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Curated Journal Articles on Mesothelioma

Category Archives: Survival

High-dose palliative radiotherapy for malignant pleural mesothelioma

Journal of Medical Imaging and Radiation Oncology 2017 July 20 [Epub ahead of print] [Link] Foroudi F, Smith JG, Putt F, Wada M Abstract INTRODUCTION: High-dose radiotherapy to the hemithorax for patients with malignant pleural mesothelioma is a controversial treatment. Between 2003 and 2013 our institution had a policy of giving hemithoracic radiotherapy to at […]

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Immunotherapy for malignant pleural mesothelioma: current status and future directions

Translational Lung Cancer Research 2017 June [Link] Dozier J1, Zheng H1, Adusumilli PS Abstract Malignant pleural mesothelioma (MPM) has been marked historically by poor prognosis. Current standard of care for this deadly disease results in sub-optimal improvements in overall survival (OS), which has prompted researchers to explore innovative treatment alternatives. Immunotherapy is an emerging therapeutic […]

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Posttranscriptional Regulation Controls Calretinin Expression in Malignant Pleural Mesothelioma

Frontiers in Genetics 2017 May [Link] Kresoja-Rakic J, Sulemani M, Kirschner MB, Ronner M, Reid G, Kao S, Schwaller B, Weder W, Stahel RA, Felley-Bosco E Abstract Calretinin (CALB2) is a diagnostic and prognostic marker in malignant pleural mesothelioma (MPM). We previously reported that calretinin expression is regulated at the mRNA level. The presence of […]

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First-line chemotherapy with pemetrexed plus cisplatin for malignant peritoneal mesothelioma

Expert review of anticancer therapy 2017 June 8 [Epub ahead of print] [Link] Fujimoto E, Kijima T, Kuribayashi K, Negi Y, Kanemura S, Mikami K, Doi H, Kitajima K, Nakano T Abstract BACKGROUND: Mesothelioma of peritoneal origin has wider variation in treatment outcomes than mesothelioma of pleural origin, likely because peritoneal mesothelioma comprises borderline malignant […]

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Deregulation of miRNAs in malignant pleural mesothelioma is associated with prognosis and suggests an alteration of cell metabolism

Scientific Reports 2017 June [

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Synergistic targeting of malignant pleural mesothelioma cells by MDM2 inhibitors and TRAIL agonists

Oncotarget 2017 May 11 [Epub ahead of print] [Link] Urso L, Cavallari I, Silic-Benussi M, Biasini L, Zago G, Calabrese F, Conte PF, Ciminale V, Pasello G Abstract Malignant Pleural Mesothelioma (MPM) is a chemoresistant tumor characterized by low rate of p53 mutation and upregulation of Murine Double Minute 2 (MDM2), suggesting that it may […]

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Improved diagnosis and prognostication of patients with pleural malignant mesothelioma using biomarkers in pleural effusions and peripheral blood samples – a short report

Cell Oncology 2017 June 2 [Epub ahead of print] [Link] Beije N, Kraan J, den Bakker MA, Maat APWM, van der Leest C, Cornelissen R, Van NM, Martens JWM, Aerts JGJV, Sleijfer S Abstract PURPOSE: There is a lack of robust and clinically utilizable markers for the diagnosis and prognostication of malignant pleural mesothelioma (MPM). […]

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The inhibition of FGF receptor 1 activity mediates sorafenib antiproliferative effects in human malignant pleural mesothelioma tumor-initiating cells

Stem cell research & therapy 2017 May 25 [Link] Pattarozzi A, Carra E, Favoni RE, Würth R, Marubbi D, Filiberti RA, Mutti L, Florio T, Barbieri F, Daga A Abstract BACKGROUND: Malignant pleural mesothelioma is an aggressive cancer, characterized by rapid progression and high mortality. Persistence of tumor-initiating cells (TICs, or cancer stem cells) after […]

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Comparison of outcomes following a cytological or histological diagnosis of malignant mesothelioma.

British Journal of Cancer 2017 March 14 [Epub 2017 February 14] [Link] Muruganandan S, Alfonso H, Franklin P, Shilkin K, Segal A, Olsen N, Reid A, de Klerk N, Musk AB, Brims F Abstract BACKGROUND: Survival with the epithelioid subtype of malignant mesothelioma (MM) is longer than the biphasic or sarcomatoid subtypes. There is concern […]

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Pleurectomy-decortication in malignant pleural mesothelioma: are different surgical techniques associated with different outcomes? Results from a multicentre study

European Journal of Cardio-Throacic Surgery 2017 April [Epub ahead of print] [Link] Marulli G, Breda C, Fontana P, Ratto GB, Leoncini G, Alloisio M, Infante M, Luzzi L, Paladini P, Oliaro A, Ruffini E, Benvenuti MR, Pariscenti G, Spaggiari L, Casiraghi M, Rusca M, Carbognani P, Ampollini L, Facciolo F, Leuzzi G, Mucilli F, Camplese […]

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