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Curated Journal Articles on Mesothelioma

Category Archives: Surgery

Surgery or surgeries used in the treatment of malignant mesothelioma.

Influence of Pleurectomy and Decortication in Health-Related Quality of Life Among Patients with Malignant Pleural Mesothelioma.

World Journal of Surgery 2017 September [Epub ahead of print] [Link] Vigneswaran WT, Kircheva DY, Rodrigues AE, Watson S, Celauro AD, Rose B, Kindler HL, Husain AN Abstract BACKGROUND: Complete macroscopic resection surgery, pleurectomy and decortication (PD) improve survival in selected patients with malignant pleural mesothelioma (MPM). Yet its value has been questioned because of […]

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Soluble Mesothelin-Related Peptides to Monitor Recurrence After Resection of Pleural Mesothelioma

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Treatment for recurrence after extrapleural pneumonectomy for malignant pleural mesothelioma: A single institution experience

Thoracic Cancer 2013 February [Link] Okamoto T, Yano T, Haro A, Yoshida T, Kohno M, Maehara Y Abstract BACKGROUND:   Malignant pleural mesothelioma (MPM) is a relatively rare, aggressive neoplasm associated with asbestos exposure. Extrapleural pneumonectomy (EPP) is often performed for resectable MPM as part of a multidisciplinary treatment; however, available data on treatments for […]

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Oncolytic Viral Therapy for Mesothelioma

Frontiers in Oncology 2017 August 24 [Link] Pease DF, Kratzke RA Abstract The limited effectiveness of conventional therapy for malignant pleural mesothelioma demands innovative approaches to this difficult disease. Even with aggressive multimodality treatment of surgery, radiation, and/or chemotherapy, the median survival is only 1-2 years depending on stage and histology. Oncolytic viral therapy has emerged […]

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Radiotherapy for the treatment of malignant pleural mesothelioma

The Lancet. Oncology 2017 September [Link] Perrot M1, Wu L, Wu M, Cho BCJ Abstract Malignant pleural mesothelioma is an aggressive disease that continues to be associated with poor outcomes. Although, traditionally this disease is considered to be resistant to radiotherapy, more recent evidence suggests that radiotherapy can produce positive outcomes. Over the past 15 […]

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Near-Infrared Intraoperative Imaging Can Successfully Identify Malignant Pleural Mesothelioma After Neoadjuvant Chemotherapy

Molecular Imaging 2017 January-December [Link] Predina JD, Newton A, Kennedy G, Lee MK, Singhal S Abstract Malignant pleural mesothelioma is a deadly disease. Complete surgical resection provides patients with the best opportunity for long-term survival. Unfortunately, identification of disease during resection can be challenging. In this report, we describe successful intraoperative utilization of the near-infrared […]

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The role of radical radiotherapy in the management of malignant pleural mesothelioma: A systematic review

Radiotherapy and Oncology 2017 August [Epub ahead of print] [Link] Ashton M1, O’Rourke N2, Currie S2, Rimner A3, Chalmers A Abstract Malignant pleural mesothelioma (MPM) is a devastating disease with limited treatment options and a dismal prognosis. Attempts to employ radical radiotherapy in this disease have been limited by the complex shape of the pleura […]

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Malignant pleural mesothelioma – Pleural cavity irradiation after decortication with helical tomotherapy

Reports of Practical Oncology and Radiotherapy 2017 September [Epub 2017 August 11] [Link] Harrabi SB, Koerber SA, Adeberg S, Katayama S, Herfarth K, Debus J, Sterzing F Abstract BACKGROUND: Malignant pleural mesothelioma (MPM) is a rare and aggressive disease that poses a treatment challenge in spite of recent technical developments. The aim of this retrospective […]

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Pathological complete response in malignant pleural mesothelioma patients following induction chemotherapy: Predictive factors and outcomes

Lung Cancer 2017 September [Epub 2017 July 13] [Link] Lau B, Kumar S, Yan T, Burn J, Kennedy C, McLean J, Boyer M, McCaughan B, Kao S Abstract A small proportion of patients with malignant pleural mesothelioma (MPM) achieve pathological complete response (CR) following treatment with current practice induction chemotherapy. Our analysis of 58 patients […]

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National Cancer Data Base Report on Pneumonectomy Versus Lung-Sparing Surgery for Malignant Pleural Mesothelioma

Journal of Thoracic Oncology 2017 August 23 [Epub ahead of print] [Link] Verma V, Ahern CA, Berlind CG, Lindsay WD, Sharma S, Shabason J, Culligan MJ, Grover S, Friedberg JS, Simone CB Abstract INTRODUCTION: Controversy exists regarding the optimal surgical technique for malignant pleural mesothelioma (MPM). We evaluated national practice patterns and outcomes of MPM […]

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