MesotheliomaCenter's

Mesothelioma-Line

Curated Journal Articles on Mesothelioma

Category Archives: CT or CAT scan

Computerized axial tomography (or computed tomography) scan is an x-ray procedure which combines many x-ray images with the aid of a computer to create cross-sectional or three-dimensional images of internal organs and structures within the body.

Air in the Pleural Cavity Enhances Detection of Pleural Abnormalities by CT Scan

Chest 2018 June [Link] Fysh ETH, Thomas R, Tobin C, Kuok YJ, Lee YCG Abstract Detection of pleural abnormalities on CT scan is critical in diagnosis of pleural disease. CT scan detects minute parenchymal lung nodules, but often fails to detect similar-sized pleural nodularity. This is likely because the density of the visceral/parietal pleura and […]

Comments Off on Air in the Pleural Cavity Enhances Detection of Pleural Abnormalities by CT Scan

MR Imaging of Pleural Neoplasms

Topics in Magnetic Resonance Imaging [2018 April] [Link] Carter BW, Betancourt SL, Shroff GS, Lichtenberger JP 3rd Abstract The pleura may be affected by primary tumors or metastatic spread of intrathoracic or extrathoracic neoplasms. Primary pleural neoplasms represent ∼10% of all pleural tumors, and malignant lesions are more common than benign lesions. The most common […]

Comments Off on MR Imaging of Pleural Neoplasms

Randomised controlled trial to compare the diagnostic yield of positron emission tomography CT (PET-CT) TARGETed pleural biopsy versus CT-guided pleural biopsy in suspected pleural malignancy (TARGET trial)

BMJ Open Respiratory Research 2018 February 19 [Link] de Fonseka D, Underwood W, Stadon L, Rahman N, Edey A, Rogers C, Maskell NA Abstract INTRODUCTION: Pleural malignancy, particularly malignant pleural mesothelioma (MPM) is increasing in incidence due to the long latency period from exposure to asbestos to development of the disease. MPM can be challenging […]

Comments Off on Randomised controlled trial to compare the diagnostic yield of positron emission tomography CT (PET-CT) TARGETed pleural biopsy versus CT-guided pleural biopsy in suspected pleural malignancy (TARGET trial)

Malignant Pleural Mesothelioma: Are There Imaging Characteristics Associated With Different Histologic Subtypes on Computed Tomography?

Journal of Computer Assisted Tomography 2018 April 2 [Epub ahead of print] [Link] Escalon JG, Harrington KA, Plodkowski AJ, Zheng J, Capanu M, Zauderer MG, Rusch VW, Ginsberg MS Abstract OBJECTIVES: Determine imaging characteristics specific to epithelioid (eMPM), sarcomatoid (sMPM), and biphasic (bMPM) subtypes of malignant pleural mesothelioma (MPM) on computed tomography. METHODS: Preoperative computed […]

Comments Off on Malignant Pleural Mesothelioma: Are There Imaging Characteristics Associated With Different Histologic Subtypes on Computed Tomography?

Early Contrast Enhancement: A novel magnetic resonance imaging biomarker of pleural malignancy

Lung Cancer 2018 April [Epub 2018 February 3] [Link] Tsim S, Humphreys CA, Cowell GW, Stobo DB, Noble C, Woodward R, Kelly CA, Alexander L, Foster JE, Dick C2, Blyth K Abstract INTRODUCTION: Pleural Malignancy (PM) is often occult on subjective radiological assessment. We sought to define a novel, semi-objective Magnetic Resonance Imaging (MRI) biomarker […]

Comments Off on Early Contrast Enhancement: A novel magnetic resonance imaging biomarker of pleural malignancy

18F-FDG PET/CT in the management of patients with malignant pleural mesothelioma being considered for multimodality therapy: experience of a tertiary referral center

The British Journal of Radiology 2018 March [Epub ahead of print] [Link] H St. AE et.al. Abstract OBJECTIVE: To compare the N and M staging accuracy of positron emission tomography (PET) versus CT, as per the American Joint Committee on Cancer (AJCC) 8th edition in patients with malignant pleural mesothelioma (MPM) being considered for multimodality […]

Comments Off on 18F-FDG PET/CT in the management of patients with malignant pleural mesothelioma being considered for multimodality therapy: experience of a tertiary referral center

A prospective study to investigate the role of serial serum mesothelin in monitoring mesothelioma

BMC Cancer 2018 February 17 [Link] de Fonseka D, Arnold DT, Stadon L, Morley A, Keenan E, Darby M, Armstrong L, Virgo P, Maskell NA Abstract BACKGROUND: Radiological monitoring of malignant pleural mesothelioma (MPM) using modified RECIST criteria is limited by low sensitivity and inter-observer variability. Serial serum mesothelin measurement has shown utility in the […]

Comments Off on A prospective study to investigate the role of serial serum mesothelin in monitoring mesothelioma

Malignant mesothelioma in situ

Histopathology 2018 January [Epub ahead of print] [Link] Churg A, Hwang H, Tan L, Qing G, Taher A, Tong A, Bilawich A, Dacic S Abstract The existence of malignant mesothelioma in situ (MIS) is often postulated, but there are no accepted morphologic criteria for making such a diagnosis. Here we report two cases that appear […]

Comments Off on Malignant mesothelioma in situ

Endoscopic ultrasound-guided fine-needle aspiration from ascites and peritoneal nodules: A scoping review

Endoscopic Ultrasound 2017 November-December [Link] Sharma V, Rana SS, Ahmed SU, Guleria S, Sharma R, Gupta R Abstract The peritoneum is involved in many diseases such as primary malignancy (mesothelioma), infectious disease (tuberculosis), and disseminated malignancy (peritoneal carcinomatosis). The peritoneal disease may manifest as ascites and/or peritoneal masses or nodules. Endoscopic ultrasound (EUS), due to […]

Comments Off on Endoscopic ultrasound-guided fine-needle aspiration from ascites and peritoneal nodules: A scoping review

Targeting CXCR4 with [68Ga]Pentixafor: a suitable theranostic approach in pleural mesothelioma?

Oncotarget 2017 November 14 [Link] Lapa C et. al. Abstract C-X-C motif chemokine receptor 4 (CXCR4) is a key factor for tumor growth and metastasis in several types of human cancer. This study investigated the feasibility of CXCR4-directed imaging with positron emission tomography/computed tomography (PET/CT) using [68Ga]Pentixafor in malignant pleural mesothelioma. Six patients with pleural […]

Comments Off on Targeting CXCR4 with [68Ga]Pentixafor: a suitable theranostic approach in pleural mesothelioma?