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Curated Journal Articles on Mesothelioma

Category Archives: Extrapleural Pneumonectomy (EPP)

Malign pleural mesothelioma – so far an undefeated tumor

Vnitrni lekarstvi 2018 [Link] Kolek V. Abstract Malign pleural mesothelioma is the most frequent primary tumor of the pleura of high aggressiveness. Its most frequent cause is contact with asbestos and, although working with asbestos is already prohibited in developed countries, its incidence is on the increase so far. Diagnostics primarily considers anamnesis, clinical symptoms […]

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Radical multimodality therapy for malignant pleural mesothelioma

The Cochrane Database of Systematic Reviews 2018 January 8 [Epub ahead of print] [Link] Abdel-Rahman O, Elsayed Z, Mohamed H, Eltobgy M Abstract BACKGROUND: Malignant pleural mesothelioma is an almost always fatal tumour, for which palliative platinum-based chemotherapy is currently the standard treatment. Multimodal therapeutic strategies incorporating surgery, radiation therapy or photodynamic therapy and chemotherapy […]

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Proton Therapy for Malignant Pleural Mesothelioma: A Three Case Series Describing the Clinical and Dosimetric Advantages of Proton-Based Therapy

Cureus 2017 September [Link] Lee H, Zeng J, Bowen SR, Rengan R Abstract Malignant pleural mesothelioma (MPM) is a malignancy of the pleural cavity that typically presents at an advanced stage. Due to its large, circumferential clinical target volume (CTV) and proximity to major structures, including the heart and contralateral lung, delivering hemithoracic intensity-modulated radiotherapy […]

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Video assisted thoracoscopic and open chest surgery in diagnosis and treatment of malignant pleural diseases

Journal of Visualized Surgery 2017 June 22 [Link] Perikleous P, Waller DA Abstract Parenchymal cancers of lung, breast, gastrointestinal tract and ovaries as well as lymphomas and mesotheliomas are among the most common cancer types causing malignant effusions, though almost all tumour types have been reported to cause a malignant effusion. The prognosis heavily depends […]

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Treatment for recurrence after extrapleural pneumonectomy for malignant pleural mesothelioma: A single institution experience

Thoracic Cancer 2013 February [Link] Okamoto T, Yano T, Haro A, Yoshida T, Kohno M, Maehara Y Abstract BACKGROUND:   Malignant pleural mesothelioma (MPM) is a relatively rare, aggressive neoplasm associated with asbestos exposure. Extrapleural pneumonectomy (EPP) is often performed for resectable MPM as part of a multidisciplinary treatment; however, available data on treatments for […]

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Radiotherapy for the treatment of malignant pleural mesothelioma

The Lancet. Oncology 2017 September [Link] Perrot M1, Wu L, Wu M, Cho BCJ Abstract Malignant pleural mesothelioma is an aggressive disease that continues to be associated with poor outcomes. Although, traditionally this disease is considered to be resistant to radiotherapy, more recent evidence suggests that radiotherapy can produce positive outcomes. Over the past 15 […]

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Pathological complete response in malignant pleural mesothelioma patients following induction chemotherapy: Predictive factors and outcomes

Lung Cancer 2017 September [Epub 2017 July 13] [Link] Lau B, Kumar S, Yan T, Burn J, Kennedy C, McLean J, Boyer M, McCaughan B, Kao S Abstract A small proportion of patients with malignant pleural mesothelioma (MPM) achieve pathological complete response (CR) following treatment with current practice induction chemotherapy. Our analysis of 58 patients […]

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National Cancer Data Base Report on Pneumonectomy Versus Lung-Sparing Surgery for Malignant Pleural Mesothelioma

Journal of Thoracic Oncology 2017 August 23 [Epub ahead of print] [Link] Verma V, Ahern CA, Berlind CG, Lindsay WD, Sharma S, Shabason J, Culligan MJ, Grover S, Friedberg JS, Simone CB Abstract INTRODUCTION: Controversy exists regarding the optimal surgical technique for malignant pleural mesothelioma (MPM). We evaluated national practice patterns and outcomes of MPM […]

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Functional image guided radiation therapy planning in volumetric modulated arc therapy for patients with malignant pleural mesothelioma

Advances in Radiation Oncology [2017 February] [Link] Doi Y, Kimura T, Nakashima T, Takeuchi Y, Takahashi I, Nishibuchi I, Murakami Y, Nagata Y Abstract PURPOSE: To investigate the incorporation of functional lung image-derived low-attenuation area (LAA) based on 4-dimensional computed tomography (4D-CT) in volumetric modulated arc therapy (VMAT) planning for patients with malignant pleural mesothelioma […]

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Surgery as part of radical treatment for malignant pleural mesothelioma

Current Opinion in Pulmonary Medicine 2017 June [Link] Waller DA, Tenconi S Abstract PURPOSE OF REVIEW: To review the latest developments in surgery for malignant pleural mesothelioma both in patient selection, surgical technique, and strategy. RECENT FINDINGS: The International Association for the Study of Lung Cancer mesothelioma staging project has produced data to inform the […]

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