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Curated Journal Articles on Mesothelioma

Category Archives: Vinorelbine

BAMLET kills chemotherapy-resistant mesothelioma cells, holding oleic acid in an activated cytotoxic state.

PloS One 2018 August 29 [Link] Rath EM, Cheng YY, Pinese M, Sarun KH, Hudson AL, Weir C, Wang YD, Håkansson AP, Howell VM, Liu GJ, Reid G, Knott RB, Duff Abstract Malignant pleural mesothelioma is an aggressive cancer with poor prognosis. Here we have investigated in vitro efficacy of BAMLET and BLAGLET complexes (anti-cancer […]

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High RRM1 Expression Is Associated with Adverse Outcome in Patients with Cisplatin/Vinorelbine-treated Malignant Pleural Mesothelioma

Anticancer Research 2015 December [Link] Zimling ZG, Santoni-Rugiu E, Bech C, Sørensen JB. Abstract Background/Aim A possible predictive impact of ribonucleotide-reductase subunit-1 (RRM1) on vinorelbine efficacy in non-small cell lung cancer (NSCLC) has been previously reported. The present study aimed to further explore this finding in malignant pleural mesothelioma (MPM). Materials and Methods Seventy-one patients […]

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Systemic Treatments for Mesothelioma: Standard and Novel

Current Treatment Options in Oncology. 2008 Jun;9(2-3):171-9. Epub 2008 Sep 3. [Link] Kindler HL. Section of Hematology/Oncology, University of Chicago, Chicago, IL 60637, USA. hkindler@medicine.bsd.uchicago.edu Abstract Systemic therapy is the only treatment option for the majority of mesothelioma patients, for whom age, co-morbid medical illnesses, non-epithelial histology, and locally advanced disease often preclude surgery. For […]

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Cisplatin and vinorelbine first-line chemotherapy in non-resectable malignant pleural mesothelioma

British Journal of Cancer. 2008 Jun 10. [Epub ahead of print] [Link] Sørensen JB, Frank H, Palshof T. 1Department Oncology, Finsen Centre/National University Hospital, 9 Blegdamsvej, Copenhagen DK-2100, Denmark. Abstract The aim was to evaluate the activity of cisplatin and vinorelbine in previously untreated, inoperable patients having histologically verified malignant pleural mesothelioma (MPM), normal organ […]

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Response of a Patient with Pleural and Peritoneal Mesothelioma after Second-Line Chemotherapy with Lipoplatin and Gemcitabine

Oncology. 2007;73:426-429. [Link] Karpathiou G, Argiana E, Koutsopoulos A, Froudarakis ME. Department of Pneumonology, Medical School Democritus University of Thrace, Alexandroupolis, Greece. Abstract We report the case of a 56-year-old patient with malignant pleural mesothelioma of epithelial type, who responded to second-line chemotherapy with lipoplatin plus gemcitabine. Diagnosis and staging of the disease was done […]

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The efficacy and safety of weekly vinorelbine in relapsed malignant pleural mesothelioma

Lung Cancer. 2008 May 15. [Epub ahead of print] [Link] Stebbing J, Powles T, McPherson K, Shamash J, Wells P, Sheaff MT, Slater S, Rudd RM, Fennell D, Steele JP. Department of Medical Oncology, St. Bartholomew’s Hospital, West Smithfield, London EC1A 7BE, UK. Abstract Malignant pleural mesothelioma (MPM) is a rapidly progressive invariably lethal tumor. […]

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Active symptom control with or without chemotherapy in the treatment of patients with malignant pleural mesothelioma (MS01): a multicentre randomised trial

Lancet. 2008 May 17;371(9625):1685-1694. [Link] Muers MF, Stephens RJ, Fisher P, Darlison L, Higgs CM, Lowry E, Nicholson AG, O’Brien M, Peake M, Rudd R, Snee M, Steele J, Girling DJ, Nankivell M, Pugh C, Parmar MK; on behalf of the MS01 Trial Management Group. Leeds General Infirmary, Leeds, UK. Abstract Background: Malignant pleural mesothelioma […]

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Gemcitabine and vinorelbine in pemetrexed-pretreated patients with malignant pleural mesothelioma

Cancer. 2008 Feb 19 [Epub ahead of print] [Link] Zucali PA, Ceresoli GL, Garassino I, De Vincenzo F, Cavina R, Campagnoli E, Cappuzzo F, Salamina S, Soto Parra HJ, Santoro A. Department of Medical Oncology and Hematology, Humanitas Clinical Institute of Rozzano, Milan, Italy. Abstract Background: Pemetrexed-cisplatin chemotherapy is the standard of care in the […]

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Cost-effectiveness of pemetrexed plus cisplatin: malignant pleural mesothelioma treatment in UK clinical practice

Value in Health. 2008 Jan-Feb;11(1):4-12. [Link] Cordony A, Le Reun C, Smala A, Symanowski JT, Watkins J. M-TAG Pty Ltd, A Unit of IMS Health, St Leonards, NSW, Australia. acordony@au.imshealth.com Abstract Objectives: Findings from the largest randomized phase III trial in patients with unresectable malignant pleural mesothelioma (EMPHACIS study; n = 448) were used to […]

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A case of malignant mesothelioma presenting with recurrent pneumothorax

Nihon Kokyuki Gakkai Zasshi. 2006 Nov;44(11):807-11. [Link] Katayam N, Tokuda A, Nakatsumi Y, Oribe Y, Fujimura M. Department of Respiratory Medicine, Kanazawa Municipal Hospital. Abstract A 71-year-old man was found to have right hydropneumothorax by chest X-ray film on a regular checkup. Thoracic drainage and bullectomy by thoracoscopy did not improve the pneumothorax, so pleurodesis […]

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