Training and validation of a knowledge-based dose-volume histogram predictive model in the optimisation of intensity-modulated proton and volumetric modulated arc photon plans for pleural mesothelioma patients

Radiation Oncology 2022 August 26 [Link] Davide Franceschini, Luca Cozzi, Antonella Fogliata, Beatrice Marini, Luciana Di Cristina, Luca Dominici, Ruggero Spoto, Ciro Franzese, Pierina Navarria, Tiziana Comito, Giacomo Reggiori, Stefano Tomatis, Marta Scorsetti Abstract Background: To investigate the performance of a narrow-scope knowledge-based RapidPlan (RP) model for optimisation of intensity-modulated proton therapy (IMPT) and volumetric…

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Proton beam therapy for malignant pleural mesothelioma.

Translational Lung Cancer Research 2018 April 7 [Link] Badiyan SN, Molitoris JK, Zhu M, Glass E, Diwanji T, Simone CB Abstract Malignant pleural mesothelioma (MPM) is a rare disease with a poor prognosis. Surgical techniques have made incremental improvements over the last few decades while new systemic therapies, including immunotherapies, show promise as potentially effective…

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Long-term mortality from pleural and peritoneal cancer after exposure to asbestos: Possible role of asbestos clearance

International Journal of Cancer. 2008 Jun 4. [Epub ahead of print] [Link] Barone-Adesi F, Ferrante D, Bertolotti M, Todesco A, Mirabelli D, Terracini B, Magnani C. Unit of Cancer Epidemiology, CeRMS and Center for Oncologic Prevention Piemonte, University of Turin, Turin, Italy. Abstract Models based on the multistage theory of carcinogenesis predict that the rate…

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The potential of proton beam radiation therapy in lung cancer (including mesothelioma)

Acta Oncologica. 2005 Dec;44(8):881-883. [Link] Bjelkengren G, Glimelius B. Department of Oncology, University Hospital, Malmo, Sweden. Abstract A Swedish group of oncologists and hospital physicists have estimated the number of patients in Sweden suitable for proton beam therapy. The estimations have been based on current statistics of tumour incidence, number of patients potentially eligible for…

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