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Curated Journal Articles on Mesothelioma

Category Archives: Symptoms & Symptom Management

Early-stage Clinical Characterization of Malignant Pleural Mesothelioma.

In Vivo 2018 September-October [Link] Negi Y, Kuribayashi K, Funaguchi N, Doi H, Mikami K, Minami T, Takuwa T, Yokoi T, Hasegawa S, Ki Abstract BACKGROUND/AIM: A strategy for improving survival of malignant pleural mesothelioma (MPM) patients is earlier diagnosis paired with earlier stage implementation of therapeutic interventions. This study aimed to determine the clinical […]

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Measurement of telomere length in cells from pleural effusion: Asbestos exposure causes telomere shortening in pleural mesothelial cells.

Pathology International 2018 August 10 [Link] Aida S, Aida J, Naoi M, Kato M, Tsuura Y, Natsume I, Takubo K Abstract We estimated the telomere lengths of neoplastic and non-neoplastic mesothelial cells and examined their correlation with asbestos exposure and the expression of markers of mesothelial malignancy. Cell blocks of pleural effusion obtained from 35 […]

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Air in the Pleural Cavity Enhances Detection of Pleural Abnormalities by CT Scan

Chest 2018 June [Link] Fysh ETH, Thomas R, Tobin C, Kuok YJ, Lee YCG Abstract Detection of pleural abnormalities on CT scan is critical in diagnosis of pleural disease. CT scan detects minute parenchymal lung nodules, but often fails to detect similar-sized pleural nodularity. This is likely because the density of the visceral/parietal pleura and […]

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Soluble CD157 in pleural effusions: a complementary tool for the diagnosis of malignant mesothelioma.

Oncotarget 2018 April 27 [Link] Augeri S, Capano S, Morone S, Fissolo G, Giacomino A, Peola S, Drace Z, Rapa I, Novello S, Volante M, Righi L, Ferrero E, Ortolan E, Funaro A Abstract BACKGROUND: CD157/Bst1 glycoprotein is expressed in >85% of malignant pleural mesotheliomas and is a marker of enhanced tumor aggressiveness. RESULTS: In […]

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18F-fluorodeoxyglucose imaging of primary malignant pericardial mesothelioma with concurrent pericardial and pleural effusions and bone metastasis: A case report.

Molecular and Clinical Oncology 2018 June 8 [Link] Li X, Lu R, Zhao Y, Wang F, Shao G Abstract Primary malignant pericardial mesothelioma (PMPM) is an aggressive tumor that originates from the mesothelial cells of the pericardium. PMPM with extensive atrial infiltration and bone metastasis is extremely rare. The diagnosis and staging of PMPM based […]

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Malignant cells from pleural fluids in malignant mesothelioma patients reveal novel mutations

Lung Cancer, Amsterdam, Netherlands Epub 2018 March 9 [Link] Sneddon S, Dick I, Lee YCG, Musk AWB, Patch AM, Pearson JV, Waddell N, Allcock RJN, Holt RA, Robinson BWS, Creaney J Abstract OBJECTIVES: Malignant mesothelioma (MM) is an asbestos related tumour affecting cells of serosal cavities. More than 70% of MM patients develop pleural effusions […]

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The current aetiology of malignant pleural effusion in the Western Cape Province, South Africa

South African Medical Journal 2018 March 28 [Link] Koegelenberg CFN1, Bennji SM, Boer E, Schubert PT, Shaw JA, Allwood BW, Irusen EM Abstract BACKGROUND: Malignant pleural effusion (MPE) represents a very common cause of pleural exudates, and is one of the most challenging pleural disorders to manage. This could be attributed to the paucity of […]

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Malignant pleural mesothelioma: diagnostic value of medical thoracoscopy and long-term prognostic analysis

Pulmonary Medicine 2018 April 3 [Link] Xu LL, Yang Y, Wang Z, Wang XJ, Tong ZH, Shi HZ Abstract BACKGROUND: Malignant pleural mesothelioma (MPM) is marked by its difficult diagnosis and poor prognosis. Medical thoracoscopy (MT) is an effective and safe procedure for the diagnosis of exudative pleural effusions and many factors associated with poor […]

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Randomised controlled trial to compare the diagnostic yield of positron emission tomography CT (PET-CT) TARGETed pleural biopsy versus CT-guided pleural biopsy in suspected pleural malignancy (TARGET trial)

BMJ Open Respiratory Research 2018 February 19 [Link] de Fonseka D, Underwood W, Stadon L, Rahman N, Edey A, Rogers C, Maskell NA Abstract INTRODUCTION: Pleural malignancy, particularly malignant pleural mesothelioma (MPM) is increasing in incidence due to the long latency period from exposure to asbestos to development of the disease. MPM can be challenging […]

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Malignant Pleural Mesothelioma: Are There Imaging Characteristics Associated With Different Histologic Subtypes on Computed Tomography?

Journal of Computer Assisted Tomography 2018 April 2 [Epub ahead of print] [Link] Escalon JG, Harrington KA, Plodkowski AJ, Zheng J, Capanu M, Zauderer MG, Rusch VW, Ginsberg MS Abstract OBJECTIVES: Determine imaging characteristics specific to epithelioid (eMPM), sarcomatoid (sMPM), and biphasic (bMPM) subtypes of malignant pleural mesothelioma (MPM) on computed tomography. METHODS: Preoperative computed […]

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