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Curated Journal Articles on Mesothelioma

Category Archives: Next Generation Sequencing (NGS)

Genome Evolution Analysis of Recurrent Testicular Malignant Mesothelioma by Whole-Genome Sequencing

Cellular Physiology and Biochemistry 2018 January 15 [Epub ahead of print] [Link] Zhang S, Zhang Q, Sun Q, Tang J, Chen J, Ji N, Zheng Y, Fang F, Lei W, Li P, Zhang N Abstract BACKGROUND/AIMS: Malignant mesothelioma of the tunica vaginalis testis is a rare and lethal disease. The genomic characteristics and genetic changes […]

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Germline and somatic variant identification using BGISEQ-500 and HiSeq X Ten whole genome sequencing

PloS one 2018 January [Link] Patch AM et. al. Abstract Technological innovation and increased affordability have contributed to the widespread adoption of genome sequencing technologies in biomedical research. In particular large cancer research consortia have embraced next generation sequencing, and have used the technology to define the somatic mutation landscape of multiple cancer types. These […]

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Identification of ALK Rearrangements in Malignant Peritoneal Mesothelioma

JAMA Oncology 2017 September [Epub ahead of print] [Link] Hung YP, Dong F, Watkins JC, Nardi V, Bueno R, Dal Cin P, Godleski JJ, Crum CP, Chirieac LR Abstract IMPORTANCE: Malignant peritoneal mesothelioma is a rare, aggressive tumor arising from the peritoneal lining, induced by asbestos, therapeutic radiation, or germline mutations. Nevertheless, the molecular features […]

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Identification of MiR-21-5p as a Functional Regulator of Mesothelin Expression Using MicroRNA Capture Affinity Coupled with Next Generation Sequencing

PLoS One 2017 January 26 [

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Genomic Landscape of Malignant Mesotheliomas

Molecular Cancer Therapeutics 2016 August 9 [Epub ahead of print] [Link] Kato S, Tomson BN, Buys TP, Elkin SK, Carter JL, Kurzrock R Abstract Understanding the genomic landscape of malignant mesothelioma may identify novel molecular drivers of this ultra-rare disease, which can lead to an expanded roster of targeted therapies and clinical trial options for […]

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