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Curated Journal Articles on Mesothelioma

Category Archives: Doxorubicin

Long-term regional chemotherapy for patients with epithelial malignant peritoneal mesothelioma results in improved survival

European Journal of Surgical Oncology 2017 Janury 29 [Epub ahead of print] [Link] Sugarbaker PH, Chang D Abstract PURPOSE: Malignant peritoneal mesothelioma (MPM) is a rare disease with about 300 new cases per year in the USA. Its natural history is described as local progression within the peritoneal space in the absence of liver metastases […]

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Third-line chemotherapy with carboplatin, gemcitabine and liposomised doxorubicin for malignant pleural mesothelioma

Medical Oncology 2015 February [Link] de Lima VA, Sorensen JB. Abstract There is no well-defined standard third-line chemotherapy for advanced malignant pleural mesothelioma (MPM). However, combination of carboplatin, liposomised doxorubicin (Caelyx) and gemcitabine (CCG regimen) has revealed noteworthy activity when used as first-line treatment. The aim of this study is to assess efficacy and toxicity […]

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Treatment of malignant pleural mesothelioma with carboplatin, liposomized doxorubicin, and gemcitabine: a phase II study

Journal of Thoracic Oncology. 2008 Nov;3(11):1325-31. [Link] Hillerdal G, Sorensen JB, Sundström S, Riska H, Vikström A, Hjerpe A. Department of Lung Medicine and Allergology, Karolinska University Hospital, Solna, Stockholm, Sweden. gunnar.hillerdal@karolinska.se Abstract Background: Malignant pleural mesothelioma has a poor prognosis and there is limited effect of treatment. The Nordic Mesothelioma groups decided in the […]

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Peritoneal Mesothelioma

Current Treatment Options in Oncology. 2008 Jun;9(2-3):180-90. Epub 2008 Oct 8. [Link] Hesdorffer ME, Chabot J, DeRosa C, Taub R. Mesothelioma Applied Research Foundation, Santa Barbara, CA, USA. mhesdorer@curemeso.org Abstract Opinion statement: Malignant peritoneal mesothelioma (MPM) is an aggressive neoplasm that rapidly spreads within the confines of the abdominal cavity to involve most accessible peritoneal […]

Successful palliation of malignant ascites from peritoneal mesothelioma by laparoscopic intraperitoneal hyperthermic chemotherapy

Surgical Laparoscopy, Endoscopy & Percutaneous Techniques. 2008 Aug;18(4):426-8. [Link] Patriti A, Cavazzoni E, Graziosi L, Pisciaroli A, Luzi D, Gullà N, Donini A. Section of General and Emergency Surgery, Department of Surgery, University of Perugia, Perugia, Italy. albertopatriti@gmail.com Abstract A variety of options have been proposed to treat malignant ascites but most of them have […]

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A pharmacologic analysis of intraoperative intracavitary cancer chemotherapy with doxorubicin

Cancer Chemotherapy and Pharmacology. 2008 Jul 25. [Epub ahead of print] [Link] Van der Speeten K, Stuart OA, Mahteme H, Sugarbaker PH. Department of Surgical Oncology, Ziekenhuis Oost-Limburg, Schiepse Bos 6, 3600, Genk, Belgium, kurt.vanderspeeten@zol.be. Abstract Purpose: A pharmacologic analysis of intracavitary doxorubicin in the treatment of patients with intracavitary cancer dissemination was performed to […]

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Phase I trial of pegylated liposomal doxorubicin with hyperthermic intraperitoneal chemotherapy in patients undergoing cytoreduction for advanced intra-abdominal malignancy

Annals of Surgical Oncology. 2008 May;15(5):1407-13. Epub 2007 Dec 22. [Link] Harrison LE, Bryan M, Pliner L, Saunders T. Division of Surgical Oncology, UMDNJ-New Jersey Medical School, 185 South Orange Ave, Newark, NJ 07103, USA. L.Harrison@umdnj.edu Abstract Background: Cytoreduction coupled with hyperthermic intraperitoneal chemotherapy (HIPEC) is an attractive treatment option for a select group of […]

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Multicystic peritoneal mesothelioma treated by surgical cytoreduction and hyperthermic intra-peritoneal chemotherapy (HIPEC)

In Vivo. 2008 Jan-Feb;22(1):153-7. [Link] Baratti D, Kusamura S, Sironi A, Cabras A, Fumagalli L, Laterza B, Deraco M. Department of Surgery, National Cancer Institute, Milan, Italy. Abstract Background: Multicystic peritoneal mesothelioma (MPM) is an extremely uncommon lesion with uncertain malignant potential. Multiple recurrences after surgical interventions and transition to aggressive malignancies have been reported. […]

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Asbestos induces doxorubicin resistance in MM98 mesothelioma cells via HIF-1{alpha}

European Respiratory Journal. 2008 Apr 2 [Epub ahead of print] [Link] Riganti C, Doublier S, Aldieri E, Orecchia S, Betta PG, Gazzano E, Ghigo D, Bosia A. Biology and Biochemistry, University of Torino; and Research Center on Experimental Medicine (CeRMS), Via Santena 5/bis, 10126 Torino, Italy. Abstract Human malignant mesothelioma (HMM), which is strongly related […]

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Combined resection, intraperitoneal chemotherapy, and whole abdominal radiation for the treatment of malignant peritoneal mesothelioma

American Journal of Clinical Oncology. 2008 Feb;31(1):49-54 [Link] Hesdorffer ME, Chabot JA, Keohan ML, Fountain K, Talbot S, Gabay M, Valentin C, Lee SM, Taub RN. Division of Oncology, Columbia University New York, New York, USA. mhesdorffer@curemeso.org Abstract Objective: We report a single-institution Phase I or II trial of surgical debulking, intraperitoneal chemotherapy, and immunotherapy […]

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