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Curated Journal Articles on Mesothelioma

Category Archives: Pleural Effusion

An abnormal accumulation of fluid in the pleural space.

Biomarkers for early diagnosis of malignant mesothelioma: Do we need another moonshot?

Oncotarget 2017 May 17 [Epub ahead of print] [Link] Lagniau S, Lamote K, van Meerbeeck JP2, Vermaelen KY Abstract Early diagnosis of malignant pleural mesothelioma (MPM) is a challenge for clinicians. The disease is usually detected in an advanced stage which precludes curative treatment. We assume that only new and non-invasive biomarkers allowing earlier detection […]

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Improved diagnosis and prognostication of patients with pleural malignant mesothelioma using biomarkers in pleural effusions and peripheral blood samples – a short report

Cell Oncology 2017 June 2 [Epub ahead of print] [Link] Beije N, Kraan J, den Bakker MA, Maat APWM, van der Leest C, Cornelissen R, Van NM, Martens JWM, Aerts JGJV, Sleijfer S Abstract PURPOSE: There is a lack of robust and clinically utilizable markers for the diagnosis and prognostication of malignant pleural mesothelioma (MPM). […]

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CD44 and its ligand hyaluronan as potential biomarkers in malignant pleural mesothelioma: evidence and perspectives.

Respiratory Research 2017 April [Link] Cortes-Dericks L, Schmid RA Abstract Malignant pleural mesothelioma (MPM) is a rare and highly drug resistant tumor arising from the mesothelial surfaces of the lung pleura. The standard method to confirm MPM is the tedious, time-consuming cytological examination of cancer biopsy. Biomarkers that are detectable in pleural effusion or patient […]

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Prostaglandin E2-mediated adenosinergic effects on CD14+ cells: Self-amplifying immunosuppression in cancer

Oncoimmunology 2016 December [a href=”https://www.ncbi.nlm.nih.gov/pubmed/28344879″>Link] Al-Taei S, Salimu J, Spary LK, Clayton A, Lester JF, Tabi Z Abstract CD39 and CD73 are surface-expressed ectonucleotidases that hydrolyze ATP in a highly regulated, serial manner into ADP, AMP and adenosine. The end product, adenosine, has both tumor-promoting and immunosuppressive effects. The aim of this study was to […]

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Comparison of the Diagnostic Performance of Fibulin-3 and Mesothelin in Patients with Pleural Effusions from Malignant Mesothelioma.

Anticancer Research 2017 March [a href=”https://www.ncbi.nlm.nih.gov/pubmed/28314308″>Link] Battolla E, Canessa PA, Ferro P, Franceschini MC, Fontana V, Dessanti P, Pinelli V, Morabito A, Fedeli F, Pistillo MP5, Roncella S Abstract BACKGROUND: In the literature, there exist conflicting data on the value of fibulin-3 (FBLN3) for the diagnosis of pleural effusion (PE) in malignant pleural mesothelioma (MPM). […]

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Mesothelioid reaction following talc pleurodesis: a case report.

General Thoracic and Cardiovascular Surgery 2017 March [Epub ahead of print] [Link] Faynberg T, Patel N, Nayar AP, Shienbaum AJ Abstract INTRODUCTION: Talc pleurodesis is a well-established procedure performed to obliterate the pleural space to prevent recurrent pleural effusion and/or recurrent pneumothorax. Pleurodesis is commonly accomplished by draining the pleural fluid, if present, followed by […]

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Non-Hodgkin Lymphoma and Pleural Mesothelioma in a Person Exposed to Asbestos

Turk Patologi 2017 February [Epub ahead of print] [Link] Bianchi C, Bianchi T Abstract Non-Hodgkin lymphoma and pleural mesothelioma may co-exist in the same patient. A large cell non-Hodgkin lymphoma of the inguinal lymph nodes was diagnosed in a 73-year-old woman. The patient was treated by chemotherapy. She did not receive radiotherapy. The patient had […]

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Positive pleural cytology is an indicator for visceral pleural invasion in metastatic pleural effusions

Clinical Respiratory Journal 2017 February [Epub ahead of print] [Link] Froudarakis ME, Plojoux J, Kaspi E, Anevlavis S, Laroumagne S, Karpathiou G, Roca E, Adler D, Dutau 2, Astoul P Abstract INTRODUCTION: In case of undiagnosed pleural effusions, it is necessary to conduct thoracentesis with pleural fluid (PF) cytology. Yet, sensitivity of PF cytology is […]

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Aberrant Cytokeratin 20 Reactivity in Epithelioid Malignant Mesothelioma: A Case Report

Applied Immunohistochemistry and Molecular Morphology 2017 February [Epub ahead of print] [Link] Manur R, Lamzabi I Abstract Malignant mesothelioma is an uncommon neoplasm that should be distinguished from the more common pulmonary adenocarcinomas and other metastatic lesions. Although diagnosis is based on morphologic features, immunohistochemical stains such as Calretinin, WT-1, CK-5/6, D2-40, Ber-Ep4, and MOC-31 […]

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Pharmacokinetic evaluation of intrapleural perfusion with hyperthermic chemotherapy using cisplatin in patients with malignant pleural effusion

Lung Cancer (Netherlands) 2017 February [Epub 2016 December 21] [Link] Sakaguchi H, Ishida H, Nitanda H, Yamazaki N, Kaneko K, Kobayashi K Abstract OBJECTIVES: Malignant pleural effusion (MPE) has a poor prognosis. Most patients are treated with tube thoracostomy and sclerotherapy, although its success rate is around 64%. We have investigated intrapleural perfusion with hyperthermic […]

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