Comparison of the role of 18 F-fluorodeoxyglucose PET/computed tomography and 68 Ga-labeled FAP inhibitor-04 PET/CT in patients with malignant mesothelioma

Nuclear Medicine Communications 2023 April 28 [Link] Yunus Güzel, Halil Kömek, Canan Can, İhsan Kaplan, Ferat Kepenek, Senar Ebinç, Mehmet Perver Büyükdeniz, Cihan Gündoğan, Zeynep Oruç Abstract Objective: In this study, we aimed to compare the role of 68 Ga-labeled FAP inhibitor ( 68 Ga-FAPI)-04 PET/computed tomography (CT) and 18 F-fluorodeoxyglucose ( 18 F-FDG) PET/CT…

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Epigenetic investigation into circulating microRNA 197-3p in sera from patients affected by malignant pleural mesothelioma and workers ex-exposed to asbestos

Scientific Reports 2023 April 20 [Link] Giulia Di Mauro, Francesca Frontini, Elena Torreggiani, Maria Rosa Iaquinta, Andrea Caselli, Chiara Mazziotta, Valentina Esposito, Elisa Mazzoni, Roberta Libener, Federica Grosso, Antonio Maconi, Fernanda Martini, Ilaria Bononi, Mauro Tognon Abstract The epigenetic role of microRNAs is established at both physiological and pathological levels. Dysregulated miRNAs and their targets…

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One Third of Malignant Pleural Mesothelioma Shows High Immunohistochemical Expression of MSLN or CXCR4 Which Indicates Potent Candidates for Endo-Radiotherapy

International Journal of Molecular Sciences 2023 March 28 [Link] Thomas Hager, Sabrina Borchert, Michael Wessolly, Alexander Mathilakathu, Elena Mairinger, Jens Kollmeier, Thomas Mairinger, Balazs Hegedus, Kristina Greimelmaier, Jeremias Wohlschlaeger, Ken Herrmann, Fabian Dominik Mairinger Abstract Malignant pleural mesothelioma (MPM) is a mainly asbestos-related tumour associated with a very poor prognosis. Therapeutic approaches include multimodal therapy…

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A rare case of primary gastric Burkitt’s lymphoma associated with malignant pleural mesothelioma

Annali Italiani di Chirurgia 2023 March 6 [Link] Erasmo Spaziani, Annalisa Romina Di Filippo, Giampaolo Valle, Martina Spaziani, Piero Francioni, Gianluca Caruso, Giovanni Traumueller Tamagnini, Edoardo Mosciatti, Marcello Picchio, Alessandro De Cesare Abstract Background: Primary gastric Burkitt lymphoma (PG BL) and malignant pleural mesothelioma (MPM) are rare and aggressive tumors with poor prognosis. HIV and…

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Long-Term Survival of More than 5 Years with Maintenance Therapy Using Single-Agent Pemetrexed in a Patient with Diffuse Malignant Peritoneal Mesothelioma

Case Reports in Medicine 2023 February 28 [Link] Yasuo Otsuka, Yoriaki Komeda, Masayuki Takeda, Takayuki Takahama, Masashi Kono, Mamoru Takenaka, Satoru Hagiwara, Naoshi Nishida, Hiroshi Kashida, Masatoshi Kudo Abstract A 76-year-old woman presented with lower abdominal pain and nausea and was referred to the gastroenterology department in our institution. Previous contrast-enhanced computed tomography (CE-CT) for…

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Tumor thickness in mesothelioma predicts differential response to neoadjuvant therapy and survival

The Journal of Thoracic and Cardiovascular Surgery 2022 December 14 [Link] Nicolas Zhou, Cynthia S Bell, Hope A Feldman, Cara L Haymaker, Wayne L Hofstetter, Anne S Tsao, Reza J Mehran, David C Rice, Boris Sepesi; Mesothelioma Immune Genomic Group Abstract Objective: Neoadjuvant systemic therapy in resectable malignant pleural mesothelioma remains controversial and demonstrates variable…

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Coronary Artery Stenosis Caused by Primary Malignant Pericardial Mesothelioma in a 76-Year-Old Man

Texas Heart Institute Journal 2022 November 9 [Link] Yojiro Machii, Akira Sezai, Makoto Taoka, Shunji Osaka, Keito Suzuki, Yoshiki Onuki, Masashi Tanaka Abstract This report describes a 76-year-old man with diabetes mellitus who developed coronary artery stenosis from infiltration of a primary malignant pericardial mesothelioma. Three months before referral to the treating hospital, elevated liver…

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Malignant Peritoneal Mesothelioma Features Shown by FDG-PET/CT

Cancer Diagnosis & Prognosis 2022 November 3 [Link] Kozo Kuribayashi, Kazuhiro Kitajima, Toshiyuki Minami, Masataka Ikeda, Koichiro Yamakado, Takashi Kijima Abstract Background/aim: Malignant peritoneal meso-thelioma (MPeM) has no specific imaging findings that can distinguish it from other peritoneal tumors and the accuracy of peritoneal cytology is low, therefore definitive diagnosis is usually performed by histology.…

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Factors affecting the life expectancy in malignant pleural mesothelioma: Our 10 years of studies and experience

Medicine 2022 September 30 [Link] Filiz Cimen, Yetkin Agackiran, Sevim Düzgün, Melike Aloglu, Aysegül Senturk, Sükran Atikcan Abstract Malignant pleural mesothelioma (MPM) is an aggressive tumor with a poor prognosis. In our study, we aimed to investigate the specific clinical, laboratory, and radiological features of the tumor and the prognostic effect of SUVmax (maximum standardized…

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FDG PET/CT for Staging and Restaging Malignant Mesothelioma

Seminars in Nuclear Medicine 2022 August 11 [Link] Egesta Lopci, Angelo Castello, Luigi Mansi Abstract Malignant mesothelioma is an aggressive tumor originating from the mesothelial cells and presenting in general with a very poor prognosis. The pleural localization represents the prevailing disease site, while peritoneal involvement is commonly rare. The WHO classifies mesotheliomas into epithelioid,…

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