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Curated Journal Articles on Mesothelioma

Category Archives: Diagnosis & Differentiation

Air in the Pleural Cavity Enhances Detection of Pleural Abnormalities by CT Scan

Chest 2018 June [Link] Fysh ETH, Thomas R, Tobin C, Kuok YJ, Lee YCG Abstract Detection of pleural abnormalities on CT scan is critical in diagnosis of pleural disease. CT scan detects minute parenchymal lung nodules, but often fails to detect similar-sized pleural nodularity. This is likely because the density of the visceral/parietal pleura and […]

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Soluble CD157 in pleural effusions: a complementary tool for the diagnosis of malignant mesothelioma.

Oncotarget 2018 April 27 [Link] Augeri S, Capano S, Morone S, Fissolo G, Giacomino A, Peola S, Drace Z, Rapa I, Novello S, Volante M, Righi L, Ferrero E, Ortolan E, Funaro A Abstract BACKGROUND: CD157/Bst1 glycoprotein is expressed in >85% of malignant pleural mesotheliomas and is a marker of enhanced tumor aggressiveness. RESULTS: In […]

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Antitumor efficacy of Kisspeptin in human malignant mesothelioma cells

Oncotarget 2018 April [Link] Ciaramella V, Della Corte CM, Di Mauro C, Tomassi S, Di Maro S, Troiani T, Martinelli E, Bianco R, Cosconati S, Pierantoni R, Meccariello R, Chianese R, Ciardiello F, Morgillo F Abstract PURPOSE: Kisspeptin signaling, via its receptors GPR54, could be an essential players in the inhibition of mesothelioma progression, invasion […]

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Video-assisted thoracoscopic PlasmaJet ablation for malignant pleural mesothelioma.

Journal of visualized surgery 2018 March [Link] Perikleous P, Asadi N, Anikin V Abstract The role of surgery in malignant pleural mesothelioma (MPM) remains debatable; nonetheless the relative advantages of different surgical approaches are frequently reassessed and reconsidered. While extensive operations and longer recovery periods can be justified for a group of carefully selected patients, […]

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New Perspectives on Diagnosis and Therapy of Malignant Pleural Mesothelioma

Frontiers in Oncology 2018 April [Link] Rossini M, Rizzo P, Bononi I, Clementz A, Ferrari R, Martini F, Tognon MG Abstract Malignant pleural mesothelioma (MPM) is a rare, but severe form of cancer, with an incidence that varies significantly within and among different countries around the world. It develops in about one to two persons […]

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MR Imaging of Pleural Neoplasms

Topics in Magnetic Resonance Imaging [2018 April] [Link] Carter BW, Betancourt SL, Shroff GS, Lichtenberger JP 3rd Abstract The pleura may be affected by primary tumors or metastatic spread of intrathoracic or extrathoracic neoplasms. Primary pleural neoplasms represent ∼10% of all pleural tumors, and malignant lesions are more common than benign lesions. The most common […]

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Malignant pleural mesothelioma: diagnostic value of medical thoracoscopy and long-term prognostic analysis

Pulmonary Medicine 2018 April 3 [Link] Xu LL, Yang Y, Wang Z, Wang XJ, Tong ZH, Shi HZ Abstract BACKGROUND: Malignant pleural mesothelioma (MPM) is marked by its difficult diagnosis and poor prognosis. Medical thoracoscopy (MT) is an effective and safe procedure for the diagnosis of exudative pleural effusions and many factors associated with poor […]

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Randomised controlled trial to compare the diagnostic yield of positron emission tomography CT (PET-CT) TARGETed pleural biopsy versus CT-guided pleural biopsy in suspected pleural malignancy (TARGET trial)

BMJ Open Respiratory Research 2018 February 19 [Link] de Fonseka D, Underwood W, Stadon L, Rahman N, Edey A, Rogers C, Maskell NA Abstract INTRODUCTION: Pleural malignancy, particularly malignant pleural mesothelioma (MPM) is increasing in incidence due to the long latency period from exposure to asbestos to development of the disease. MPM can be challenging […]

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Malignant Pleural Mesothelioma: Are There Imaging Characteristics Associated With Different Histologic Subtypes on Computed Tomography?

Journal of Computer Assisted Tomography 2018 April 2 [Epub ahead of print] [Link] Escalon JG, Harrington KA, Plodkowski AJ, Zheng J, Capanu M, Zauderer MG, Rusch VW, Ginsberg MS Abstract OBJECTIVES: Determine imaging characteristics specific to epithelioid (eMPM), sarcomatoid (sMPM), and biphasic (bMPM) subtypes of malignant pleural mesothelioma (MPM) on computed tomography. METHODS: Preoperative computed […]

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Early Contrast Enhancement: A novel magnetic resonance imaging biomarker of pleural malignancy

Lung Cancer 2018 April [Epub 2018 February 3] [Link] Tsim S, Humphreys CA, Cowell GW, Stobo DB, Noble C, Woodward R, Kelly CA, Alexander L, Foster JE, Dick C2, Blyth K Abstract INTRODUCTION: Pleural Malignancy (PM) is often occult on subjective radiological assessment. We sought to define a novel, semi-objective Magnetic Resonance Imaging (MRI) biomarker […]

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