothelioma

Occupational and Environmental Medicine 2016 August 19 [Epub ahead of print] [Link] Franklin P, Alfonso H, Reid A, Olsen N, Shilkin KB, Brims F, de Klerk N, Musk AW Abstract BACKGROUND: Malignant mesothelioma (MM) has distinct histological subtypes (epithelioid, sarcomatoid and biphasic) with variable behaviour and prognoses. It is well recognised that survival time varies […]

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