Single-institution experience of intensity-modulated radiotherapy for malignant pleural mesothelioma at University of Catania

Future Oncology 2018 February 5 [Link] Spatola C et. al. Abstract The multimodal approach to malignant pleural mesothelioma is gradually becoming the standard of care for this disease in patients with good performance status. Materials & methods: We report our experience concerning eight cases treated with the use of static step-and-shoot intensity-modulated radiotherapy to the…

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Proton Therapy for Malignant Pleural Mesothelioma: A Three Case Series Describing the Clinical and Dosimetric Advantages of Proton-Based Therapy

Cureus 2017 September [Link] Lee H, Zeng J, Bowen SR, Rengan R Abstract Malignant pleural mesothelioma (MPM) is a malignancy of the pleural cavity that typically presents at an advanced stage. Due to its large, circumferential clinical target volume (CTV) and proximity to major structures, including the heart and contralateral lung, delivering hemithoracic intensity-modulated radiotherapy…

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Radiotherapy for the treatment of malignant pleural mesothelioma

The Lancet. Oncology 2017 September [Link] Perrot M1, Wu L, Wu M, Cho BCJ Abstract Malignant pleural mesothelioma is an aggressive disease that continues to be associated with poor outcomes. Although, traditionally this disease is considered to be resistant to radiotherapy, more recent evidence suggests that radiotherapy can produce positive outcomes. Over the past 15…

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Malignant pleural mesothelioma – Pleural cavity irradiation after decortication with helical tomotherapy

Reports of Practical Oncology and Radiotherapy 2017 September [Epub 2017 August 11] [Link] Harrabi SB, Koerber SA, Adeberg S, Katayama S, Herfarth K, Debus J, Sterzing F Abstract BACKGROUND: Malignant pleural mesothelioma (MPM) is a rare and aggressive disease that poses a treatment challenge in spite of recent technical developments. The aim of this retrospective…

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High-dose palliative radiotherapy for malignant pleural mesothelioma

Journal of Medical Imaging and Radiation Oncology 2017 July 20 [Epub ahead of print] [Link] Foroudi F, Smith JG, Putt F, Wada M Abstract INTRODUCTION: High-dose radiotherapy to the hemithorax for patients with malignant pleural mesothelioma is a controversial treatment. Between 2003 and 2013 our institution had a policy of giving hemithoracic radiotherapy to at…

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Radio-immunotherapy and chemo-immunotherapy as a novel treatment paradigm in malignant pleural mesothelioma

Translational Lung Cancer 2017 June [Link] Wu L, de Perrot M Abstract Malignant pleural mesothelioma (MPM) is an aggressive neoplasm with poor outcome. Novel radical radiation techniques using intensity modulated radiation therapy (IMRT) have become an important component of therapy in mesothelioma. Immunotherapy also provides new therapeutic options. However, how best to integrate immunotherapy with…

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A pilot study of volumetric-modulated arc therapy for malignant pleural mesothelioma

Journal of Applied Clinical Medical Physics 2016 March [Link] Runxiao L1, Yankun C1, Lan W Abstract Malignant pleural mesothelioma (MPM) is an extremely difficult disease to treat. This pilot study investigates the feasibility of using volumetric-modulated arc therapy (VMAT) for malignant pleural mesothelioma (MPM), and compares VMAT to static field intensity-modulated radiotherapy (IMRT) for five…

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Role of postoperative radiotherapy in the management of malignant pleural mesothelioma : A propensity score matching of the SEER database

Clinical Oncology Department, Ain Shams University [2017 January 2] [Link] Abdel-Rahman O Abstract INTRODUCTION: This study assessed the prognostic impact of postoperative radiotherapy in patients with surgically resected malignant pleural mesothelioma (MPM). METHODS: MPM patients diagnosed between 2000 and 2013 were identified from the SEER (Surveillance, Epidemiology, and End Results) database. A propensity-matched analysis was…

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