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Curated Journal Articles on Mesothelioma

Category Archives: Pleural Effusion

An abnormal accumulation of fluid in the pleural space.

Chest ultrasonography in health surveillance of asbestos-related lung diseases.

Toxicology and Industrial Health 2017 January [Epub ahead ofprint] [Link] Smargiassi A, Pasciuto G, Pedicelli I, Lo Greco E, Calvello M, Inchingolo R, Schifino G, Capoluongo P, Patriciello P, Manno M, Cirillo A, Corbo GM, Soldati G, Iavicoli I Abstract OBJECTIVES: Exposure to asbestos fibers can lead to different lung diseases, such as pleural thickening […]

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Pleural fluid cytology samples in cases of suspected lung cancer: An experience from a tertiary care centre

Diagnostic Cytopathology 2017 January 23 [Epub ahead of print] [Link] Kaur G, Nijhawan R, Gupta N, Singh N, Rajwanshi A Abstract OBJECTIVE: Pleural effusion is present in some patients with lung carcinoma. This study was undertaken to evaluate the role of pleural fluid cytology in suspected cases of lung carcinoma. METHODS: In this prospective study, […]

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Flex-rigid pleuroscopic biopsy with the SB knife Jr is a novel technique for diagnosis of malignant or benign fibrothorax

Journal of Thoracic Disease 2016 November [Link] Wang XB, Yin Y, Miao Y, Eberhardt R, Hou G, Herth FJ, Kang J Abstract Diagnosing pleural effusion is challenging, especially in patients with malignant or benign fibrothorax, which is difficult to sample using standard flexible forceps (SFF) via flex-rigid pleuroscopy. An adequate sample is crucial for the […]

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Malignant pleural fluid from mesothelioma has potent biological activities

Respirology 2017 January [Epub 2016 August 25] [Link] Cheah HM, Lansley SM, Varano Della Vergiliana JF, Tan AL, Thomas R, Leong SL, Creaney J, Lee YC Abstract BACKGROUND AND OBJECTIVE: Malignant pleural effusion (MPE) affects >90% of mesothelioma patients. Research on MPE has focused on its physical impact on breathlessness; MPE is rich in growth […]

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The role of surgical intervention in lung cancer with carcinomatous pleuritis

Journal of Thoracic Disease 2016 November [Link] Fukui T, Yokoi K Abstract Patients with non-small cell lung cancer (NSCLC) associated with carcinomatous pleuritis are currently classified as having stage IV disease per the 7th edition of the tumor-node-metastasis (TNM) system, which means that the disease is deemed incurable. In fact, the 5-year survival rate of […]

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Malignant pleural mesothelioma: an update on investigation, diagnosis and treatment

European Respiratory Review 2016 December [Link] Bibby AC, Tsim S, Kanellakis N, Ball H, Talbot DC, Blyth KG, Maskell NA, Psallidas Abstract Malignant pleural mesothelioma is an aggressive malignancy of the pleural surface, predominantly caused by prior asbestos exposure. There is a global epidemic of malignant pleural mesothelioma underway, and incidence rates are predicted to […]

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Diagnostic Utility of Pleural Fluid Cell Block versus Pleural Biopsy Collected by Flex-Rigid Pleuroscopy for Malignant Pleural Disease: A Single Center Retrospective Analysis

PLoS One 2016 November 23 [Link] Miyoshi S, Sasada S, Izumo T, Matsumoto Y, Tsuchida T Abstract BACKGROUND: Some trials recently demonstrated the benefit of targeted treatment for malignant disease; therefore, adequate tissues are needed to detect the targeted gene. Pleural biopsy using flex-rigid pleuroscopy and pleural effusion cell block analysis are both useful for […]

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Management of malignant pleural mesothelioma – part 1: epidemiology, diagnosis, and staging : Consensus of the Austrian Mesothelioma Interest Group (AMIG)

Wiener Klinische Wochenschrift 2016 September 12 [Epub ahead of print] [Link] Geltner C1, Errhalt P, Baumgartner B, Ambrosch G, Machan B, Eckmayr J, Klikovits T, Hoda MA, Popper H, Klepetko W; Austrian Mesothelioma Interest Group (AMIG) Abstract Malignant pleural mesothelioma is a rare malignant disease that in the majority of cases is associated with asbestos […]

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Pleural irregularities and mediastinal pleural involvement in early stages of malignant pleural mesothelioma and benign asbestos pleural effusion

European Journal of Radiology 2016 September 8 [Epub 2016 June 21] [Link] Kato K, Gemba K, Fujimoto N, Aoe K, Takeshima Y, Inai K, Kishimoto T Abstract OBJECTIVE: To elucidate differences in the level and localization of pleural irregularities in early malignant pleural mesothelioma (eMPM) and benign asbestos pleural effusion (BAPE) using CT. STUDY DESIGN: […]

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CD24 is highly useful in differentiating high-grade serous carcinoma from benign and malignant mesothelial cells

Human Pathology 2016 August 30 [Epub ahead of print] [Link] Davidson B Abstract CD24 was previously shown to be overexpressed in high-grade serous carcinoma (HGSC) effusions compared to malignant mesothelioma (MM) in gene expression array analysis. The present study validated this observation in a large series consisting of both effusions and surgical specimens. Effusions (n=206; […]

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