Does Simian Virus 40 (SV40) Have a Role in UK Malignant Pleural Mesothelioma? No Role is Identified in a Sensitive RNA In Situ Hybridization Study on Potentially Affected Birth Cohorts.

Applied Immunohistochemistry & Molecular Morphology 2019 June 12 [Link] Alchami FS, Attanoos RL, Gibbs A, Morgan F, Jasani B Abstract BACKGROUND: Simian virus 40 (SV40)-contaminated polio vaccine was accidentally administered to about one-third of the UK population receiving polio vaccines between 1956 and 1962. SV40 was subsequently demonstrated to be a carcinogenic virus in experimental…

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Simian virus 40 sequences in blood specimens from healthy individuals of Casale Monferrato, an industrial town with a history of asbestos pollution

Journal of Infection. 2009 Jan;58(1):53-60. Epub 2008 Dec 13. [Link] Pancaldi C, Balatti V, Guaschino R, Vaniglia F, Corallini A, Martini F, Mutti L, Tognon M. Department of Morphology and Embryology, Section of Cell Biology and Molecular Genetics, University of Ferrara, Ferrara, Italy. Abstract Objective: Asbestos is considered the main agent in causing the onset…

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Pathogenesis of malignant pleural mesothelioma and the role of environmental and genetic factors

Journal of Cancer Research and Clinical Oncology. 2009 Jan;135(1):15-27. Epub 2008 Sep 12. [Link] Weiner SJ, Neragi-Miandoab S. Cleveland Clinic Lerner College of Medicine, 9500 Euclid Avenue, Cleveland, OH, USA. Abstract Background: Malignant pleural mesothelioma (MPM) is a rare and aggressive tumor for which no effective therapy exists despite the discovery of many possible molecular…

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The role of polio-vaccine in pleural mesothelioma–an epidemiological observation

Collegium Antropologicum. 2008 Jun;32(2):479-83. [Link] Sarić M, Curin K, Varnai VM. Institute for Medical Research and Occupational Health, Zagreb, Croatia. marko@imi.hr Abstract From the Croatian Cancer Registry (period 1991-1997) 194 malignant pleural mesothelioma patients were collected. According to participation in polio vaccination mass campaign in 1961 that covered the entire Croatian population aged 3 months…

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Mesothelioma Epidemiology, Carcinogenesis, and Pathogenesis

Current Treatment Options in Oncology. 2008 Aug 15. [Epub ahead of print] [Link] Yang H, Testa JR, Carbone M. Cancer Research Center of Hawaii, University of Hawaii, Honolulu, HI, 96813, USA. Abstract Opinion Statement: The incidence of mesothelioma has gone from almost none to the current 2500-3000 cases per year in the USA. This estimate…

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SV40 large T antigen-specific human T cell memory responses

Journal of Medical Virology. 2008 Jun 12;80(8):1497-1504. [Epub ahead of print] [Link] Coleman S, Gibbs A, Butchart E, Mason MD, Jasani B, Tabi Z. Velindre Hospital, Velindre NHS Trust, Cardiff, United Kingdom. Abstract The continued presence of simian virus 40 (SV40), a monkey polyomavirus, in man is confirmed by the regular detection of SV40-specific antibodies…

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Malignant mesothelioma 2008

Current Opinion in Pulmonary Medicine. 14(4):303-309, July 2008. [Link] Zervos MD, Bizekis C, Pass HI. Department of Cardiothoracic Surgery, Division of Thoracic Surgery, New York University School of Medicine, New York, USA. zervom01@med.nyu.edu Abstract Purpose of review: Mesothelioma is an aggressive malignancy of the pleura with poor survival. There will be approximately 3000 cases of…

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The relationship between simian virus 40 and mesothelioma

Current Opinion in Pulmonary Medicine. 14(4):316-321, July 2008. [Link] Rivera Z, Strianese O, Bertino P, Yang H, Pass H, Carbone M. Cancer Research Center of Hawaii and Department of Pathology, University of Hawaii, Honolulu, Hawaii, USA . Abstract Purpose of review: Simian virus 40 is present in some human malignant mesotheliomas. The evidence in favor…

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Mesothelioma due to environmental exposure to erionite in Turkey

Current Opinion in Pulmonary Medicine. 14(4):322-325, July 2008. [Link] Dikensoy O. Department of Pulmonary Diseases, Gaziantep University, Gaziantep, Turkey. dikensoy@yahoo.com Abstract Purpose of review: The prevalence of malignant mesothelioma due to erionite exposure in Central Anatolia is very high. In this report, we review the recent developments on this epidemic on the basis of previous…

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Establishment of three novel human malignant pleural mesothelioma cell lines: morphological and cytogenetical studies and EGFR mutation status

Anticancer Research. 2008 Jan-Feb;28(1A):197-208. [Link] Kobayashi M, Takeuchi T, Ohtsuki Y. Department of Respiratory Medicine, Hosogi Hospital, 37 Daizen-cho, Kochi, Kochi 780-8535, Japan. kmakoto@jinseikai-group.or.jp Abstract Introduction: The incidence of mesothelioma is estimated to rise sharply worldwide, including Japan, in the next two decades. Molecular and proteomic studies are urgently required to elucidate the pathobiology of…

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