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Curated Journal Articles on Mesothelioma

Category Archives: Occupational Asbestos Exposure

A wide variety of companies and industries used, and even continue to use, asbestos. While asbestos has never respected job titles, working in certain occupations and industries may increase your likelihood (and that of your family via contaminated clothing) of having been exposed to asbestos.

New Perspectives on Diagnosis and Therapy of Malignant Pleural Mesothelioma

Frontiers in Oncology 2018 April [Link] Rossini M, Rizzo P, Bononi I, Clementz A, Ferrari R, Martini F, Tognon MG Abstract Malignant pleural mesothelioma (MPM) is a rare, but severe form of cancer, with an incidence that varies significantly within and among different countries around the world. It develops in about one to two persons […]

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Asbestos Fiber Concentrations in the Lungs of Brake Repair Workers: An Updated Analysis Using Several Regression Methods to Handle Non-Detectable Measurements

Journal of Occupational and Environmental Medicine 2018 March [Epub ahead of print] [Link] Liu Y1, Marsh GM, Roggli VL Abstract OBJECTIVES: To reanalyze an updated database of lung asbestos fiber levels for 21 brake repair workers who died of mesothelioma using robust maximum likelihood-based regression methods to address non-detectable measurements. METHODS: We applied bivariate normal […]

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DNA methylation profiling of asbestos-treated MeT5A cell line reveals novel pathways implicated in asbestos response

Archives of Toxicology 2018 March [Epub ahead of print] [Link] Casalone E et. al. Abstract Occupational and environmental asbestos exposure is the main determinant of malignant pleural mesothelioma (MPM), however, the mechanisms by which its fibres contribute to cell toxicity and transformation are not completely clear. Aberrant DNA methylation is a common event in cancer […]

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Heterogeneous Contributing Factors in MPM Disease Development and Progression: Biological Advances and Clinical Implications

International Journal of Molecular Science 2018 January 13 [Link] Tolani B, Acevedo LA, Hoang NT, He B Abstract Malignant pleural mesothelioma (MPM) tumors are remarkably aggressive and most patients only survive for 5-12 months; irrespective of stage; after primary symptoms appear. Compounding matters is that MPM remains unresponsive to conventional standards of care; including radiation […]

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Chest physician-reported, work-related, long-latency respiratory disease in Great Britain

The European Respiratory Journal 2017 December [Link] Carder M, Darnton A, Gittins M, Stocks SJ, Ross D, Barber CM, Agius RM Abstract Much of the current burden of long-latency respiratory disease (LLRD) in Great Britain is attributed to historical asbestos exposure. However, continuing exposure to other agents, notably silica, also contributes to disease burden. The […]

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Biological responses to asbestos inhalation and pathogenesis of asbestos-related benign and malignant disease

Journal of Investigative Medicine 2018 January 6 [Epub ahead of print] [Link] Solbes E, Harper RW Abstract Asbestos comprises a group of fibrous minerals that are naturally occurring in the environment. Because of its natural properties, asbestos gained popularity for commercial applications in the late 19th century and was used throughout the majority of the […]

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The epidemiology of malignant mesothelioma in women: gender differences and modalities of asbestos exposure

Occupational and Environmental Medicine 2017 December 21 [Epub ahead of print] [Link] Marinaccio A, et. al. Abstract INTRODUCTION: The epidemiology of gender differences for mesothelioma incidence has been rarely discussed in national case lists. In Italy an epidemiological surveillance system (ReNaM) is working by the means of a national register. METHODS: Incident malignant mesothelioma (MM) […]

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Breath analysis by gas chromatography-mass spectrometry and electronic nose to screen for pleural mesothelioma: a cross-sectional case-control study

Oncotarget 2017 September [Link] Lamote K, et. al Abstract RATIONALE: Malignant pleural mesothelioma (MPM) is mainly caused by previous exposure to asbestos fibers and has a poor prognosis. Due to a long latency period between exposure and diagnosis, MPM incidence is expected to peak between 2020-2025. Screening of asbestos-exposed individuals is believed to improve early […]

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Plasma Fibulin-3 as a Potential Biomarker for Patients with Asbestos-Related Diseases in the Han Population

Disease Markers 2017 [Epub 2017 October 22] [Link] Jiang Z et. al. Abstract Fibulin-3 has been reported as a potential biomarker for mesothelioma. However, little is known about the diagnostic efficacies of fibulin-3 for asbestos-related diseases (ARDs) in China. This study was to investigate the utility of fibulin-3 for asbestos exposure and ARDs. A total […]

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Mesothelioma in Australia: a review

The Medical Journal of Australia 2017 November 20 [Link] Musk ABW, de Klerk N, Brims FJ Abstract The incidence of malignant mesothelioma in Australia is among the highest in the world as a result of widespread use of asbestos by industry and in construction throughout the 20th century. The risk of developing malignant mesothelioma after […]

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